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2000 articles

October 202624

Case ReportNeurologyOpen access

Neuronal intermediate filament neurologic autoimmunity in a patient with Merkel cell carcinoma receiving pembrolizumab.

A 55-year-old woman with recurrent stage IIIA Merkel cell carcinoma developed vertigo, gait instability, dysarthria, and persistent right hemifacial and cervical spasms after her second pembrolizumab dose.

Neurol SciOct 23, 2026Read case
Case ReportOncology (Medical)Open access

Primary renal diffuse large B cell lymphoma misdiagnosed as renal cell carcinoma: A case report.

A 78-year-old man presented with 2 weeks of right flank pain radiating to the abdomen; examination was unremarkable. Tests showed mildly elevated lactate dehydrogenase and occult blood in the urine.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchOncology (Medical)Open access

Extracorporeal photopheresis for the treatment of steroid-refractory immune related adverse events from immune checkpoint inhibitor therapy: a multi-center phase Ib/II clinical trial.

This prospective, single-arm, non-randomized phase Ib/II multicentre trial evaluated extracorporeal photopheresis (ECP) for steroid-refractory immune-related adverse events (irAEs) in 30 patients receiving immune…

Nat CommunOct 23, 2026Read summary
Case ReportOrthopedic SurgeryOpen access

A case report of pulmonary embolism following endoscopic cervical discectomy in an elderly patient with cervical disc herniation.

A 65-year-old woman with cervical disc herniation, right arm pain, and multiple comorbidities underwent posterior percutaneous endoscopic cervical discectomy after conservative treatment failed.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchEndocrinology

Search for the glycated hemoglobin target minimizing mortality among people with type 2 diabetes with rare incidence of treatment-related severe hypoglycemia - Epidemiologic analysis of J-DOIT3 randomized controlled trial.

This landmark analysis of the J-DOIT3 randomized controlled trial examined associations between updated HbA1c and cardiovascular outcomes or mortality among people with type 2 diabetes, in a setting where severe…

PLoS OneOct 23, 2026Read summary
Clinical ResearchGeriatrics

Feasibility of a Co-Designed Personalized Cognitive Reablement Program Delivered via Digital Voice Assistants for Older Adults Living With Early-Stage Dementia or Mild Cognitive Impairment: Pilot Randomized Controlled Trial.

This nonblinded pilot randomized controlled trial assessed the feasibility and potential effectiveness of VOICE-COG, a personalized cognitive reablement program delivered through digital voice assistants, in adults aged…

JMIR AgingOct 23, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Prophylactic neurectomy versus nerve preservation in open inguinal hernia repair for prevention of chronic postoperative inguinal pain (CPIP): a systematic review and meta-analysis.

This systematic review and meta-analysis assessed prophylactic neurectomy versus nerve preservation in adults undergoing elective open anterior inguinal hernia repair, including 17 randomized trials.

HerniaOct 23, 2026Read summary
Clinical ResearchGastroenterology

Impact of YAQ001 on the Gut Microbiome, Permeability and Markers of Systemic Inflammation in Patients With Cirrhosis.

This double-blind randomised controlled substudy examined YAQ001’s effects on the gut microbiome and exploratory markers of gut permeability and systemic inflammation in 28 patients with cirrhosis.

Liver IntOct 23, 2026Read summary
Case ReportOncology (Medical)Open access

A case report of thyroid sarcomatoid carcinoma.

A 65-year-old man presented with fever and left-sided neck pain; examination found a hard mass in the left thyroid lobe. Ultrasound showed a hypoechoic nodule with an anterior-posterior-to-transverse diameter ratio >1…

Medicine (Baltimore)Oct 23, 2026Read case
Case ReportGeneral SurgeryOpen access

Peri-implant mucosal pressure injury (PIMPI): a proposed descriptive clinical presentation following implant-supported prosthesis delivery- a case report.

A patient developed pain and peri-implant mucosal changes after delivery of a screw-retained implant-supported fixed prosthesis.

BMC Oral HealthOct 23, 2026Read case
Clinical ResearchPediatricsOpen access

Immediate vs delayed extubation after pediatric liver transplantation: a systematic review and meta-analysis.

This systematic review and meta-analysis compared immediate operating-room extubation with delayed extubation after pediatric orthotopic liver transplantation.

Eur J PediatrOct 23, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Association between cancer cachexia and treatment-related adverse outcomes in patients with gastrointestinal cancers: a systematic review and meta-analysis.

This systematic review and meta-analysis examined cohort studies of cancer cachexia and treatment-related outcomes in patients with gastrointestinal cancers.

Support Care CancerOct 23, 2026Read summary
Case ReportOncology (Medical)Open access

Successful treatment with BrECADD in a patient with Dubin-Johnson syndrome and classic Hodgkin lymphoma: a case report.

A 26-year-old man with advanced-stage classic Hodgkin lymphoma also had Dubin–Johnson syndrome (DJS) associated with a homozygous ABCC2 variant, c.2291G>A (p.Gly764Asp).

Cancer Chemother PharmacolOct 23, 2026Read case
Clinical ResearchNeurologyOpen access

Minocycline in acute stroke: A systematic review and meta-analysis of randomized controlled trials and trial sequential analysis.

This systematic review and meta-analysis pooled randomized controlled trials comparing minocycline with control or standard care in acute ischemic and hemorrhagic stroke.

Medicine (Baltimore)Oct 23, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Effects of grip strengthening combined with scapular stabilization exercise on shoulder muscle strength and functional outcomes in individuals with subacromial pain syndrome: A randomized controlled trial.

This randomized controlled trial compared scapular stabilization exercise with the same exercise combined with grip strengthening in 36 individuals with subacromial pain syndrome (SAPS).

Medicine (Baltimore)Oct 23, 2026Read summary
Case ReportOphthalmologyOpen access

Isolated necrotizing scleritis revealing silent pulmonary granulomatosis with polyangiitis: A case report of rare diagnostic clue.

A 31-year-old man with recurrent unilateral necrotizing anterior scleritis that resisted corticosteroids and immunosuppressants had no systemic symptoms.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchHematologyOpen access

The perceptions of hematopoietic stem cell transplantation decision-making in patients with hematologic malignancies: a qualitative systematic review.

This qualitative systematic review synthesized research on how patients with hematologic malignancies perceive decisions about hematopoietic stem cell transplantation (HSCT).

Support Care CancerOct 23, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Comparative efficacy of common adjuvant treatments after resection of colorectal liver metastases: A systematic review and network meta-analysis.

This systematic review and network meta-analysis compared adjuvant strategies after resection of colorectal liver metastases, including systemic chemotherapy, hepatic arterial infusion chemotherapy (HAIC), and…

Medicine (Baltimore)Oct 23, 2026Read summary
Case ReportHematologyOpen access

Bing-Neel syndrome successfully treated with venetoclax and zanubrutinib: A case report and review of the literature.

A 66-year-old woman with Waldenström macroglobulinemia presented with headache and was diagnosed with Bing-Neel syndrome after cerebrospinal fluid examination. She received zanubrutinib with venetoclax.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchGastroenterologyOpen access

Efficacy and safety of GLP-1 receptor agonists in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH): A systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed efficacy and safety of GLP-1 receptor agonists in adults with MASLD or MASH. Nine studies involving 795 participants were included.

Medicine (Baltimore)Oct 23, 2026Read summary
Case ReportAllergy & ImmunologyOpen access

Delayed serum sickness-like reaction mimicking septic shock after antivenom therapy: A case report.

A woman in her early 60s returned about 7 days after antivenom therapy with widespread urticarial and purpuric maculopapular rash, itching, fever, vomiting, fatigue, dizziness, hypotension, and thrombocytopenia.

Medicine (Baltimore)Oct 23, 2026Read case
Case ReportOphthalmologyOpen access

Temporal inverted internal limiting membrane flap technique for a 500 μm full-thickness macular hole: A case report.

A 70-year-old woman presented with reduced vision in her left eye. Optical coherence tomography showed an hourglass-shaped full-thickness macular hole measuring 500 μm at its minimum aperture, with retinal cystic…

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchDermatologyOpen access

Fractional CO₂ laser combined with intradermal and topical platelet-rich plasma for hypertrophic scars: a randomized controlled trial.

This prospective, randomized, assessor-blinded trial compared fractional CO₂ laser plus intradermal and topical platelet-rich plasma (PRP) with laser plus saline in 120 patients with hypertrophic scars.

Lasers Med SciOct 23, 2026Read summary
Clinical ResearchObstetrics & Gynecology

The Impact of Telemedicine Interventions on Maternal and Fetal Outcomes in Women With Gestational Diabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis pooled 23 randomized controlled trials involving 3055 women with gestational diabetes to assess telemedicine and maternal and fetal outcomes.

J Med Internet ResOct 23, 2026Read summary

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