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1297 articles
October 202624
Vascular health after quitting smoking or switching to e-cigarette use: a systematic review of prospective studies with GRADE assessment.
This systematic review assessed prospective evidence on vascular function after smoking cessation or switching to exclusive e-cigarette use among adult smokers.
Postoperative Pain Treatment After Pancreatic Surgery: A Systematic Review With Meta-Analyses and Trial Sequential Analyses.
This PROSPERO-registered systematic review and meta-analysis examined postoperative analgesia after total pancreatectomy, pancreaticoduodenectomy, and distal pancreatectomy.
Efficacy and Safety of Ushaq Capsule as Adjunctive Therapy in Patients With Lumbar Radiculopathy: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial at Imam Khomeini Hospital, Tehran, Iran.
This double-blind, randomized, placebo-controlled trial evaluated Ushaq capsules as adjunctive therapy in 68 patients with lumbar radiculopathy.
Association between chronic opioid exposure and cardiovascular disease: a systematic review and meta-analysis.
This systematic review and meta-analysis examined associations between chronic opioid exposure—including opium use, opioid use disorder, and prescription opioids—and cardiovascular disease in human studies.
Ergonomic interventions for treating work-related complaints of the arm, neck or shoulder in adults.
This Cochrane systematic review and meta-analysis assessed ergonomic interventions for work-related arm, neck or shoulder complaints (CANS) in adults.
A Randomized, Double-Blind, Placebo-Controlled Study of the PD-1 Inhibitor Cetrelimab in Chronic Hepatitis B.
This randomized, double-blind, placebo-controlled study assessed the safety, activity and pharmacokinetics of a single low dose of the PD-1 inhibitor cetrelimab in adults with chronic hepatitis B virologically…
Combining Cognitive Training and Brain Stimulation: A Novel Approach to Address Disordered Eating and Antipsychotic-Induced Weight Gain in People With Severe Mental Illness.
This double-blind, parallel-group, sham-controlled randomised trial assessed the feasibility of combining Approach Bias Modification Training (ABMT) with real or sham transcranial direct current stimulation (tDCS) in…
Haemodynamic and Respiratory Effects of Dexmedetomidine as an Adjuvant to Oxycodone Patient-Controlled Analgesia After Lumbar Spinal Fusion: A Post Hoc Analysis of the DoseRespDex Randomised Controlled Trial.
This post hoc analysis of a randomised, double-blind, placebo-controlled trial examined haemodynamic and respiratory effects of dexmedetomidine added to oxycodone patient-controlled analgesia in 98 adults undergoing…
Efficacy and Safety of Apixaban Thromboprophylaxis According to Baseline Chemotherapy Class in High-Risk Ambulatory Cancer Patients: A Post Hoc Analysis of the AVERT Trial.
This post hoc analysis of the randomized, double-blind AVERT trial examined apixaban thromboprophylaxis by baseline chemotherapy class in 563 ambulatory patients with cancer starting chemotherapy.
Zamtocabtagene autoleucel, a tandem CD20-CD19-directed CAR T-cell therapy, for second line treatment of large B-cell lymphoma in patients ineligible for transplantation (DALY 2-EU): primary analysis of an open-label, multicentre, randomised phase 2 study.
DALY 2-EU was an open-label, multicentre, randomised phase 2 trial comparing tandem CD20-CD19-directed zamtocabtagene autoleucel (zamto-cel) with R-GemOx in adults with second-line relapsed or refractory large B-cell…
Assessing stigma and perceptions of respectful care in Malawi's index case testing program: Findings from a cluster randomized controlled trial.
This cluster randomized controlled trial assessed whether enhanced stigma-reduction training improved healthcare worker (HCW) attitudes and client experiences in Malawi’s HIV index case testing program.
Comparative effectiveness of three splints for rehabilitation after finger flexor tendon repair (FIRST): randomised controlled trial.
The FIRST pragmatic, multicentre randomised trial compared forearm-based long, Manchester short, and relative motion flexion mini splints for rehabilitation after primary zone 1 or 2 finger flexor tendon repair.
Four weeks of isometric handgrip training results in lower awake ambulatory blood pressure compared with control: a randomized clinical trial.
This randomized controlled trial compared handgrip and knee-extension isometric training with control in 67 adults with controlled hypertension receiving antihypertensive medication.
Air versus supplemental oxygen for resuscitation of term or late preterm infants at birth.
This Cochrane systematic review and meta-analysis assessed randomised and quasi-randomised trials comparing air with supplemental oxygen for resuscitation at birth in term and late preterm infants needing respiratory…
Robot-assisted versus open partial nephrectomy in patients with a solitary kidney: a systematic review and meta-analysis of perioperative and functional outcomes.
This systematic review and meta-analysis compared robot-assisted partial nephrectomy (RAPN) with open partial nephrectomy (OPN) for tumors in a solitary kidney.
Associating liver partition and portal vein ligation for staged hepatectomy procedure versus conventional two-stage hepatectomy for colorectal liver metastasis.
This Cochrane systematic review and meta-analysis assessed ALPPS versus conventional two-stage hepatectomy in adults with colorectal liver metastases and an estimated future liver remnant below 30% of total liver…
Body image distress in women and men with advanced pancreatic cancer approaching death - post-hoc analyses from the MISTRAL-trial.
This post-hoc analysis of data from the MISTRAL trial examined changes in body image distress and weight worries among 125 women and men with pancreatic cancer during the six months before death.
Is resistance training effective to increase BDNF in multiple sclerosis? An updated systematic review and meta-analysis of isolated interventions.
This systematic review and meta-analysis examined whether isolated resistance training (RT) affects peripheral brain-derived neurotrophic factor (BDNF) in people with multiple sclerosis (MS).
Erector spinae plane block added to intercostal nerve block versus intercostal nerve block alone for postoperative analgesia in video-assisted thoracoscopic surgery: A randomized controlled trial.
This prospective, randomized controlled trial compared surgical intercostal nerve block (INB) alone with INB plus single-injection erector spinae plane block (ESPB) in 60 adults undergoing elective three-port…
Next-Generation Bed Nets to Control Malaria in Côte d'Ivoire.
This cluster-randomized clinical trial compared pyrethroid-only long-lasting insecticidal nets with piperonyl butoxide-pyrethroid (PBO-py) and chlorfenapyr-pyrethroid (CFP-py) nets in villages in Côte d'Ivoire.
Revascularization of Asymptomatic Carotid Artery Stenosis: Cognitive Results of the CREST-2 Randomized Trials.
This prespecified cognitive-outcomes analysis of the multicentre, randomised CREST-2 trials assessed patients aged 35 years or older with at least 70% asymptomatic carotid stenosis.
Measles transmission-related epidemiological parameter estimates: a systematic review and meta-analysis.
This systematic review and meta-analysis synthesized English- and French-language primary studies reporting measles transmission-related epidemiological parameters, identified through 14 May 2024.
Effectiveness of Wrist-Worn Wearable-Guided Cardiac Rehabilitation Delivered Through Fully Remote or Hybrid Programs in Patients With Cardiovascular Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis assessed randomized trials of wrist-worn wearable-guided cardiac rehabilitation delivered remotely or in hybrid formats during phase II or III rehabilitation for adults with…
E-Cigarettes with and without Behavioral Support for Smoking Cessation.
This randomized controlled trial compared an e-cigarette starter pack alone, the starter pack plus multisession telephone-based behavioral support, and automated supportive messages among people who smoked and were…
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