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1999 articles
October 202624
Efficacy and safety of tolebrutinib in multiple sclerosis: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed tolebrutinib’s efficacy and safety in multiple sclerosis, drawing on four publications covering four randomised controlled trials and one long-term extension study.
Association of dietary choline intake with cognitive decline and related outcomes: a systematic review and dose-response meta-analysis of observational studies.
This systematic review and dose-response meta-analysis examined observational evidence on dietary choline intake and cognitive decline or related outcomes.
Walnut consumption improves mood and is associated with increased urinary excretion of 5-hydroxyindoleacetic acid and urolithins in a randomized crossover trial.
This 18-week open-label randomized crossover trial assessed whether daily walnut consumption affected mood and urinary metabolites in 31 healthy young adults.
Delayed diagnosis of cerebrotendinous xanthomatosis with progressive neurological involvement: a case report.
A 34-year-old man with genetically confirmed cerebrotendinous xanthomatosis presented with progressive gait instability, dysarthria, dysphagia, and cognitive impairment.
Comparative efficacy of interventions for preventing chemotherapy-induced alopecia: a systematic review and network meta-analysis.
This systematic review and network meta-analysis compared preventive interventions for chemotherapy-induced alopecia in cancer patients, including 12 randomized trials with 736 participants and nine intervention groups.
Psychological Factors Associated with Function and Health-Related Quality of Life Outcomes following Total Hip or Knee Arthroplasty: An Umbrella Review of Systematic Reviews.
This umbrella review synthesised high-quality evidence from systematic reviews on psychological factors associated with function and health-related quality of life after total hip or knee arthroplasty.
Evaluating the impact of conditional micro-incentives on linkage to HIV care in rural South Africa: results from the Home-Based Intervention to Test and Start (HITS) trial.
The HITS real-world randomized trial assessed whether conditional food vouchers improved linkage to HIV care after home-based testing in rural KwaZulu-Natal, South Africa.
Cost-effectiveness of monotherapy and combination therapy for myopia control in Chinese children.
This network meta-analysis and decision-analytic Markov model assessed the cost-effectiveness of 16 myopia-control strategies for Chinese children and adolescents, modelling eight-year-old children over eight years.
The effectiveness of meaning-based interventions in reducing suicide-related vulnerability: A systematic review.
This systematic review examined whether meaning-based interventions affect suicide-related outcomes and how their effects may operate.
POCUS Image Archiving in Emergency Medicine: A Systematic Review of Clinical and Financial Impacts.
This systematic review assessed clinical, operational, and financial outcomes of archiving point-of-care ultrasound (POCUS) images in electronic health records in emergency departments.
High-Resolution Ultrasound in the Evaluation of Median and Superficial Radial Nerve Involvement in Neurofibromatosis Type 1.
A 16-year-old girl with neurofibromatosis type 1 presented with hand pain and paresthesia. High-resolution ultrasound showed a hypervascular superficial neurofibroma, marked epineural thickening of the median nerve…
Efficacy and safety of ifupinostat in relapsed or refractory diffuse large B-cell lymphoma: a multicenter, single-arm phase 2 study.
This multicenter, single-arm phase 2 study evaluated intravenous ifupinostat monotherapy in patients with relapsed or refractory diffuse large B-cell lymphoma after at least two prior systemic therapy lines.
Metal Hypersensitivity Reactions Following Spinal Implants: A Systematic Review.
This systematic review examined clinical presentation, diagnostic approaches, and outcomes of metal hypersensitivity after spinal implant surgery in adults.
Characterizing Behavioral Engagement in Smartphone Cognitive Behavioral Therapy for Obsessive Compulsive Disorder: Secondary Analysis of a Randomized Controlled Trial.
This exploratory secondary analysis of a 12-week randomized controlled trial examined behavioral engagement with smartphone cognitive behavioral therapy for obsessive compulsive disorder (OCD) in 60 participants.
Isolated Bilateral Periocular Lupus Miliaris Disseminatus Faciei: A Clinicopathological Mimicker of Granulomatosis With Polyangiitis.
A healthy young adult man presented with symmetrical papules confined to both periocular regions. Eyelid biopsy showed suppurative necrotizing granulomatous inflammation, prompting concern for granulomatosis with…
Clinical and functional outcomes of aquatic plyometrics in adolescent patellofemoral pain syndrome: a dual-arm randomized controlled trial.
This dual-arm randomized controlled trial compared aquatic plyometric exercises with conventional exercises in 56 adolescents aged 10–18 years with patellofemoral pain syndrome.
Robotic resection of cardiac papillary fibroelastoma guided by three-dimensional transesophageal echocardiography: a case report.
A patient was diagnosed with a papillary fibroelastoma involving the mitral valve. Three-dimensional transesophageal echocardiography (3D TEE) was used to characterize the suspected lesion and assess its anatomy…
Safety and effectiveness of the Vertex Pulmonary Embolectomy System in acute intermediate-risk pulmonary embolism: the SPIRARE II pivotal trial.
SPIRARE II was a prospective, single-arm, multicentre pivotal trial evaluating the Vertex Pulmonary Embolectomy System for aspiration thrombectomy in patients with acute intermediate-risk pulmonary embolism.
Descemet stripping only combined with cataract surgery and extended-depth-of-focus intraocular lens implantation: a surgical strategy and exploratory clinical evidence.
Three patients with Fuchs endothelial dystrophy, preserved peripheral endothelium, and visually significant cataract underwent combined Descemet stripping only, phacoemulsification, and implantation of a Vivity…
Effects of the GnRH agonist leuprorelin on liver volume in premenopausal women with severe polycystic liver disease.
This prospective, open-label randomized trial evaluated leuprorelin in premenopausal women aged 18–45 years with severe polycystic liver disease (PLD).
Loop Taping for Heel Fat Pad Syndrome: A Crossover Pilot Randomized Controlled Trial.
This two-period crossover pilot randomized controlled trial assessed loop taping in adults with heel fat pad syndrome, comparing it with control taping in randomized order.
Coronary artery disease management in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis of randomised trials compared coronary revascularisation strategies in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI).
Daily consumption of unsalted, skin-roasted peanuts beneficially affects regional brain insulin responsiveness in older adults: results of a longer-term randomized controlled trial.
This randomized, single-blind, controlled crossover trial examined whether peanut intake altered brain insulin responsiveness in 31 older adults (67 ± 4 years).
Cerebrospinal fluid positive for SARS-CoV-2 associated with neurological manifestations and proteome alterations in a multiple myeloma patient.
A 67-year-old woman with multiple myeloma and recent exposure to a person with COVID-19 developed rapidly progressive dysarthria, dysphagia, and hypoesthesia without respiratory symptoms.
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