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2000 articles

October 202624

Case ReportRheumatologyOpen access

Tocilizumab for active rheumatoid arthritis in a patient with concomitant primary biliary cholangitis: a case based review.

A 59-year-old woman presented with highly active, seropositive rheumatoid arthritis and marked cholestatic biochemical activity. Evaluation identified active primary biliary cholangitis without advanced liver fibrosis.

Rheumatol IntOct 17, 2026Read case
Clinical ResearchNeurosurgeryOpen access

Symptom duration and postoperative outcomes in degenerative cervical myelopathy: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether symptom duration is associated with outcomes after surgery for degenerative cervical myelopathy (DCM).

Neurosurg RevOct 17, 2026Read summary
Case ReportNeurologyOpen access

Co-existence of CLCN1 and DNM2 variants in a phenotype overlapping myotonia and myopathy.

An Iranian family was evaluated for a phenotype combining severe myotonia and myopathic features. The index patient had clinical and electrical myotonia, with myopathic changes on electromyography.

Mol Biol RepOct 17, 2026Read case
Clinical ResearchRadiology (Diagnostic)Open access

Atypical Stafne bone defect: a systematic review.

This systematic review synthesized English-language case reports and case series of atypically located Stafne bone defects (SBDs), searching four databases through January 2026.

Clin Oral InvestigOct 17, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Effectiveness of local ablative therapy combined with first-line tyrosine kinase inhibitors in epidermal growth factor receptor-mutated oligometastatic non-small cell lung cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed local ablative therapy (LAT) plus first-line tyrosine kinase inhibitors (TKIs) versus TKI alone in patients with EGFR-mutated oligometastatic non-small cell lung cancer.

Clin Exp MetastasisOct 17, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Digital supportive care in prostate cancer: a systematic review.

This systematic review synthesised evidence on the perspectives and requirements of people affected by prostate cancer for patient-facing digital supportive care.

Support Care CancerOct 17, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Vacuum-Assisted Breast Biopsy and Excision for Breast Lesions: A Systematic Review and Meta-analysis of Malignant Upgrade in B3 Lesions.

This systematic review and meta-analysis examined malignant upgrade in B3 breast lesions assessed through diagnostic vacuum-assisted biopsy (VAB/VABB) or second-line vacuum-assisted excision (VAE).

J Vis ExpOct 16, 2026Read summary
Case ReportEmergency MedicineOpen access

Seizures Secondary to Aconitum Plant Poisoning: a case report.

A 53-year-old man developed ventricular tachycardia progressing to ventricular fibrillation and cardiac arrest after drinking homemade Aconitum kusnezoffii-infused liquor.

J Med Case RepOct 16, 2026Read case
Clinical ResearchOrthopedic Surgery

Effectiveness of kinesio tape in the treatment of patients with plantar fasciitis: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed kinesio tape (KT) for plantar fasciitis, including 16 randomized controlled trials.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchNephrology

Peritoneal catheter fixation versus nonfixation in open surgery: A meta-analysis.

This meta-analysis compared fixation with nonfixation of peritoneal dialysis (PD) catheters placed by open surgery. Thirteen studies included 648 patients in the fixation group and 627 in the nonfixation group.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchOncology (Medical)

Impact of Phosphatidylinositol 3-Kinase and B-Raf Mutations in Rat Sarcoma Wild-Type Metastatic Colorectal Cancer.

This systematic review and meta-analysis assessed whether PIK3CA and BRAF mutations were associated with outcomes among patients with RAS wild-type metastatic colorectal cancer receiving first-line EGFR inhibitor…

J Vis ExpOct 16, 2026Read summary
Case ReportOtolaryngology (ENT)

Ectopic thyroid tissue accompanied by distinct blood supply and lymphoid tissue within the carotid sheath - a case report.

A 42-year-old man had an asymptomatic right-sided neck mass detected during a routine examination. Ultrasound showed a normally located thyroid and a well-defined 1.3 cm × 0.9 cm × 0.5 cm mass with echotexture similar…

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

Safety and efficacy of a novel miniaturized robotic assisted surgery system in hysterectomy: a prospective, investigational device exemption clinical trial.

This prospective, multicentre, non-randomised Investigational Device Exemption trial assessed the safety and effectiveness of the MIRA miniaturized robotic system for benign hysterectomy.

J Robot SurgOct 16, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Effectiveness of different autologous platelet concentrates for orthodontic canine retraction following premolar extraction: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed platelet-rich plasma (PRP), injectable platelet-rich fibrin (i-PRF), and leukocyte-platelet-rich fibrin (L-PRF) for accelerating orthodontic canine retraction after…

Prog OrthodOct 16, 2026Read summary
Case ReportObstetrics & Gynecology

Psychological factors impeding the progress of labor: case observations and the need for a multidisciplinary approach.

This report describes four labor cases with impaired or arrested progression and psychological factors, without identifiable obstetric pathology.

J Psychosom Obstet GynaecolOct 16, 2026Read case
Case ReportOrthopedic Surgery

Arthroscopic Matrix Augmentation of Partial-Thickness Rotator Cuff Tear Repairs Using a Full-Thickness Human Perinatal Tissue Allograft.

Two patients with persistently symptomatic partial-thickness rotator cuff tears underwent arthroscopic perinatal tissue membrane allograft matrix augmentation using an onlay technique after conservative care failed.

J Vis ExpOct 16, 2026Read case
Case ReportPsychiatry

Clinical Improvement Following Multimodal Treatment in Depersonalization-Derealization Disorder: A Case Report.

A patient with depersonalization-derealization disorder presented with derealization, emotional blunting, poor memory, slowed reactions, and impaired attention.

J Vis ExpOct 16, 2026Read case
Case ReportCardiothoracic Surgery

Large Carinal Chondrosarcoma: Resection of the Main Carina, Distal Trachea, and Orifices of the Mainstem Bronchi and Construction of a New Carina.

A 23-year-old man presented with dyspnea, fatigue, and cough. CT showed a lobulated mass anterior to the distal trachea and main carina; bronchoscopy demonstrated carinal widening, significant stenosis of both mainstem…

Am J Case RepOct 16, 2026Read case
Case ReportNeurology

Spontaneous gene mutation encounters a paternal genetic variant: Nemaline myopathy: a case report and literature review.

A 21-year-old man had progressive weakness beginning in the distal lower limbs at age 3, later affecting proximal and masticatory muscles.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportPediatrics

Cardiac arrest in an adolescent following an overdose of antidepressants comprising sertraline, quetiapine fumarate, and lamotrigine: Case report.

An 11-year-old with depression ingested large quantities of sertraline (3 g), quetiapine fumarate (5 g), and lamotrigine (3 g).

Int J Clin Pharmacol TherOct 16, 2026Read case
Case ReportOncology (Medical)

Case Report WIN-MTB-2024001 - WIN International Molecular Tumor Board: A 55-year-old male with glioblastoma exhibiting amplifications in MDM2 and EGFR.

A 55-year-old man with high-grade glioblastoma had next-generation sequencing findings that included MDM2 and EGFR amplifications and a CDKN2A frameshift mutation.

OncotargetOct 16, 2026Read case
Case ReportHematology

Variability in belumosudil exposure due to coadministration of voriconazole and isavuconazole in a patient with chronic graft-versus-host disease: Case report.

A man in his 50s with steroid-refractory pulmonary chronic graft-versus-host disease after cord blood transplantation received belumosudil, increased from 200 mg once daily to 200 mg twice daily.

Int J Clin Pharmacol TherOct 16, 2026Read case
Case ReportNephrology

Crystalline κ light-chain proximal tubulopathy and Auer rod-like inclusions presenting as Fanconi syndrome: A case report.

A 53-year-old man presented with Fanconi syndrome, with hypokalemia, hypophosphatemia, mild metabolic acidosis, and renal glucosuria.

Clin NephrolOct 16, 2026Read case
Clinical ResearchCardiology

Dapagliflozin After Transcatheter Aortic Valve Implantation According to Frailty in DapaTAVI Trial.

This post hoc analysis of the multicenter randomized DapaTAVI trial examined whether frailty modified dapagliflozin’s effects after transcatheter aortic valve implantation.

J Am Heart AssocOct 16, 2026Read summary

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