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2000 articles
October 202624
Atypical presentations of Lhermitte's sign after treatment for human papillomavirus-associated oropharyngeal squamous cell carcinoma.
Two patients with human papillomavirus-associated oropharyngeal squamous cell carcinoma developed Lhermitte’s sign after chemoradiotherapy.
Facial nerve palsy and hypertension; unusual presentation of apparent mineralocorticoid excess (AME) syndrome in a paediatric patient.
A boy in early childhood presented after two days of right-sided facial palsy and was found to have severe hypertension with end-organ damage.
Idiopathic multicentric Castleman disease in an HIV-positive child.
A preadolescent girl with HIV presented with fever and unilateral facial and neck swelling. Examination showed generalised lymphadenopathy, hepatosplenomegaly, hypertension and haematuria, initially suggesting…
Fregoli syndrome in an adolescent with Moyamoya disease.
An early adolescent with known Moyamoya disease developed acute psychosis after a febrile illness accompanied by headache and vomiting.
Short- versus long-course antibiotic therapy in non-severe CAP in children: a systematic review and meta-analysis.
This systematic review and meta-analysis compared short-course (≤ 5 days) with longer (> 5 days) antibiotic therapy for non-severe community-acquired pneumonia in immunocompetent children.
Adult diagnostic reference levels in computed tomography: A systematic review and analysis of regional variability.
This systematic review examined adult computed tomography diagnostic reference levels (DRLs) across regions and examination types.
Skeletal muscle adaptation to home-based exercise in chronic kidney disease.
This randomized controlled trial examined skeletal muscle responses to a 12-week, personalized home-based exercise program in 25 people with stage 3–5 chronic kidney disease (19 assigned to exercise and 6 to usual…
Phase 2a Randomized Placebo-Controlled Human Challenge Trial of the Respiratory Syncytial Virus L-Protein Inhibitor S-337395 for Respiratory Syncytial Virus Infection.
This phase 2a, randomized, double-blind, placebo-controlled, single-centre human challenge trial assessed oral S-337395 in healthy adults aged 18–55 years inoculated with RSV-A Memphis 37b.
Survival outcomes following total intravenous versus volatile anesthesia in esophagogastric cancer surgery: a systematic review and meta-analysis.
This systematic review and meta-analysis compared total intravenous anesthesia (TIVA) with volatile anesthesia in adults undergoing curative surgery for esophageal or gastric cancer.
EACTS Expert Consensus Document on aortic valve repair and valve-sparing aortic root replacement procedures.
This EACTS Expert Consensus Document critically reviews evidence on aortic valve repair and valve-sparing aortic root replacement for aortic regurgitation and proximal thoracic aortic aneurysms across age groups.
Fractal radiomics as a virtual biopsy in glioma: A systematic review and meta-analysis of molecular status, radiogenomic associations, and survival outcomes.
This systematic review and meta-analysis assessed whether fractal-based imaging features can predict molecular alterations and outcomes in glioma.
Effectiveness of psychosocial interventions addressing informal caregivers' mental health: an umbrella systematic review with 26,481 participants.
This umbrella systematic review and random-effects meta-analysis assessed psychosocial interventions for the mental health of informal caregivers, grouped by care recipients’ clinical conditions.
Anterior ST-Segment Elevation Myocardial Infarction With Coronary Thrombosis in a Young Man with Newly Diagnosed HIV Infection and Pneumocystis jirovecii Pneumonia.
A 36-year-old man with newly diagnosed, severely immunosuppressive HIV infection and Pneumocystis jirovecii pneumonia developed an acute anterior ST-segment elevation myocardial infarction 25 days after starting…
Betaine supplementation modulates mitochondrial and redox-related adaptations in premenopausal women with overweight: a randomized controlled trial.
This randomized controlled trial examined whether eight weeks of betaine supplementation (3 g/d) affected mitochondrial-associated and redox measures in premenopausal women with overweight or obesity.
Neoadjuvant niraparib monotherapy for unresectable, homologous recombination deficiency-positive, high-grade serous ovarian cancer (NANT): a multicentre, single-arm, phase 2 trial.
This multicentre, single-arm phase 2 trial evaluated two cycles of neoadjuvant niraparib monotherapy in treatment-naïve patients with HRD-positive, advanced high-grade serous or endometrioid ovarian cancer considered…
Synbiotic supplementation leads to gut microbiome communities with functional capacity linked to better brain white matter development in preterm infants.
This secondary analysis of a randomized controlled trial examined whether daily synbiotic and nutritional supplementation could shape gut microbiome function in very and extremely preterm infants, and how those…
Capsulectomy at Explant: Rethinking Spinal Cord Stimulator Infected Generator Pocket Management in the Immunocompromised-A Case Series.
Two immunocompromised women with spinal cord stimulator (SCS) infections underwent explantation and capsulectomy. The first patient, with ulcerative colitis and psoriatic arthritis, developed granulation tissue and was…
Clinical Efficacy of 5-Aminolevulinic Acid Photodynamic Therapy Combined With Interferon Spray in Treating Common and Plantar Warts.
This randomized controlled trial evaluated the efficacy of 5-aminolevulinic acid photodynamic therapy (5-ALA-PDT) combined with recombinant human interferon alpha 2b (rhIFN-α2b) spray in 104 patients with refractory…
Finite Versus Indefinite Nucleos(t)ide Analogue Therapy in HBeAg‑Negative Chronic Hepatitis B: Meta‑Analysis of Randomized Trials.
This meta-analysis evaluated the efficacy and safety of finite versus continuous nucleos(t)ide analogue therapy in HBeAg-negative adults with chronic hepatitis B.
Digital health technologies for the prevention and management of urinary tract infections in menopausal women: A systematic review.
This systematic review synthesised evidence on digital technologies for preventing or managing urinary tract infections in menopausal women.
The effects of exercise on pulmonary function and respiratory muscle strength in patients with chronic kidney disease: a systematic review and meta-analysis.
This systematic review and meta-analysis examined experimental studies of exercise and respiratory outcomes in people with chronic kidney disease across disease stages. Thirteen studies contributed to the meta-analyses.
Immunogenicity and Safety of the Adjuvanted Respiratory Syncytial Virus Prefusion F Protein-Based Vaccine When Co-administered With the Adjuvanted Recombinant Herpes Zoster Subunit Vaccine in Adults ≥ 50 Years of Age.
This phase III, open-label, randomised trial compared co-administration of adjuvanted RSVPreF3 and recombinant zoster vaccine (RZV) with administration one month apart in adults aged ≥50 years.
Immunogenicity and Safety of Co-administration of Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine With 20-Valent Pneumococcal Conjugate Vaccine in Adults Aged ≥60 Years: A Randomized, Non-inferiority Trial.
This phase III, open-label, randomized non-inferiority trial compared concomitant versus one-month-apart administration of adjuvanted RSV prefusion F protein vaccine (RSVPreF3) and 20-valent pneumococcal conjugate…
Case report: successful use of repotrectinib in a ROS1 fusion-positive lung adenocarcinoma patient with severe renal insufficiency and prior tyrosine kinase inhibitor treatment failure.
A 69-year-old woman with advanced lung adenocarcinoma harboring an SDC4–ROS1 fusion had bilateral pulmonary lesions, mediastinal lymphadenopathy, and pleural effusions.
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