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2000 articles

October 202624

Clinical ResearchPsychiatry

Attachment styles and problematic involvement in potentially addictive behaviours: A systematic review and meta-analysis.

This systematic review and meta-analysis examined associations between attachment styles and problematic involvement in behaviours described as addictions, using peer-reviewed studies published before July 23rd, 2026.

Clin Psychol RevOct 2, 2026Read summary
Clinical ResearchNeurology

40 Hz transcutaneous auricular vagus nerve stimulation enhances verbal free recall in healthy adults by modulating frontal theta oscillations.

This randomized, single-blind, sham-controlled, three-arm trial examined whether 20 Hz or 40 Hz transcutaneous auricular vagus nerve stimulation (taVNS) affected verbal free recall and resting-state EEG theta activity…

NeuroimageOct 2, 2026Read summary
Clinical ResearchInfectious Diseases

Participant experiences of stopping ART as part of a clinical trial; findings from a qualitative study within the RIO trial in the United Kingdom.

This qualitative study explored the experiences of 20 cisgender men living with HIV who participated in the phase 2 RIO trial, which involved analytical treatment interruptions (ATIs).

HIV Res Clin PractOct 2, 2026Read summary
Clinical ResearchOrthopedic Surgery

Outcome assessment in frozen shoulder trials: A systematic review and COSMIN-informed recommendations.

This systematic review mapped outcome measures in 927 randomized controlled trials (RCTs) of frozen shoulder and conducted a COSMIN-informed appraisal of measurement-property evidence for commonly used instruments.

Complement Ther MedOct 2, 2026Read summary
Case ReportPediatrics

Spinal Muscular Atrophy.

This article reviews the history, epidemiology, genetics, clinical presentation, multidisciplinary management, and established and emerging therapies for patients with spinal muscular atrophy.

Continuum (Minneap Minn)Oct 2, 2026Read case
Case ReportGastroenterology

Endoscopic double-layer nylon rope ligation for rescue of gastric ulcer bleeding after failed OTSC treatment: A case report (with video).

A 61-year-old man presented with hematemesis and melena due to a bleeding gastric ulcer classified as Forrest IIa. After initial treatment with an over-the-scope clip (OTSC) failed, he underwent endoscopic double-layer…

Medicine (Baltimore)Oct 2, 2026Read case
Case ReportGastroenterologyOpen access

Markedly Elevated CA 19-9 in Type I Mirizzi Syndrome in the Absence of Malignancy: A Case Report.

A 50-year-old man presented with acute obstructive jaundice, fever, and right upper quadrant pain; serum CA 19-9 was 1000 U/mL.

Int Med Case Rep JOct 2, 2026Read case
Case ReportUrologyOpen access

Isolated Prostatic Tuberculosis Coexisting with Benign Prostatic Hyperplasia: A Case Report.

A 70-year-old man presented with one month of lower urinary tract symptoms and recurrent urinary retention requiring repeated catheterization.

Int Med Case Rep JOct 2, 2026Read case
Clinical ResearchNeurosurgeryOpen access

Non-Ischemic Cerebral Enhancing (NICE) lesions after flow diversion for intracranial aneurysms: a systematic review with case-level synthesis.

This PROSPERO-registered systematic review synthesized reports of delayed non-ischemic cerebral enhancing (NICE) lesions after flow-diverter treatment of intracranial aneurysms; heterogeneity precluded meta-analysis.

BMC NeurolOct 2, 2026Read summary
Case ReportAnesthesiologyOpen access

Comparisons in Analgesic Effects Between Ultrasound-Guided Erector Spinae Plane Block and Ultrasound-Guided Modified Intercostal Nerve Block in Modified Radical Mastectomy: A Randomized Controlled Trial.

Postoperative acute pain is a common challenge after breast cancer surgery. This randomized controlled trial compared the analgesic effects of ultrasound-guided erector spinae plane block (ESPB) and modified intercostal…

Drug Des Devel TherOct 2, 2026Read case
Clinical ResearchEndocrinologyOpen access

Effects of SGLT-2 Inhibitors on Plasma Concentrations and Renal Clearance of the Risk Marker Trimethylamine-N-Oxide in Patients With Type-2 Diabetes.

This randomized controlled trial investigated the effects of SGLT-2 inhibitors empagliflozin and dapagliflozin on plasma levels and renal clearance of trimethylamine-N-oxide (TMAO) in patients with Type 2 diabetes.

Endocrinol Diabetes MetabOct 2, 2026Read summary
Clinical ResearchHematology

Regional practice differences significantly affect the benefit of post-HCT gilteritinib in FLT3-ITD AML.

The phase 3 MORPHO trial evaluated the efficacy of gilteritinib versus placebo in post-hematopoietic cell transplantation (HCT) for FLT3-ITD AML patients.

Blood AdvOct 2, 2026Read summary
Clinical ResearchNephrology

Facilitators of Peer Support Among Patients With Chronic Kidney Disease: A Systematic Review and Qualitative Meta-Synthesis.

This systematic review and qualitative meta-synthesis examined facilitators of peer support among patients with chronic kidney disease (CKD).

J Ren CareOct 2, 2026Read summary
Clinical ResearchCardiologyOpen access

Efficacy and Safety of Oral Non-Statin Lipid-Lowering Therapies in Dyslipidaemia: A Systematic Review and Network Meta-Analysis.

This systematic review and network meta-analysis evaluated the efficacy and safety of oral non-statin lipid-lowering therapies in adults with dyslipidaemia.

Endocrinol Diabetes MetabOct 2, 2026Read summary
Clinical ResearchOncology (Medical)

MRD negativity by PBMCs and ctDNA confirms deep and durable responses after epcoritamab monotherapy in R/R FL.

The EPCORE NHL-1 trial evaluated the efficacy of epcoritamab, a CD3 × CD20 bispecific antibody, in patients with relapsed/refractory follicular lymphoma (FL) after at least two prior therapies.

Blood AdvOct 2, 2026Read summary
Clinical ResearchEndocrinology

Native collagen matrix plus PHMB antimicrobial in hard-to-heal diabetic foot ulcers: results from the PREPARE randomised controlled trial.

The PREPARE prospective, multicentre randomised controlled trial compared purified native type 1 collagen extracellular matrix plus polyhexamethylene biguanide (PCMP) with standard care (SoC) alone in patients with…

J Wound CareOct 2, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Intraoperative Dexmedetomidine and Postoperative Delirium After Head and Neck Cancer Surgery with Free-Flap Reconstruction: A Secondary Analysis of a Randomized Placebo-Controlled Trial.

This delirium-focused secondary analysis of a single-centre, randomized, double-blind, placebo-controlled trial examined adults undergoing elective head and neck cancer surgery with free-flap reconstruction.

Drug Des Devel TherOct 2, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Clinical outcomes of early versus standard liver transplantation in patients with alcohol-related liver disease: a meta-analysis.

This meta-analysis compared early and standard liver transplantation in patients with alcohol-related liver disease. It included 12 studies and 2323 patients.

Langenbecks Arch SurgOct 2, 2026Read summary
Clinical ResearchAllergy & ImmunologyOpen access

Treatment of Multifood Allergy With Omalizumab or Multiallergen Oral Immunotherapy: A Randomized Clinical Trial.

This randomized clinical trial compared the efficacy of omalizumab versus multiallergen oral immunotherapy (MOIT) in treating multifood allergies in participants aged 1 to 55 years.

JAMA PediatrOct 1, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Platelet-rich plasma versus corticosteroid injections for facet and sacroiliac joint pain: a systematic review and meta-analysis with trial sequential analysis.

This systematic review and meta-analysis evaluated the efficacy of platelet-rich plasma (PRP) versus corticosteroid injections for treating facet and sacroiliac joint pain in 392 patients.

Pain MedOct 1, 2026Read summary
Clinical ResearchPediatricsOpen access

Family-Centered Child Obesity Treatment: The TEAM UP Randomized Clinical Trial.

This pragmatic randomized clinical trial evaluated the effectiveness of enhanced standard of care with family-based behavioral treatment (ESOC+FBT) compared to enhanced standard of care alone (ESOC) in reducing percent…

JAMA PediatrOct 1, 2026Read summary
Clinical ResearchPediatricsOpen access

Erythropoietin for Neonatal Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.

This multicenter randomized clinical trial evaluated the efficacy of erythropoietin (EPO) as an adjunct to therapeutic hypothermia in infants with moderate to severe hypoxic-ischemic encephalopathy (HIE).

JAMA PediatrOct 1, 2026Read summary
Clinical ResearchObstetrics & Gynecology

A double-blind multi-centre randomised placebo-controlled trial of doxycycline in women with recurrent miscarriage and chronic endometritis defined by CD138 positive stromal cells.

This multicenter, double-blind, randomized controlled trial evaluated the effect of preconceptual doxycycline on live birth rates in women with recurrent miscarriage and chronic endometritis defined by CD138 positive…

Hum ReprodOct 1, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Health Communication and Stepped Reminders Interventions for Lung Cancer Screening: A Randomized Clinical Trial.

This randomized clinical trial evaluated two patient-centered interventions aimed at increasing adherence to annual lung cancer screening among patients with normal findings.

JAMA Intern MedOct 1, 2026Read summary

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