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2000 articles

October 202624

Clinical ResearchGeneral SurgeryOpen access

Long-Term Effects of Biliopancreatic Diversion (BPD), Biliopancreatic Diversion with Duodenal Switch (BPD-DS), and Single Anastomosis Duodeno‑Ileal Bypass with Sleeve Gastrectomy (SADI‑S) in Patients with Obesity: A Meta-Analysis.

This systematic review and meta-analysis assessed outcomes at 10 or more years after biliopancreatic diversion (BPD), BPD with duodenal switch (BPD-DS), and single-anastomosis duodeno-ileal bypass with sleeve…

Obes SurgOct 6, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Febrile neutropenia in adults with diffuse large B-cell lymphoma receiving first-line R-CHOP-based therapy: a systematic review and meta-analysis of observational and trial evidence.

This systematic review and meta-analysis assessed febrile neutropenia (FN) in adults with diffuse large B-cell lymphoma receiving first-line R-CHOP or R-CHOP-like therapy, separating observational cohorts from clinical…

Support Care CancerOct 6, 2026Read summary
Clinical ResearchFamily Medicine

Changes in health literacy following participation in a multidisciplinary primary care intervention for people with chronic pain: a longitudinal cohort study.

This longitudinal cohort study examined changes in health literacy among 43 people with chronic non-cancer pain who completed a personalized, multidisciplinary primary care pain-management intervention.

Scand J PainOct 6, 2026Read summary
Clinical ResearchPsychiatryOpen access

Physical activity for psychological and physical well-being in menstruating individuals: an integrative review.

This integrative review synthesised qualitative, quantitative, and mixed-methods research on physical activity and psychological or physical well-being across the menstrual cycle.

BMC Womens HealthOct 6, 2026Read summary
Clinical ResearchInfectious Diseases

Efficacy and safety of switching to once-daily oral doravirine plus raltegravir in virologically suppressed people with HIV-1: a randomized, open-label, multicentre phase 2 study (DORAL).

DORAL was a multicentre, open-label, randomized phase II trial in virologically suppressed adults with HIV-1 on stable antiretroviral therapy, without prior doravirine exposure or raltegravir resistance.

J Antimicrob ChemotherOct 6, 2026Read summary
Case ReportPsychiatry

Leveraging Longitudinal DBS Recordings to Probe Pharmacological Mechanisms: Investigating the Role of Orexin Antagonists on Extended Amygdala Activity.

A patient with severe, treatment-refractory obsessive-compulsive disorder and comorbid insomnia had beta activity recorded longitudinally from the bed nucleus of the stria terminalis (BNST) using implanted deep brain…

J Vis ExpOct 6, 2026Read case
Clinical ResearchNeurology

Standardized Acupuncture Plus Modified Xiaoxuming Decoction for Acute Ischemic Stroke: A Randomized Controlled Trial.

This single-center, assessor-blinded randomized controlled trial enrolled adults with imaging-confirmed acute ischemic stroke within 72 hours and compared standard care with or without standardized acupuncture plus…

J Vis ExpOct 6, 2026Read summary
Clinical ResearchOrthopedic Surgery

Smartphone Measurement Application for Percutaneous Vertebroplasty in Osteoporotic Vertebral Compression Fractures: A Randomized Trial.

This single-center randomized controlled trial compared a LiDAR-enabled smartphone measurement application with conventional anatomical localization and C-arm verification in 43 patients with acute thoracolumbar…

J Vis ExpOct 6, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Effectiveness of Immersive and Embodied Enhancement via "Virtual Reality" on the Sustainability of Hand Hygiene Compliance:Protocol for a Randomized Controlled Trial of a School-Based Training Program.

This protocol describes a three-arm randomized controlled trial evaluating customized virtual reality (VR) handwashing education among secondary school students in Hong Kong.

JMIR Res ProtocOct 6, 2026Read summary
Clinical ResearchCardiothoracic Surgery

Minimally Invasive Versus Sternotomy in Redo Mitral Valve Surgery: Short- and Long-Term Outcomes with Meta-Regression and Time-to-Event Analysis.

This meta-analysis compared minimally invasive mitral valve surgery (MI-MVS) with sternotomy for redo surgery in adults. It included 15 studies and 3457 patients, pooling perioperative outcomes and reconstructing…

J Am Heart AssocOct 6, 2026Read summary
Clinical ResearchInfectious Diseases

A phase III randomized study: Immunogenicity and safety of a quadrivalent meningococcal conjugate vaccine in healthy adults, adolescents, and children in India and healthy adolescents and children in South Africa.

This Phase III randomized controlled trial assessed the immunogenicity and safety of a single dose of MenACYW-TT in healthy adults, adolescents, and children in India and in adolescents and children in South Africa.

VaccineOct 5, 2026Read summary
Clinical ResearchAnesthesiology

Impact of opioid-free general anesthesia with locoregional blocks during breast cancer surgery on systemic inflammatory response: results from a randomized controlled trial.

This randomized controlled trial evaluated the effects of opioid-free general anesthesia with locoregional blocks (OfGA) versus traditional opioid-based general anesthesia (GA) on postoperative inflammation in breast…

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchAnesthesiology

Assessing the completeness of safety reporting in clinical trials of regional anesthesia interventions: a registry-publication comparison systematic review.

This systematic review evaluated the completeness of adverse event (AE) reporting in interventional regional anesthesia trials registered on ClinicalTrials.gov and their corresponding publications.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchAnesthesiology

Clinical utility of randomized controlled trials of regional anesthesia for lower-extremity surgery: a systematic review.

This systematic review evaluated the clinical utility and transparency of randomized controlled trials (RCTs) on regional anesthesia (RA) for lower-extremity surgeries.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchPlastic Surgery

Feeding following cleft palate surgery: a prospective randomized clinical trial comparing suprazygomatic maxillary nerve block and greater palatine nerve block.

This randomized controlled trial evaluated the effectiveness of suprazygomatic maxillary nerve blocks (SZMNB) versus greater palatine nerve blocks (GPNB) in children aged 1-10 undergoing cleft palate surgery.

Reg Anesth Pain MedOct 5, 2026Read summary
Case ReportCardiology

Cardiac arrest revealing an occult interventricular septal hydatid cyst in a child.

An 11-year-old girl experienced sudden cardiac arrest during a biopsy of a dorsal hydatid cyst. After resuscitation, echocardiography revealed a 5.3 × 4.6 cm cyst in the interventricular septum, with CT showing liver…

Trans R Soc Trop Med HygOct 5, 2026Read case
Clinical ResearchNeurology

Objective, long-term mobility data in patients with chronic pain after lumbar spine surgery treated with spinal cord stimulation-a prospective, multicenter trial.

This multicenter clinical trial evaluated the long-term effects of spinal cord stimulation (SCS) on mobility in 50 patients with chronic pain following lumbar spine surgery.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchGastroenterology

Efficacy of Bifidobacterium animalis subsp. lactate BL-99 in relieving functional constipation: a randomized placebo-controlled clinical trial.

This randomized, double-blind, placebo-controlled trial evaluated the efficacy of Bifidobacterium animalis subsp. lactis BL-99 in 41 patients with functional constipation over 6 weeks.

Food FunctOct 5, 2026Read summary
Clinical ResearchUrology

Caudal versus penile block and urethrocutaneous fistula formation following hypospadias repair in children <2 years: a multicenter randomized clinical trial.

This multicenter randomized controlled trial evaluated the incidence of urethrocutaneous fistula (UCF) formation in children under 2 years undergoing hypospadias repair with either caudal or penile block.

Reg Anesth Pain MedOct 5, 2026Read summary
Clinical ResearchCardiology

Flavonoid-rich foods and vascular functions in healthy adults: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the effects of flavonoid-rich foods on vascular function in 561 healthy adults across 11 randomized controlled trials.

Food FunctOct 5, 2026Read summary
Case ReportEmergency Medicine

Ultrasound-Guided Disposition: Submersion Injury.

A 25-year-old male sustained an acute submersion injury due to water aspiration during snorkel training for U.S. Navy Search and Rescue Swimmer training.

J Spec Oper MedOct 5, 2026Read case
Case ReportNeurologyOpen access

Familial hypomagnesemia with secondary hypocalcemia: a novel TRPM6 mutation associated with treatment-resistant migraine in a North African family.

An 18-year-old woman from a consanguineous Moroccan family presented with lifelong hypomagnesemia and a severe migraine attack accompanied by paresthesias and muscle cramps.

Neurol SciOct 5, 2026Read case
Clinical ResearchEndocrinology

Chestnut flour-enriched bread reduces postprandial glycaemic response in healthy adults: a randomised, controlled crossover study.

This randomized controlled crossover study evaluated the impact of chestnut flour-enriched bread on postprandial glycaemic responses in fourteen healthy adults.

Food FunctOct 5, 2026Read summary
Clinical ResearchNeurologyOpen access

Systemic inflammatory response syndrome and adverse outcomes in acute intracerebral hemorrhage: a meta-analysis.

This meta-analysis evaluated the prognostic significance of systemic inflammatory response syndrome (SIRS) in 6,976 patients with acute intracerebral hemorrhage (ICH).

Neurol SciOct 5, 2026Read summary

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