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1999 articles

October 202624

Clinical ResearchGeriatrics

Participant Characteristics Associated With Loneliness Reduction During a Digital Social Robot Intervention Among Older Adults Living Alone in Japan: Secondary Analysis of a Randomized Controlled Trial.

This secondary analysis of a randomized controlled trial examined whether participant characteristics were associated with changes in loneliness during a digital social robot intervention among community-dwelling older…

J Med Internet ResOct 16, 2026Read summary
Clinical ResearchCardiology

Artificial intelligence-enhanced electrocardiography for predicting mortality and major adverse cardiovascular events: A systematic review and narrative synthesis.

This systematic review and narrative synthesis evaluated AI-enabled 12-lead or single-lead ECG models for predicting all-cause mortality, cardiovascular mortality, and major adverse cardiovascular events in adults.

PLoS OneOct 16, 2026Read summary
Clinical ResearchEndocrinology

Retatrutide and lipid and metabolite profiles in participants with obesity with or without type 2 diabetes.

This post hoc exploratory analysis of two randomized, placebo-controlled phase 2 trials examined fasting plasma metabolite and lipid changes with retatrutide in participants with obesity, with or without type 2…

J Clin Endocrinol MetabOct 16, 2026Read summary
Clinical ResearchPulmonology

The effects of multiregional fascial mobilization on heart rate and physiological parameters in patients with obstructive sleep apnea: A randomized controlled trial.

This randomized controlled trial assessed the acute physiological effects of a 16-minute multiregional fascial mobilization protocol in 95 men with polysomnography-confirmed moderate-to-severe obstructive sleep apnea.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchPsychiatryOpen access

Infant hippocampal and amygdala volume in an observational follow-up from a randomized clinical trial for maternal prenatal depression.

This observational follow-up examined brain volumes and later negative emotionality in 109 infants born to mothers who had participated in a randomized clinical trial of brief interpersonal psychotherapy for prenatal…

Nat CommunOct 16, 2026Read summary
Case ReportPulmonology

Life-threatening diffuse alveolar hemorrhage associated with Rhinovirus infection and the potential role of corticosteroids in immunocompetent patients: Case reports.

Two immunocompetent women, aged 85 and 70, presented with severe hypoxemia and hemoptysis or worsening dyspnea. Chest CT showed diffuse or bilateral ground-glass opacities and consolidations.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchPhysical Medicine & Rehabilitation

Effects of blood flow restriction training in adult upper-limb musculoskeletal rehabilitation: A systematic review.

This systematic review assessed the clinical effects, tolerability, and prescription of blood flow restriction training (BFRT) in adults undergoing rehabilitation for upper-limb musculoskeletal conditions.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchPsychiatryOpen access

Amygdala neurofeedback as an adjunct to residential dialectical behavior therapy for borderline personality disorder: a pilot randomized controlled trial.

This pilot randomized controlled trial tested whether real-time fMRI amygdala neurofeedback (amy-NF) adds benefit to residential dialectical behavior therapy (DBT) for people with borderline personality disorder and…

BMC PsychiatryOct 16, 2026Read summary
Case ReportNephrology

Complete remission of minimal change disease after antiviral monotherapy in a patient with immune-active chronic hepatitis B: A case report.

A 42-year-old woman presented with generalized edema, weight gain, hypoalbuminemia, and nephrotic-range proteinuria, with a urine protein-to-creatinine ratio of 4.3 and preserved renal function.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchOrthopedic Surgery

Artificial intelligence empowering the diagnosis and treatment of rotator cuff tears: A systematic review from image optimization to prognosis prediction.

This systematic review examined original studies applying artificial intelligence across the rotator cuff tear care pathway, including imaging, diagnosis, anatomical measurement, and prognosis.

Medicine (Baltimore)Oct 16, 2026Read summary
Case ReportNeurosurgery

Arthroscopic-assisted uniportal spinal surgery with bone-anchored annular repair for far lateral lumbar disc herniation: A case report.

A 50-year-old woman had refractory lumbosacral and gluteal pain followed by right L3–L4-distribution radicular pain, limiting walking to less than 20 minutes despite conservative treatment.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchEndocrinology

Efficacy and safety of imeglimin hydrochloride for metabolic dysfunction-associated steatotic liver disease with type 2 diabetes: Single-center, single-arm phase 2 (IMELD study).

This single-center, single-arm phase 2 interventional study assessed 24 weeks of imeglimin in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes.

Medicine (Baltimore)Oct 16, 2026Read summary
Case ReportGastroenterology

Acute colonic variceal bleeding treated with coil-assisted retrograde transvenous obliteration following atezolizumab-bevacizumab therapy for advanced hepatocellular carcinoma: A case report.

A 66-year-old man with alcohol-related cirrhosis and advanced hepatocellular carcinoma developed hematochezia the day after starting atezolizumab plus bevacizumab.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportOncology (Medical)Open access

Management of extravasations of enfortumab vedotin and pembrolizumab: a case report and mini review of the current literature.

A 56-year-old patient with metastatic urothelial carcinoma developed extravasation of enfortumab vedotin and pembrolizumab during the first treatment cycle after the port catheter dislocated from the cephalic vein.

J Cancer Res Clin OncolOct 16, 2026Read case
Case ReportRadiology (Diagnostic)Open access

Rare origin of the right inferior phrenic artery from the anterior inferior pancreaticoduodenal artery in a patient with hepatocellular carcinoma.

A woman in her 80s with ruptured hepatocellular carcinoma underwent emergency transcatheter arterial embolization. CT did not show the right inferior phrenic artery (RIPA) at its usual origins and suggested a source in…

Surg Radiol AnatOct 16, 2026Read case
Clinical ResearchEndocrinology

Bone phenotype of patients with genetic forms of lipodystrophy: a systematic review of literature.

This systematic review examined bone manifestations in people with genetic lipodystrophies, using human studies identified through searches of PubMed, EMBASE, and the Cochrane Library.

J Clin Endocrinol MetabOct 16, 2026Read summary
Case ReportEndocrinology

Approach to the patient with APS-1/APECED.

This article presents five cases of autoimmune polyendocrine syndrome type 1 (APS-1/APECED), a disorder caused by impaired immune tolerance and typically associated with biallelic AIRE variants.

J Clin Endocrinol MetabOct 16, 2026Read case
Clinical ResearchCardiology

Dapagliflozin After Transcatheter Aortic Valve Implantation According to Frailty in DapaTAVI Trial.

This post hoc analysis of the multicenter randomized DapaTAVI trial examined whether frailty modified dapagliflozin’s effects after transcatheter aortic valve implantation.

J Am Heart AssocOct 16, 2026Read summary
Clinical ResearchOncology (Medical)

Multicenter Phase I Study of Triapine in Combination with [177Lu]Lutetium-Dotatate in Patients with Well-Differentiated Neuroendocrine Tumors (ETCTN 10388).

This multicenter phase I dose-escalation and dose-expansion study evaluated [177Lu]lutetium-dotatate plus oral triapine in patients with well-differentiated gastroenteropancreatic neuroendocrine tumors.

Clin Cancer ResOct 15, 2026Read summary
Clinical ResearchPlastic Surgery

Optimizing Autologous Fat Grafting: A Systematic Review of Enhancement Strategies and Graft Survival.

This systematic review assessed strategies for enriching autologous fat grafts to improve graft survival, drawing on animal and clinical studies published through February 2025.

Aesthet Surg JOct 15, 2026Read summary
Clinical ResearchGastroenterology

Global Underutilization of Antiviral Therapy and Survival Outcomes in Hepatitis B Virus-Related Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis of 78 Studies and 68,243 Patients.

This systematic review and meta-analysis assessed antiviral use and its association with survival and hepatocellular carcinoma (HCC) recurrence in adults with HBV-related HCC.

J Viral HepatOct 15, 2026Read summary
Clinical ResearchInfectious Diseases

Dynamics of QuantiFERON-TB Gold Plus Results in a Large TB Preventive Treatment Trial Across 3 High-Burden HIV/TB Countries.

This longitudinal analysis of a randomized trial assessed serial QuantiFERON-TB Gold Plus (QFT-Plus) results in people with HIV enrolled in Ethiopia, Mozambique, and South Africa and assigned to three TB preventive…

J Infect DisOct 15, 2026Read summary
Case ReportCardiothoracic SurgeryOpen access

Optimization of Anticoagulation Strategy During Cardiopulmonary Bypass in Neonates with Congenital Heart Disease: A Randomized Controlled Trial.

Neonatal hemostatic immaturity complicates anticoagulation during cardiopulmonary bypass (CPB). Current practice largely follows the strategy of 400 U/kg from adult protocols, as neonatal-specific guidelines and…

Drug Des Devel TherOct 15, 2026Read case
Clinical ResearchPediatrics

Predicting neurodevelopmental delay among two-year-old infants in Northern Uganda.

This study developed and evaluated a risk-prediction model for neurodevelopmental delay among two-year-old children in Northern Uganda.

Glob Health ActionOct 15, 2026Read summary

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