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2000 articles
October 202624
Effectiveness and safety of atorvastatin/ ezetimibe fixed-dose combination in hypercholesterolemia: a systematic review and network meta-analysis.
This systematic review and network meta-analysis compared atorvastatin alone with atorvastatin/ezetimibe free-equivalent and fixed-dose combinations in people with hypercholesterolemia.
A multifaceted intervention to increase bystander CPR rates after out-of-hospital cardiac arrest in France: a stepped-wedge, cluster-randomised, controlled trial.
This stepped-wedge, cluster-randomised controlled trial assessed a coordinated intervention to increase bystander CPR before EMS arrival among adults with non-traumatic out-of-hospital cardiac arrest in France.
From Alert to Action: Electronic Practice Advisory Improves DSMES Referrals Over 18 Months.
This cluster-randomized controlled trial in primary care practices in central North Carolina tested whether an electronic health record best practice advisory (BPA) increased referrals to diabetes self-management…
Ruxolitinib for the treatment of pediatric acute and chronic steroid-refractory graft-versus-host disease: Efficacy, safety, and outcomes.
This single-center retrospective study assessed ruxolitinib in children under 18 years with steroid-refractory graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
5-Aminolevulinic acid-based photodynamic therapy used as a long-term management approach for refractory lichen sclerosus.
A 37-year-old man with more than 10 years of genital lichen sclerosus had recurrence after surgical resection, which left permanent anatomical deformity.
Prophylactic Low-Dose Esketamine for Prevention of Intraoperative Penile Erection During Ureteroscopic Surgery Under General Anesthesia: A Randomized, Double-Blind, Placebo-Controlled Trial.
Intraoperative penile erection (IPE) during ureteroscopic surgery may interrupt surgical procedures and increase the risk of urethral injury.
The Improvement in the Clinical Management of Patients Undergoing Palliative Care After Training the Primary Care Team by a Specialized Team: A Systematic Review.
This systematic review assessed whether palliative care training for healthcare professionals in primary care improves symptom assessment and clinical management. Eight studies with varied designs were included.
Thermographic outcomes of auricular laser acupuncture and auricular seed acupressure in older adults with chronic shoulder pain: an exploratory nonrandomized, nonconcurrent comparison.
This exploratory, open-label, nonrandomized comparison studied 20 adults aged 60–90 years with chronic shoulder pain, allocated by order of entry to auricular laser acupuncture or seed acupressure.
Bronchial Thermoplasty in Severe Asthma: Bridging Randomised and Real-World Evidence: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed bronchial thermoplasty (BT) efficacy and safety in adults with severe uncontrolled asthma, analysing randomised controlled trials (RCTs) separately from observational…
EFFICACY AND SAFETY OF SUBTHRESHOLD LASER IN PATIENTS WITH ACUTE CENTRAL SEROUS CHORIORETINOPATHY: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed the efficacy and safety of subthreshold laser for acute central serous chorioretinopathy (CSC), including six randomized controlled trials with 401 participants.
Acetic acid chromoendoscopy for detection of neoplastic Barrett's oesophagus: stepped wedge cluster randomised controlled trial (ACID-trial).
This prospective, open-label, stepped-wedge cluster randomised trial assessed whether acetic acid chromoendoscopy (AAC) improved detection of dysplasia or oesophageal adenocarcinoma during Barrett’s oesophagus…
Evaluating Improvement in Pain and Sensory Function When Using High-Frequency (10-kHz) Spinal Cord Stimulation in Individuals With Painful Diabetic Neuropathy: A Multicenter Randomized Controlled Trial (PDN-Sensory).
The multicenter randomized controlled PDN-Sensory trial evaluated 10-kHz spinal cord stimulation (SCS) plus conventional medical management (CMM) versus CMM alone in people with painful diabetic neuropathy.
Interventions to increase participation in lung cancer screening programmes: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed interventions to improve informed choice and participation in low-dose CT lung cancer screening.
Systematic review and meta-analysis of mesh versus suture repairs of small umbilical hernias (≤ 2 cm).
This systematic review and meta-analysis compared mesh with suture repair for small umbilical hernias (defects ≤ 2 cm). The primary outcome was postoperative recurrence; secondary outcomes included complications and…
Direct and indirect entomological efficacy of Targeted Indoor Residual Spraying against Aedes aegypti in Iquitos, Peru.
This entomological cluster-randomized controlled trial in Iquitos, Peru, compared targeted indoor residual spraying (TIRS) with standard Ministry of Health vector-control activities.
Additional Functional Exercise Training Improves Knee Recovery After Meniscus Repair: A Randomized Controlled Trial.
This prospective randomized controlled trial assessed whether functional exercise training (FET) added to conventional rehabilitation improves recovery after meniscus repair.
Disease-free survival and overall survival after neoadjuvant immunotherapy in mismatch repair-deficient colon cancer in the Netherlands: results of the single-arm, multicentre, phase 2, NICHE-2 trial.
This single-arm, multicentre phase 2 trial assessed neoadjuvant ipilimumab plus nivolumab followed by surgery in previously untreated patients with resectable stage 2 or 3 mismatch repair-deficient colon cancer.
METASTATIC UROTHELIAL CARCINOMA OF THE BLADDER TO THE RETINA: A CLINICOPATHOLOGIC CORRELATION AND REVIEW OF THE LITERATURE.
A patient with urothelial carcinoma of the bladder had a large yellow-white lesion in the superotemporal retina of the left eye.
The Effect of Obesity on the α-Cell Response to Hyperglycemia in the Presence of Amino Acids.
This randomized, two-occasion study examined how amino acids affect glucagon suppression during graded glucose infusion in lean participants and participants with obesity, with or without hepatic steatosis.
A Systematic Review of Complications Following Elective Foot and Ankle Surgery.
This systematic review synthesized complication profiles and risk factors in adults undergoing elective foot and ankle surgery.
The impact of recreational beach tennis associated with nutritional counseling on cardiometabolic risk factors in adolescents: a randomized clinical trial.
This 12-week randomized clinical trial compared recreational beach tennis alone with beach tennis plus nutritional counseling in 40 adolescents aged 11–14 years.
Optimizing exercise prescriptions for older adults with mild cognitive impairment: a dose-response network meta-analysis of modality-dose combinations on executive function.
This Bayesian dose-response network meta-analysis synthesized randomized controlled trials of repeated exercise programmes in adults aged 60 years or older with mild cognitive impairment.
Teclistamab Induced a Profound Hematologic Response in Light Chain Deposition Disease With Probable Cardiac Involvement.
A 63-year-old man had κ-light chain deposition disease involving the kidneys, with probable cardiac involvement. After an initial response to daratumumab-pomalidomide-dexamethasone, he developed hematologic relapse.
Placebo effects of caffeine on sport performance: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether deceptively describing a placebo as caffeine affects sport performance in healthy adults.
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