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2000 articles
October 202624
Long-Term Safety and Efficacy of Dazukibart in Dermatomyositis: Combined Phase II Results From Double-Blind and Open-Label Extension Studies.
This study evaluated the long-term safety and efficacy of dazukibart, an antiinterferon β monoclonal antibody, in adults with moderate-to-severe dermatomyositis through a combined Phase II randomized controlled trial…
Three versus six weeks of corticosteroids for mild immune-related pneumonitis: a randomized trial.
This randomized controlled trial evaluated the efficacy of a 3-week versus a 6-week corticosteroid taper in patients with mild immune-related pneumonitis.
Advanced therapies for extraintestinal manifestations of IBD: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of advanced therapies (ATs) for extraintestinal manifestations (EIMs) in patients with inflammatory bowel diseases (IBD).
Immersive Virtual Reality and Anxiety, Nausea, and Vomiting in Children With Cancer: An RCT.
This randomized controlled trial evaluated the impact of immersive virtual reality (IVR) on anxiety, anticipatory nausea, and chemotherapy-induced nausea and vomiting (CINV) in pediatric cancer patients aged 6-12…
Continuous Renal Replacement Therapy for Cytokine Storm in Diabetic Kawasaki Shock Syndrome.
A 3-year, 10-month-old boy with poorly controlled type 1 diabetes and autoimmune thyroiditis presented with Kawasaki disease shock syndrome and diabetic ketoacidosis.
Early-life liquefied petroleum gas cooking intervention and lung function in Guatemalan children: a randomized clinical trial.
This randomized clinical trial assessed the impact of an early-life liquefied petroleum gas cooking intervention on lung function in Guatemalan children.
Measurement Properties of Delirium Tools in Pediatric Intensive Care: A Systematic Review.
This systematic review evaluated the measurement properties of pediatric delirium tools in intensive care, analyzing 41 studies.
Factors influencing access to green health prescribing in primary care for older adults - a qualitative systematic review.
This systematic review examined barriers and enablers to green health prescribing (GHP) for older adults with long-term conditions.
Exceptional and Durable Response to Selpercatinib in a Patient with Apparently RET -Negative, HRAS -, and NF1 -Mutated Metastatic Medullary Thyroid Carcinoma.
A 50-year-old woman presented with rapidly progressive medullary thyroid carcinoma (Ki-67 30%) and extensive liver and bone metastases.
Network meta-analysis of robotic ventral and incisional hernia repair techniques: intraperitoneal, preperitoneal, retromuscular, and sublay approaches.
This network meta-analysis evaluated the efficacy and safety of various robotic ventral and incisional hernia repair techniques in 9,348 adults.
Pediatric Literacy Promotion for Latino Families by Texts and Referrals: A 3-Arm RCT.
This randomized controlled trial evaluated two strategies to enhance literacy promotion among 630 Latino caregiver-infant dyads.
Hereditary TTP and Hemolytic Anemia in Newborns.
This case report discusses three siblings diagnosed with hereditary thrombotic thrombocytopenic purpura (hTTP) due to ADAMTS13 deficiency, presenting with severe jaundice at birth.
Behavioral Interventions in Pediatric Type 1 Diabetes Management: An Updated Meta-Analysis.
This updated meta-analysis evaluated the impact of behavioral interventions on hemoglobin A1C (HbA1C) in youths with type 1 diabetes (T1D) across 46 randomized controlled trials.
Effects of high-dose supplemental oxygen therapy on pulmonary haemodynamics at 3250 m in high-altitude residents at risk for pulmonary hypertension.
This open-label, non-randomised trial investigated the effects of high-dose supplemental oxygen therapy (SOT) on pulmonary haemodynamics in Kyrgyz highlanders at 3250 m with elevated systolic pulmonary artery pressure…
Meta-analysis of Asymptomatic Monkeypox Virus Prevalence in Nonendemic Regions, 2022-2024.
This meta-analysis examined the prevalence of asymptomatic monkeypox virus (MPXV) detections in nonendemic regions from May 2022 to September 2024.
Toripalimab consolidation after chemoradiotherapy in limited-stage small cell lung cancer: a phase II, randomized controlled study (GASTO-1052A).
This phase II randomized controlled trial evaluated the efficacy and safety of toripalimab consolidation after chemoradiotherapy in patients with limited-stage small cell lung cancer (LS-SCLC).
A Systematic Review and Meta-Analysis of the Prevention and Management of Pediatric Urinary Tract Infection and Suspected Urinary Tract Infection: Technical Report.
This systematic review and meta-analysis evaluated management strategies for pediatric urinary tract infections (UTIs) in children without known anatomic anomalies, including antibiotic duration and route, and the use…
A Systematic Review and Meta-Analysis of the Role of Ultrasonography for the Diagnosis of Vesicoureteral Reflux in Pediatric Patients Following Urinary Tract Infections: Technical Report.
This systematic review and meta-analysis evaluated the diagnostic accuracy of renal and bladder ultrasonography (RBUS) for detecting vesicoureteral reflux (VUR) in pediatric patients post-urinary tract infection (UTI).
Buruli Ulcer Acquired From Ringtail Possum Rescue.
A patient presented with a Buruli ulcer, which was likely acquired from a scratch by a ringtail possum during a rescue attempt. This case highlights a newly recognized transmission route for Buruli ulcer.
Toxin-induced coagulopathy following a MacMahon viper bite.
A patient presented with a MacMahon viper bite, experiencing significant local envenomation, hypotension, and syncope. Laboratory tests showed rapid thrombocytopenia and impaired haemostatic function.
Enhanced recovery after colorectal surgery in patients with inflammatory bowel disease to reduce hospital length of stay: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of enhanced recovery after surgery (ERAS) protocols on adult patients with inflammatory bowel disease (IBD).
Systematic Review and Meta-analysis of Group B Streptococcus Rectovaginal Colonization Rates and Serotype Distribution among Pregnant Women, Asia-Pacific Region, 2014-2025.
This systematic review and meta-analysis examined group B Streptococcus (GBS) rectovaginal colonization rates among 978,150 pregnant women in the Asia-Pacific region.
Felzartamab plus lenalidomide-dexamethasone versus lenalidomide-dexamethasone for relapsed or refractory multiple myeloma: an open-label, parallel-controlled, randomised, phase 3 trial.
This phase 3 randomized trial evaluated the efficacy of felzartamab combined with lenalidomide-dexamethasone versus lenalidomide-dexamethasone alone in Chinese patients with relapsed or refractory multiple myeloma.
Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults.
This Phase I randomized controlled trial evaluated the pharmacokinetics, immunogenicity, and safety of REGN17092, a modified YTE antibody targeting SARS-CoV-2, in 40 healthy adults.
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