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2000 articles
October 202624
Renoprotective effects and safety of sodium-glucose cotransporter 2 inhibitors in diabetic chronic kidney disease: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors on patients with diabetic chronic kidney disease (CKD).
Angioimmunoblastic T-cell lymphoma with secondary hemophagocytic lymphohistiocytosis initially misdiagnosed as classical Hodgkin lymphoma: A case report.
A 72-year-old man presented with fatigue, recurrent fever, severe pancytopenia, and splenomegaly, initially diagnosed with Hodgkin lymphoma.
Hereditary Neuropathies.
This article describes the clinical features, genetic causes, and diagnostic strategies of inherited peripheral neuropathies, and highlights how recent developments are reshaping the management of these disorders.
Recurrent giant retroperitoneal liposarcoma: A case report.
A 48-year-old male with a 13-year history of recurrent myxoid liposarcoma presented with significant abdominal distension due to a massive abdominopelvic mass measuring 352 mm.
Cerebrospinal fluid shunting for idiopathic normal pressure hydrocephalus: a comprehensive meta‑analysis with trial sequential analysis of randomized controlled trials.
This meta-analysis evaluated the efficacy of cerebrospinal fluid (CSF) shunting in adults aged 60 and older with idiopathic normal pressure hydrocephalus (iNPH).
Primary pulmonary mucosa-associated lymphoid tissue lymphoma presenting as a right hilar mass: A case report.
A 44-year-old male presented with an incidental right hilar mass discovered during routine screening. He was asymptomatic, and imaging revealed a 3.9 × 3.5 cm mass causing bronchial compression and post-obstructive…
Safety profile of elafibranor versus placebo in primary biliary cholangitis: A systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the safety profile of elafibranor compared to placebo in patients with primary biliary cholangitis (PBC) who did not adequately respond to first-line therapy.
Excellent response to high-dose Riboflavin in Brown-Vialetto-Van Laere syndrome: A case report.
A young Asian man presented with progressive bilateral hearing loss, dysphagia, limb weakness, and respiratory issues. Neurological examination revealed significant deficits, and genetic testing confirmed pathogenic…
Serum 25-hydroxyvitamin D levels are associated with thyroid diseases: A systematic review and meta-analysis.
This systematic review and meta-analysis examined the relationship between serum 25-hydroxyvitamin D levels and thyroid diseases, including autoimmune thyroid diseases (AITDs).
Endoscopic double-layer nylon rope ligation for rescue of gastric ulcer bleeding after failed OTSC treatment: A case report (with video).
A 61-year-old man presented with hematemesis and melena due to a bleeding gastric ulcer classified as Forrest IIa. After initial treatment with an over-the-scope clip (OTSC) failed, he underwent endoscopic double-layer…
Narrative nursing for prolonged myelosuppression after autologous stem cell transplantation in multiple myeloma: A case report.
A 46-year-old man with multiple myeloma was admitted 7 months post-autologous stem cell transplantation due to febrile neutropenia and erosive oral mucosal lesions.
Perioperative adrenal insufficiency presenting as refractory hypotension: A CARE-compliant article.
A 77-year-old woman undergoing lumbar fusion surgery experienced severe hypotension that did not respond to fluid resuscitation or vasopressors.
Androgen insensitivity syndrome: A case report.
A 29-year-old phenotypic female presented with primary amenorrhea and intermittent abdominal pain. Examination revealed normal breast development, sparse pubic hair, and female external genitalia.
Antibiotic Stewardship in Nonoperative Facial Trauma: Necessary or Not?
This systematic review evaluated the effectiveness of prophylactic antibiotics in preventing infections in adults with closed, nonoperative facial fractures.
Genetic evidence for associations between gastroesophageal reflux disease and site-specific extraesophageal cancers: A Mendelian randomization study.
This Mendelian randomization study investigated the relationship between genetically predicted gastroesophageal reflux disease (GERD) and 22 extraesophageal cancers using data from over 600,000 individuals.
Cholecystogastric fistula masquerading as gastrointestinal stromal tumour: Unusual presentation of gallbladder adenomyomatosis - a case report.
A 71-year-old woman presented with acute abdominal pain and signs of mechanical small-bowel obstruction. Imaging revealed a 6-cm mass near the gastric antrum, initially suspected to be an invasive gastrointestinal…
Participant experiences of stopping ART as part of a clinical trial; findings from a qualitative study within the RIO trial in the United Kingdom.
This qualitative study explored the experiences of 20 cisgender men living with HIV who participated in the phase 2 RIO trial, which involved analytical treatment interruptions (ATIs).
Rapid manufactured CAR-T cells enriched for CD45RA-negative T cells exhibit superior persistence compared to conventional CAR-T therapy.
This comparative study evaluated InstanCAR-T, a rapid CD19 CAR-T manufacturing protocol enriched for CD45RA-negative T cells, against conventional CAR-T in laboratory assays, murine B-ALL models, and a Phase I clinical…
40 Hz transcutaneous auricular vagus nerve stimulation enhances verbal free recall in healthy adults by modulating frontal theta oscillations.
This randomized, single-blind, sham-controlled, three-arm trial examined whether 20 Hz or 40 Hz transcutaneous auricular vagus nerve stimulation (taVNS) affected verbal free recall and resting-state EEG theta activity…
Pulmonary cryptococcosis mimicking metastatic progression despite systemic disease stability in advanced colon cancer: A case report and literature review.
A patient with advanced colon cancer undergoing chemotherapy presented with new pulmonary nodules on imaging, despite stable systemic disease and declining tumor markers.
Paraproteinemic Neuropathies.
Paraproteinemic neuropathies present with a myriad of phenotypes and associated underlying plasma cell dyscrasias. This article provides a phenotype-driven approach to the evaluation of paraproteinemic neuropathies…
Regional practice differences significantly affect the benefit of post-HCT gilteritinib in FLT3-ITD AML.
The phase 3 MORPHO trial evaluated the efficacy of gilteritinib versus placebo in post-hematopoietic cell transplantation (HCT) for FLT3-ITD AML patients.
Outcome assessment in frozen shoulder trials: A systematic review and COSMIN-informed recommendations.
This systematic review mapped outcome measures in 927 randomized controlled trials (RCTs) of frozen shoulder and conducted a COSMIN-informed appraisal of measurement-property evidence for commonly used instruments.
MRD negativity by PBMCs and ctDNA confirms deep and durable responses after epcoritamab monotherapy in R/R FL.
The EPCORE NHL-1 trial evaluated the efficacy of epcoritamab, a CD3 × CD20 bispecific antibody, in patients with relapsed/refractory follicular lymphoma (FL) after at least two prior therapies.
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