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1999 articles

October 202624

Clinical ResearchNephrology

Crescents in native kidney biopsies from patients with IgA nephropathy and the risk of recurrence after kidney transplantation: a retrospective cohort study, systematic literature review and meta-analysis of observational studies.

This retrospective cohort study, systematic review and meta-analysis examined whether glomerular crescents in native kidney biopsies predict IgA nephropathy (IgAN) recurrence after kidney transplantation.

J NephrolOct 22, 2026Read summary
Clinical ResearchPediatrics

Clinical performance of resin infiltration and different sealant modalities in noncavitated pits and fissures: a split-mouth randomized controlled trial.

This split-mouth randomized controlled trial compared resin infiltration, two sealant approaches, and their combination for noncavitated occlusal lesions in 128 permanent molars from 32 children aged 7–14 years.

Quintessence IntOct 22, 2026Read summary
Clinical ResearchHematology

Concurrent administration of BCMA and GPRC5D CAR T cells for advanced multiple myeloma.

This phase 1 dose-escalation trial evaluated BCMA-directed CAR T-cell therapy MCARH125 alone or infused concurrently with GPRC5D-directed MCARH109 in patients with relapsed or refractory multiple myeloma.

BloodOct 22, 2026Read summary
Clinical ResearchCardiologyOpen access

Wireless Home Blood Pressure Monitoring With Health Coaching for Hypertension Management at a Federally Qualified Health Center: Pilot Randomized Controlled Feasibility and Acceptability Study.

This 6-month, two-arm randomized pilot trial assessed feasibility and acceptability of wireless home blood pressure monitoring (HBPM) with health coaching among adults with uncontrolled or newly diagnosed hypertension…

JMIR Form ResOct 22, 2026Read summary
Case ReportNephrology

From inference to proof: nanopore sequencing confirms zoonotic Neisseria Zoodegmatis peritonitis after cat bite-related contamination in a patient on automated peritoneal dialysis.

A 90-year-old patient receiving automated peritoneal dialysis developed peritonitis after a cat bite damaged the transfer set. Empirical therapy produced only a partial response, followed by relapse.

J NephrolOct 22, 2026Read case
Clinical ResearchNeurologyOpen access

Locus coeruleus abnormalities on neuromelanin-sensitive MRI in Parkinson's disease: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed locus coeruleus (LC) integrity on neuromelanin-sensitive MRI in Parkinson’s disease (PD), pooling independent comparisons with healthy controls using random-effects…

J NeurolOct 22, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Patients with MASH experience worse health-related quality of life: a multinational real-world study using LiverMultiScan.

This multinational real-world randomised controlled trial examined health-related quality of life (HRQoL) and liver MRI markers in 802 people with suspected MASLD/MASH across four European countries.

Qual Life ResOct 22, 2026Read summary
Clinical ResearchUrologyOpen access

Novel Imaging Techniques Prior to Surgical Management of Invasive Bladder Cancer: A Systematic Review.

This PRISMA-guided systematic review assessed novel imaging for detecting muscle invasion and nodal disease before surgical management of invasive bladder cancer. It included 33 studies encompassing 4,689 patients.

Curr Urol RepOct 22, 2026Read summary
Clinical ResearchDermatologyOpen access

Thulium laser-assisted delivery of growth factors for treating androgenetic alopecia - a randomized, controlled, clinical study.

This pilot randomized controlled study evaluated non-ablative fractional laser (NAFL)-assisted delivery of a biomimetic growth factor serum, with or without red light therapy, in patients with androgenetic alopecia.

Lasers Med SciOct 22, 2026Read summary
Case ReportRheumatologyOpen access

Avoiding Diagnostic Overshadowing: A Case Series on Cervical Myelopathy in Patients with Fibromyalgia.

Three patients referred to a multidisciplinary chronic pain clinic for fibromyalgia evaluation had substantial physical and neurological impairment.

Int Med Case Rep JOct 22, 2026Read case
Clinical ResearchInfectious Diseases

Safety and immunogenicity of the 24-valent pneumococcal conjugate vaccine in healthy Chinese adults: two single-center, randomized, double-blind Phase 1 and Phase 2 trials.

Two single-center, randomized, double-blind Phase 1 and Phase 2 trials assessed the safety and immunogenicity of a 24-valent pneumococcal conjugate vaccine (PCV24) in healthy Chinese adults aged 18 years or older.

Expert Rev VaccinesOct 22, 2026Read summary
Case ReportAnesthesiology

Anaesthetic Management of a Child with Chromosome 7q32.1 Microdeletion Undergoing Ligation of Patent Processus Vaginalis.

A six-year-old boy with chromosome 7q32.1 microdeletion, autism spectrum disorder, attention deficit hyperactivity disorder, hypotonia and asthma underwent elective ligation of a patent processus vaginalis under general…

Ir Med JOct 22, 2026Read case
Clinical ResearchOrthopedic SurgeryOpen access

Mid-term clinical outcomes and isokinetic performance after primary total knee arthroplasty within a modified ERAS protocol: a single-blinded randomized controlled trial.

This prospective, single-blinded randomized controlled trial compared a modified Enhanced Recovery After Surgery (ERAS) protocol with conventional perioperative care in 58 patients undergoing primary total knee…

BMC Musculoskelet DisordOct 22, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Avatar-led digital health intervention for sexual and gender minority young adult smoking cessation: randomized controlled pilot trial.

This randomized controlled pilot trial compared EQQUAL, an Acceptance and Commitment Therapy-based digital smoking cessation program tailored for sexual and gender minority (SGM) young adults, with Smokefree.gov.

Nicotine Tob ResOct 22, 2026Read summary
Clinical ResearchNeurologyOpen access

Efficacy and Safety of Argatroban as an Adjunct to Antiplatelet Therapy in Ischemic Stroke: An Updated Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed argatroban added to antiplatelet therapy versus control in acute ischemic stroke.

Eur J Clin PharmacolOct 22, 2026Read summary
Case ReportOncology (Medical)

From metastatic disease to no evidence of disease after conversion liver surgery in advanced gastric cancer with liver metastases: A case report.

A 54-year-old woman with initially unresectable, HER2-negative, pMMR-by-IHC, EBER-positive gastric cancer and synchronous liver metastases received tislelizumab-based chemotherapy, with regimen changes after suspected…

Hum Vaccin ImmunotherOct 22, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Clinical safety, tolerability, and efficacy of fospropofol disodium for sedation: a systematic review.

This systematic review and meta-analysis assessed randomized trials of fospropofol for procedural and ICU sedation. It included 10 studies: six procedural-sedation trials and four ICU-sedation trials.

Eur J Clin PharmacolOct 22, 2026Read summary
Clinical ResearchNeurosurgery

Patterns and predictive factors of hearing loss following microvascular decompression for hemifacial spasm: a systematic review.

This systematic review and meta-analysis assessed the prevalence, patterns, and potential risk factors for hearing loss after microvascular decompression for hemifacial spasm.

Neurosurg RevOct 22, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Effects of exposure to negative and positive social media content about vaping and nicotine addiction on beliefs and intentions to use e-cigarettes among young adults in the United States: results from a randomized controlled experiment.

This randomized controlled experiment assigned 1,816 young adults in the United States to view real, publicly accessible social media videos presenting nicotine addiction positively, negatively, or in unrelated control…

Nicotine Tob ResOct 22, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Disentangling direct and weight-mediated effects of physical activity on health-related quality of life in a 12-month real-world digital lifestyle intervention.

This longitudinal study examined physical activity and health-related quality of life (HRQoL) among 1,732 people participating in a 12-month digital lifestyle program; the abstract identifies it as a clinical trial but…

Qual Life ResOct 22, 2026Read summary
Clinical ResearchNeurologyOpen access

Determining the minimal important difference of EQ-5D-5 L utility values in CIDP patients using data from a large clinical trial.

This analysis of data from the ADHERE randomized controlled trial estimated the minimal important difference (MID) in EQ-5D-5 L utility values for patients with chronic inflammatory demyelinating polyradiculoneuropathy…

Qual Life ResOct 22, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

The effect of telephone-based education and counselling on stoma adjustment and complication severity in individuals with a colostomy: a randomised controlled trial.

This randomised controlled trial evaluated telephone-based education and counselling for people with a colostomy, compared with routine stoma care.

Support Care CancerOct 22, 2026Read summary
Clinical ResearchGeriatrics

Agreement Between In-Person and Telephone Application of the Informant Questionnaire on Cognitive Decline in the Elderly.

This methodological study assessed agreement between in-person and telephone administration of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), completed by caregivers or family members of older…

PsychogeriatricsOct 22, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Administration-order effects in head-to-head comparisons of the EQ-5D-3L and EQ-5D-5L descriptive systems: evidence from a randomised general-population panel in Great Britain.

This randomised study in a general-population panel in Great Britain examined whether administration order affects comparisons of the EQ-5D-3L and EQ-5D-5L.

Qual Life ResOct 22, 2026Read summary

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