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2000 articles

October 202624

Clinical ResearchPsychiatry

Psychoeducation for posttraumatic stress disorder in adults: a systematic review of formats and delivery approaches.

This systematic review synthesized randomized controlled trials of psychoeducation for adults with PTSD, including interventions delivered alone or as a primary component.

Eur J PsychotraumatolOct 23, 2026Read summary
Case ReportOncology (Medical)Open access

Primary renal diffuse large B cell lymphoma misdiagnosed as renal cell carcinoma: A case report.

A 78-year-old man presented with 2 weeks of right flank pain radiating to the abdomen; examination was unremarkable. Tests showed mildly elevated lactate dehydrogenase and occult blood in the urine.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchOncology (Medical)Open access

Extracorporeal photopheresis for the treatment of steroid-refractory immune related adverse events from immune checkpoint inhibitor therapy: a multi-center phase Ib/II clinical trial.

This prospective, single-arm, non-randomized phase Ib/II multicentre trial evaluated extracorporeal photopheresis (ECP) for steroid-refractory immune-related adverse events (irAEs) in 30 patients receiving immune…

Nat CommunOct 23, 2026Read summary
Case ReportInfectious DiseasesOpen access

Pulmonary infection caused by Nocardia cyriacigeorgica and influenza A virus coinfection in an immunocompetent patient: A case report.

A 60-year-old immunocompetent man without reported underlying pulmonary disease presented with recurrent cough and sputum production over 5 months, worsening respiratory symptoms, and recent fever.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchGeriatrics

Feasibility of a Co-Designed Personalized Cognitive Reablement Program Delivered via Digital Voice Assistants for Older Adults Living With Early-Stage Dementia or Mild Cognitive Impairment: Pilot Randomized Controlled Trial.

This nonblinded pilot randomized controlled trial assessed the feasibility and potential effectiveness of VOICE-COG, a personalized cognitive reablement program delivered through digital voice assistants, in adults aged…

JMIR AgingOct 23, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

The entorhinal cortex atrophy score for diagnostic distinction between phases of the Alzheimer's disease continuum.

This systematic review assessed the Entorhinal Cortex Atrophy (ERICA) visual score for distinguishing subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer’s disease (AD) dementia.

Arq NeuropsiquiatrOct 23, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Comparative efficacy of common adjuvant treatments after resection of colorectal liver metastases: A systematic review and network meta-analysis.

This systematic review and network meta-analysis compared adjuvant strategies after resection of colorectal liver metastases, including systemic chemotherapy, hepatic arterial infusion chemotherapy (HAIC), and…

Medicine (Baltimore)Oct 23, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Prophylactic neurectomy versus nerve preservation in open inguinal hernia repair for prevention of chronic postoperative inguinal pain (CPIP): a systematic review and meta-analysis.

This systematic review and meta-analysis assessed prophylactic neurectomy versus nerve preservation in adults undergoing elective open anterior inguinal hernia repair, including 17 randomized trials.

HerniaOct 23, 2026Read summary
Clinical ResearchObstetrics & Gynecology

The Impact of Telemedicine Interventions on Maternal and Fetal Outcomes in Women With Gestational Diabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis pooled 23 randomized controlled trials involving 3055 women with gestational diabetes to assess telemedicine and maternal and fetal outcomes.

J Med Internet ResOct 23, 2026Read summary
Clinical ResearchEndocrinology

Search for the glycated hemoglobin target minimizing mortality among people with type 2 diabetes with rare incidence of treatment-related severe hypoglycemia - Epidemiologic analysis of J-DOIT3 randomized controlled trial.

This landmark analysis of the J-DOIT3 randomized controlled trial examined associations between updated HbA1c and cardiovascular outcomes or mortality among people with type 2 diabetes, in a setting where severe…

PLoS OneOct 23, 2026Read summary
Clinical ResearchNeurologyOpen access

Lesion Water Content on CT Predicts 12-Month Outcome and Modifies Thrombectomy Effect in Large-Core Stroke-A Secondary Analysis of the TENSION Trial.

This secondary analysis of the randomized TENSION trial examined whether CT-derived net water uptake (NWU) predicts 12-month outcomes and modifies thrombectomy effects in 198 patients with large-core ischemic stroke.

Transl Stroke ResOct 23, 2026Read summary
Clinical ResearchGeriatrics

A Methodological Framework for a Large Language Model Virtual Companion for Older Adults at Risk of Social Isolation.

This paper presents a methodological framework for developing and evaluating a large language model (LLM)-driven virtual companion for older adults at risk of social isolation.

J Vis ExpOct 23, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Effect of Danggui Buxue Medicinal Diet on cancer-related fatigue in anemic colon cancer patients undergoing chemotherapy: A randomized controlled trial (CONSORT-compliant).

This randomized controlled trial evaluated a 21-day Danggui Buxue Medicinal Diet alongside standard care in patients with chemotherapy-induced anemia after colon cancer surgery.

Medicine (Baltimore)Oct 23, 2026Read summary
Clinical ResearchGastroenterology

Impact of YAQ001 on the Gut Microbiome, Permeability and Markers of Systemic Inflammation in Patients With Cirrhosis.

This double-blind randomised controlled substudy examined YAQ001’s effects on the gut microbiome and exploratory markers of gut permeability and systemic inflammation in 28 patients with cirrhosis.

Liver IntOct 23, 2026Read summary
Case ReportUrology

Extending the Graft Harvesting Area in Severe Penoscrotal Hypospadias: The Rainbow Technique.

A 2-year-old with severe penoscrotal hypospadias, a scrotal meatus, bifid scrotum, and chordee exceeding 90° underwent first-stage reconstruction.

Int Braz J UrolOct 23, 2026Read case
Case ReportPlastic SurgeryOpen access

Staged limb salvage after an infected full-thickness shoulder-girdle flame burn with osteoarticular exposure in an elderly patient: A case report with 3.5-year follow-up.

A 73-year-old woman with diabetes, hypertension, and cachexia presented about 3 weeks after a flame burn with an extensive infected wound from the neck base to the distal left arm.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchGeriatricsOpen access

Systematic review and meta-analysis of risk factors for oral frailty.

This systematic review and meta-analysis examined factors associated with oral frailty across 14 studies involving 12,297 participants, of whom 4,540 had oral frailty.

Medicine (Baltimore)Oct 23, 2026Read summary
Case ReportInfectious Diseases

Streptococcus constellatus-Associated Lemierre Syndrome Presenting With Cavitating Septic Pulmonary Emboli Managed by Video-Assisted Thoracoscopy.

A previously healthy 25-year-old man presented with a week of dyspnea, productive cough, fever, and hemoptysis, with severe hypoxemia and respiratory distress.

Am J Case RepOct 23, 2026Read case
Case ReportOrthopedic SurgeryOpen access

Integrated tendon repair and staged skin grafting for a severe forearm degloving injury: A case report from a low-resource setting.

A 21-year-old right-handed man presented two hours after a road traffic collision with extensive degloving of the right forearm, wrist, and dorsal thumb.

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchOncology (Medical)Open access

Protective effect of N-acetylcysteine on oxaliplatin-induced peripheral neuropathy in colorectal cancer: a randomized controlled trial.

This randomized controlled trial evaluated oral N-acetylcysteine (NAC) for preventing oxaliplatin-induced peripheral neuropathy in 46 patients with stage III or high-risk stage II colorectal cancer receiving adjuvant…

Cancer Chemother PharmacolOct 23, 2026Read summary
Clinical ResearchNeurologyOpen access

Minocycline in acute stroke: A systematic review and meta-analysis of randomized controlled trials and trial sequential analysis.

This systematic review and meta-analysis pooled randomized controlled trials comparing minocycline with control or standard care in acute ischemic and hemorrhagic stroke.

Medicine (Baltimore)Oct 23, 2026Read summary
Case ReportOncology (Medical)Open access

A case report of thyroid sarcomatoid carcinoma.

A 65-year-old man presented with fever and left-sided neck pain; examination found a hard mass in the left thyroid lobe. Ultrasound showed a hypoechoic nodule with an anterior-posterior-to-transverse diameter ratio >1…

Medicine (Baltimore)Oct 23, 2026Read case
Clinical ResearchDermatologyOpen access

Fractional CO₂ laser combined with intradermal and topical platelet-rich plasma for hypertrophic scars: a randomized controlled trial.

This prospective, randomized, assessor-blinded trial compared fractional CO₂ laser plus intradermal and topical platelet-rich plasma (PRP) with laser plus saline in 120 patients with hypertrophic scars.

Lasers Med SciOct 23, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Skeletal effects of GLP-1 receptor agonist therapy in adults with overweight or obesity: a systematic review.

This systematic review examined randomized evidence on bone mineral density (BMD) and bone-turnover markers in adults with overweight or obesity receiving GLP-1 receptor agonists.

Arch OsteoporosOct 23, 2026Read summary

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