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2000 articles
October 202624
The Use of Cannabidiol in Cutaneous Wound Healing: A Systematic Review.
This qualitative systematic review assessed cannabidiol (CBD) for cutaneous wound healing, including in vivo studies and clinical trials identified through searches of seven databases. Six studies were included.
Endoscopic secondary chordae transfer and edge-to-edge repair for the treatment of asymmetric anterior leaflet prolapse.
A 59-year-old patient with Barlow’s disease presented with severe mitral regurgitation from asymmetric anterior leaflet prolapse.
Perineural versus intravenous dexmedetomidine as an adjuvant for ilioinguinal/iliohypogastric nerve block in open inguinal hernia repair: a randomised controlled trial.
This single-centre, triple-blind randomised controlled trial compared perineural, intravenous and placebo dexmedetomidine as adjuncts to an ilioinguinal/iliohypogastric nerve block in 90 adults undergoing elective open…
A comprehensive review of European clinical practice guidelines on psychological and cognitive assessment and support for cancer patients and their families.
This systematic review mapped European clinical practice guidelines and recommendations published in the preceding 15 years on psychological and cognitive assessment and support for people with cancer and their…
Camrelizumab plus chemotherapy as induction therapy followed by concurrent chemoradiotherapy and camrelizumab consolidation in limited-stage small cell lung cancer: a randomized phase II trial.
This randomized phase II trial compared a camrelizumab-based induction and consolidation strategy with induction chemotherapy followed by concurrent chemoradiotherapy (CRT) alone in previously untreated patients with…
Ramadan Fasting in Chronic Heart Failure: A Systematic Review.
This systematic review assessed clinical studies of Ramadan fasting in people with chronic heart failure. Searches of PubMed, Scopus, and Web of Science identified seven eligible studies from 137 records; most were…
Low-Volume Superior Trunk and Superficial Cervical Plexus Block With Sedation as the Sole Regional Anesthetic for Proximal Humerus Fracture Fixation in a Patient With Alzheimer Disease.
A 68-year-old woman with Alzheimer disease underwent fixation of a closed right proximal humerus fracture through a deltopectoral approach.
Vegetarian and Vegan Diets and the Risk of Hip Fracture in Adults: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed hip-fracture risk in adults following vegetarian or vegan diets compared with meat-eaters. Four cohort studies involving 529 672 participants were included.
Exploring the landscape of flagellate erythema as a rare cutaneous symptom of idiopathic inflammatory myopathy: a case series-based review.
Two patients with idiopathic inflammatory myopathy developed zebra-like flagellate erythema: one had immune-mediated necrotising myopathy and the other anti-Mi-2-positive cancer-associated myositis.
Severe growth retardation in Dent disease: a case report of a novel OCRL variant.
A 12-year-old boy with marked short stature and poor weight gain had low-molecular-weight proteinuria, haematuria, hypercalciuria and bilateral nephrocalcinosis, with normal renal function and no relevant family…
Early extracranial dissemination with prolonged survival in IDH-wildtype glioblastoma: case study and comprehensive literature review.
A 65-year-old woman with IDH-wildtype, MGMT-methylated glioblastoma presented with seizures, right hemiplegia, and expressive aphasia.
Preoperative Sedation via Cecostomy Tube in an Autistic Adolescent: A Case Report.
A 13-year-old autistic boy with a preexisting cecostomy tube for chronic constipation had previously been unable to tolerate oral or intramuscular preoperative sedation because of agitation and physical aggression.
Dietary and lifestyle quality and endometrial cancer: Incidence and survivorship outcomes-An umbrella review of systematic reviews and meta-analyses.
This umbrella review of 21 systematic reviews, including meta-analyses, assessed composite diet and lifestyle quality in relation to endometrial cancer (EC) risk and survivorship outcomes.
Intermittent or Continuous Renal-Replacement Therapy in Acute Kidney Injury.
This multicenter, open-label, randomized noninferiority trial compared intermittent hemodialysis with continuous renal-replacement therapy as initial treatment in critically ill adults with acute kidney injury and…
Continuous Glucose Monitoring in Non-Insulin-Treated Type 2 Diabetes.
This 26-week, multicenter randomized trial compared continuous glucose monitoring (CGM) with routine care in adults with type 2 diabetes not using insulin at 22 US primary care practices.
Antibiotic-Loaded Hydrogel, Calcium Bead, and Cement in Periprosthetic Joint Infection Following Hip-Knee Arthroplasty: A Systematic Review and Meta-Analysis of Commercially Available Products.
This systematic review and meta-analysis compared defensive antibacterial coating (DAC), calcium sulfate beads, and antibiotic-loaded bone cement for preventing or managing periprosthetic joint infection after total hip…
Preclinical and first-in-human evaluation of VG-3927/SAR448851, an oral small-molecule TREM2 agonist for Alzheimer's disease.
This study evaluated VG-3927, an oral, CNS-penetrant small-molecule TREM2 agonist, using preclinical models and a first-in-human randomized, double-blind, placebo-controlled phase 1 trial.
Fecal microbiota transplantation for the treatment of neurogenic rosacea: protocol of a randomized, blinded, placebo-controlled explorer study.
This publication describes the protocol for a single-center, randomized, double-blind, placebo-controlled exploratory trial of fecal microbiota transplantation (FMT) in patients with neurogenic rosacea, a phenotype…
Targeting an IL-17/IL-36 pathogenic hub in hidradenitis suppurativa with a bispecific antibody.
This phase I/II proof-of-concept clinical trial evaluated HB0043, a bispecific antibody targeting IL-17A and IL-36R, in patients with severe, tunnel-dominant Hurley Stage III hidradenitis suppurativa.
Immediate effects of spinal manipulation, exercise therapy, and open-label placebo on lifting performance and pain in individuals with chronic non-specific back pain: a motion laboratory-based crossover randomized controlled trial.
This motion-laboratory crossover randomised controlled trial examined immediate effects of spinal manipulation (SMT), exercise therapy (ET), and open-label placebo (OLP) on lifting and pain in 50 individuals with…
Association between elevated lipoprotein (a) and venous thromboembolism: A systematic review and meta-analysis.
This systematic review and meta-analysis examined observational evidence on elevated lipoprotein(a) [Lp(a)] and venous thromboembolism (VTE).
Volumetric discordance between ¹⁸F-FET-PET/MRI and MRI-based radiotherapy target volumes in high-grade glioma: a prospective pilot study (FETSMaRT).
This prospective pilot study enrolled 30 patients with WHO grade 3 or 4 high-grade glioma receiving postoperative radiotherapy.
Modified LIFT via a Lateral Approach Versus Standard LIFT for Transsphincteric Anal Fistula: A Prospective Randomized Study.
This single-center prospective randomized study compared modified ligation of the intersphincteric fistula tract (LIFT) via a lateral approach with standard LIFT in adults with MRI-confirmed transsphincteric anal…
Recurrent Primary Angiosarcoma of the Breast: Challenges and Pitfalls in a Case Report.
A patient presented with a breast lesion and skin involvement; histopathology and immunohistochemistry confirmed low- to intermediate-grade primary breast angiosarcoma.
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