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2000 articles

October 202624

Case ReportNeurology

Long-term integrative personalized medicine care in massive brainstem hemorrhage: A CARE-compliant case report.

A 48-year-old female presented with a massive pontine hemorrhage, resulting in significant functional impairment and recurrent infections.

Medicine (Baltimore)Oct 2, 2026Read case
Clinical ResearchGeneral Surgery

Antibiotic Stewardship in Nonoperative Facial Trauma: Necessary or Not?

This systematic review evaluated the effectiveness of prophylactic antibiotics in preventing infections in adults with closed, nonoperative facial fractures.

South Med JOct 2, 2026Read summary
Clinical ResearchInfectious Diseases

Participant experiences of stopping ART as part of a clinical trial; findings from a qualitative study within the RIO trial in the United Kingdom.

This qualitative study explored the experiences of 20 cisgender men living with HIV who participated in the phase 2 RIO trial, which involved analytical treatment interruptions (ATIs).

HIV Res Clin PractOct 2, 2026Read summary
Case ReportGastroenterology

Endoscopic double-layer nylon rope ligation for rescue of gastric ulcer bleeding after failed OTSC treatment: A case report (with video).

A 61-year-old man presented with hematemesis and melena due to a bleeding gastric ulcer classified as Forrest IIa. After initial treatment with an over-the-scope clip (OTSC) failed, he underwent endoscopic double-layer…

Medicine (Baltimore)Oct 2, 2026Read case
Case ReportAnesthesiology

Perioperative adrenal insufficiency presenting as refractory hypotension: A CARE-compliant article.

A 77-year-old woman undergoing lumbar fusion surgery experienced severe hypotension that did not respond to fluid resuscitation or vasopressors.

Medicine (Baltimore)Oct 2, 2026Read case
Case ReportNeurosurgeryOpen access

Endoscopic third ventriculostomy for diencephalosynapsis-related hydrocephalus in MPDZ gene syndrome: a case report and review of the literature.

A female infant with prenatally diagnosed obstructive ventriculomegaly was confirmed to have MPDZ syndrome through whole-exome sequencing.

Childs Nerv SystOct 2, 2026Read case
Clinical ResearchPsychiatry

Attachment styles and problematic involvement in potentially addictive behaviours: A systematic review and meta-analysis.

This systematic review and meta-analysis examined associations between attachment styles and problematic involvement in behaviours described as addictions, using peer-reviewed studies published before July 23rd, 2026.

Clin Psychol RevOct 2, 2026Read summary
Clinical ResearchNeurology

40 Hz transcutaneous auricular vagus nerve stimulation enhances verbal free recall in healthy adults by modulating frontal theta oscillations.

This randomized, single-blind, sham-controlled, three-arm trial examined whether 20 Hz or 40 Hz transcutaneous auricular vagus nerve stimulation (taVNS) affected verbal free recall and resting-state EEG theta activity…

NeuroimageOct 2, 2026Read summary
Clinical ResearchOrthopedic Surgery

Outcome assessment in frozen shoulder trials: A systematic review and COSMIN-informed recommendations.

This systematic review mapped outcome measures in 927 randomized controlled trials (RCTs) of frozen shoulder and conducted a COSMIN-informed appraisal of measurement-property evidence for commonly used instruments.

Complement Ther MedOct 2, 2026Read summary
Case ReportAnesthesiologyOpen access

Comparisons in Analgesic Effects Between Ultrasound-Guided Erector Spinae Plane Block and Ultrasound-Guided Modified Intercostal Nerve Block in Modified Radical Mastectomy: A Randomized Controlled Trial.

Postoperative acute pain is a common challenge after breast cancer surgery. This randomized controlled trial compared the analgesic effects of ultrasound-guided erector spinae plane block (ESPB) and modified intercostal…

Drug Des Devel TherOct 2, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Intraoperative Dexmedetomidine and Postoperative Delirium After Head and Neck Cancer Surgery with Free-Flap Reconstruction: A Secondary Analysis of a Randomized Placebo-Controlled Trial.

This delirium-focused secondary analysis of a single-centre, randomized, double-blind, placebo-controlled trial examined adults undergoing elective head and neck cancer surgery with free-flap reconstruction.

Drug Des Devel TherOct 2, 2026Read summary
Clinical ResearchHematology

Regional practice differences significantly affect the benefit of post-HCT gilteritinib in FLT3-ITD AML.

The phase 3 MORPHO trial evaluated the efficacy of gilteritinib versus placebo in post-hematopoietic cell transplantation (HCT) for FLT3-ITD AML patients.

Blood AdvOct 2, 2026Read summary
Clinical ResearchCardiologyOpen access

Efficacy and Safety of Oral Non-Statin Lipid-Lowering Therapies in Dyslipidaemia: A Systematic Review and Network Meta-Analysis.

This systematic review and network meta-analysis evaluated the efficacy and safety of oral non-statin lipid-lowering therapies in adults with dyslipidaemia.

Endocrinol Diabetes MetabOct 2, 2026Read summary
Clinical ResearchOncology (Medical)

MRD negativity by PBMCs and ctDNA confirms deep and durable responses after epcoritamab monotherapy in R/R FL.

The EPCORE NHL-1 trial evaluated the efficacy of epcoritamab, a CD3 × CD20 bispecific antibody, in patients with relapsed/refractory follicular lymphoma (FL) after at least two prior therapies.

Blood AdvOct 2, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Effects of SGLT-2 Inhibitors on Plasma Concentrations and Renal Clearance of the Risk Marker Trimethylamine-N-Oxide in Patients With Type-2 Diabetes.

This randomized controlled trial investigated the effects of SGLT-2 inhibitors empagliflozin and dapagliflozin on plasma levels and renal clearance of trimethylamine-N-oxide (TMAO) in patients with Type 2 diabetes.

Endocrinol Diabetes MetabOct 2, 2026Read summary
Clinical ResearchNephrology

Facilitators of Peer Support Among Patients With Chronic Kidney Disease: A Systematic Review and Qualitative Meta-Synthesis.

This systematic review and qualitative meta-synthesis examined facilitators of peer support among patients with chronic kidney disease (CKD).

J Ren CareOct 2, 2026Read summary
Case ReportUrologyOpen access

Isolated Prostatic Tuberculosis Coexisting with Benign Prostatic Hyperplasia: A Case Report.

A 70-year-old man presented with one month of lower urinary tract symptoms and recurrent urinary retention requiring repeated catheterization.

Int Med Case Rep JOct 2, 2026Read case
Clinical ResearchGastroenterologyOpen access

Clinical outcomes of early versus standard liver transplantation in patients with alcohol-related liver disease: a meta-analysis.

This meta-analysis compared early and standard liver transplantation in patients with alcohol-related liver disease. It included 12 studies and 2323 patients.

Langenbecks Arch SurgOct 2, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Platelet-rich plasma versus corticosteroid injections for facet and sacroiliac joint pain: a systematic review and meta-analysis with trial sequential analysis.

This systematic review and meta-analysis evaluated the efficacy of platelet-rich plasma (PRP) versus corticosteroid injections for treating facet and sacroiliac joint pain in 392 patients.

Pain MedOct 1, 2026Read summary
Clinical ResearchPediatricsOpen access

Family-Centered Child Obesity Treatment: The TEAM UP Randomized Clinical Trial.

This pragmatic randomized clinical trial evaluated the effectiveness of enhanced standard of care with family-based behavioral treatment (ESOC+FBT) compared to enhanced standard of care alone (ESOC) in reducing percent…

JAMA PediatrOct 1, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Bone Accrual During Puberty Suppression and Gender-Affirming Therapy in Transgender Adolescents: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated bone mineral density (BMD) and z scores in transgender adolescents undergoing gonadotropin-releasing hormone agonist (GnRHa) therapy followed by gender-affirming…

JAMA PediatrOct 1, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Health Communication and Stepped Reminders Interventions for Lung Cancer Screening: A Randomized Clinical Trial.

This randomized clinical trial evaluated two patient-centered interventions aimed at increasing adherence to annual lung cancer screening among patients with normal findings.

JAMA Intern MedOct 1, 2026Read summary
Clinical ResearchPediatricsOpen access

Erythropoietin for Neonatal Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.

This multicenter randomized clinical trial evaluated the efficacy of erythropoietin (EPO) as an adjunct to therapeutic hypothermia in infants with moderate to severe hypoxic-ischemic encephalopathy (HIE).

JAMA PediatrOct 1, 2026Read summary
Clinical ResearchPulmonologyOpen access

Autonomous Oxygen Titration for Maintaining Normoxemia in Acutely Ill Adults: The SAVE-O2 AI Randomized Clinical Trial.

The SAVE-O2 AI randomized clinical trial evaluated the effectiveness of autonomous oxygen titration in maintaining normoxemia in acutely ill adults receiving supplemental oxygen.

JAMA Intern MedOct 1, 2026Read summary

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