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2000 articles

October 202624

Clinical ResearchPediatrics

Air versus supplemental oxygen for resuscitation of term or late preterm infants at birth.

This Cochrane systematic review and meta-analysis assessed randomised and quasi-randomised trials comparing air with supplemental oxygen for resuscitation at birth in term and late preterm infants needing respiratory…

Cochrane Database Syst RevOct 27, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Closed percutaneous reduction versus mini-open sinus tarsi approach for fixation of displaced intra-articular calcaneal fractures: a systematic review and meta-analysis.

This systematic review and meta-analysis compared closed percutaneous reduction (PR) with the mini-open sinus tarsi approach (STA) for acute displaced intra-articular calcaneal fractures.

Eur J Orthop Surg TraumatolOct 27, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Rare and Novel Hepatitis C Virus Genotype Subtypes and Response to Sofosbuvir/Velpatasvir in A5360 (MINMON) Clinical Trial.

This analysis of samples from the multicountry ACTG A5360 (MINMON) clinical trial characterized rare and novel hepatitis C virus (HCV) subtypes and assessed baseline resistance-associated substitutions and response to…

J Viral HepatOct 27, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

E-Cigarettes with and without Behavioral Support for Smoking Cessation.

This randomized controlled trial compared an e-cigarette starter pack alone, the starter pack plus multisession telephone-based behavioral support, and automated supportive messages among people who smoked and were…

NEJM EvidOct 27, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Cost-effectiveness of recommended interventions for managing low back pain: A systematic review.

This systematic review assessed the cost-effectiveness of guideline-recommended interventions for non-specific low back pain compared with usual care.

PLoS MedOct 27, 2026Read summary
Clinical ResearchOrthopedic Surgery

Comparative effectiveness of three splints for rehabilitation after finger flexor tendon repair (FIRST): randomised controlled trial.

The FIRST pragmatic, multicentre randomised trial compared forearm-based long, Manchester short, and relative motion flexion mini splints for rehabilitation after primary zone 1 or 2 finger flexor tendon repair.

BMJOct 27, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Effectiveness of theory-based educational interventions on fertility and childbearing intentions: a systematic review and meta-analysis among Iranian populations.

This systematic review and meta-analysis assessed theory-based educational interventions and fertility or childbearing intentions among Iranian populations.

Hum Fertil (Camb)Oct 27, 2026Read summary
Clinical ResearchPediatrics

Endobronchial Valves for Persistent Air Leak and Bronchopleural Fistula in Children: A Systematic Review of Indications, Procedural Approaches, and Outcomes.

This systematic review examined bronchoscopic endobronchial or intrabronchial valve placement for persistent air leak, bronchopleural fistula, or pneumothorax with ongoing air leak in children and late adolescents.

J Bronchology Interv PulmonolOct 27, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Virtual reality surgical simulator training of residents and early-career surgeons for pedicle screw placement: a systematic review and meta-analysis.

This systematic review and meta-analysis included six randomized controlled trials comparing virtual reality (VR) simulation with conventional teaching for pedicle screw placement training in residents and early-career…

Eur J Orthop Surg TraumatolOct 27, 2026Read summary
Case ReportDermatology

Long-term remission of severe psoriasis following CD19-directed chimeric antigen receptor T-cell therapy for follicular lymphoma.

A 60-year-old woman with a 49-year history of severe plaque psoriasis received autologous CD19-directed CAR-T therapy for follicular lymphoma.

Clin Exp DermatolOct 27, 2026Read case
Clinical ResearchPsychiatry

Combining Cognitive Training and Brain Stimulation: A Novel Approach to Address Disordered Eating and Antipsychotic-Induced Weight Gain in People With Severe Mental Illness.

This double-blind, parallel-group, sham-controlled randomised trial assessed the feasibility of combining Approach Bias Modification Training (ABMT) with real or sham transcranial direct current stimulation (tDCS) in…

Early Interv PsychiatryOct 27, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Safety and efficacy of dual immune checkpoint inhibition for melanoma brain metastases and its comparison to ICI monotherapy: A systematic review and meta-analysis.

This PRISMA-based systematic review and meta-analysis pooled prospective and retrospective studies of adults with cutaneous or mucosal melanoma brain metastases treated with dual immune checkpoint inhibition (ICI), and…

Neurosurg RevOct 27, 2026Read summary
Clinical ResearchPediatricsOpen access

Permissive Blood Pressure Targets in Pediatric Critical Care: The PRESSURE Randomized Clinical Trial.

The multicenter, unblinded pragmatic randomized PRESSURE trial compared a permissive mean arterial pressure (MAP) target (greater than the fifth percentile for age) with usual physician-set targets in hypotensive…

JAMAOct 27, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Effects of Whey Protein Supplementation on Muscle Damage, Hepatic Stress, and Inflammatory Markers in Power- and Endurance-Trained Athletes.

This randomized, double-blind, placebo-controlled trial examined 8 weeks of whey protein supplementation (30 g/day) in 59 male power- and endurance-trained athletes.

Eur J Sport SciOct 27, 2026Read summary
Case ReportGastroenterologyOpen access

Protein-losing enteropathy as a rare presentation of small bowel T-cell post-transplant lymphoproliferative disease.

A kidney transplant recipient developed episodic diarrhea, with initial investigations showing no bowel pathology. She later developed fluid retention associated with hypoalbuminemia, and technetium-99m human serum…

CEN Case RepOct 27, 2026Read case
Clinical ResearchNeurology

Measuring the impact of migraine: a systematic review of the measurement properties of MIDAS, HIT-6, and MSQoL.

This systematic review compared the measurement properties of MIDAS, HIT-6, and MSQoL for assessing migraine impact. Following COSMIN methods, it included 22 studies with 20,455 participants.

Arq NeuropsiquiatrOct 27, 2026Read summary
Case ReportInternal Medicine (General)

A 58-Year-Old Woman with Abdominal Pain, Fever, and Cough.

A 58-year-old woman presented with fever, abdominal pain, and a nonproductive cough. The report describes a diagnostic evaluation using focused history, physical examination, and testing, with the differential diagnosis…

NEJM EvidOct 27, 2026Read case
Case ReportInfectious Diseases

Isolated Disturbance of Consciousness as Initial Presentation of Staphylococcus aureus Endocarditis: A Case Report With Brief Literature Review.

A man in his 50s presented with isolated disturbance of consciousness and no reported fever, although his admission temperature was 38°C.

Am J Case RepOct 27, 2026Read case
Clinical ResearchInfectious Diseases

Assessing stigma and perceptions of respectful care in Malawi's index case testing program: Findings from a cluster randomized controlled trial.

This cluster randomized controlled trial assessed whether enhanced stigma-reduction training improved healthcare worker (HCW) attitudes and client experiences in Malawi’s HIV index case testing program.

PLoS OneOct 27, 2026Read summary
Clinical ResearchGeneral Surgery

STRONG prehabilitation before elective ventral hernia repair: Learnings from recruitment challenges in a randomized controlled trial.

The multicentre, parallel-group STRONG-Hernia randomised controlled trial assessed intensive lifestyle prehabilitation before elective ventral hernia repair in adults with at least one risky smoking, nutrition, alcohol…

PLoS OneOct 27, 2026Read summary
Clinical ResearchCardiology

Effectiveness of Wrist-Worn Wearable-Guided Cardiac Rehabilitation Delivered Through Fully Remote or Hybrid Programs in Patients With Cardiovascular Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis assessed randomized trials of wrist-worn wearable-guided cardiac rehabilitation delivered remotely or in hybrid formats during phase II or III rehabilitation for adults with…

JMIR Mhealth UhealthOct 27, 2026Read summary
Clinical ResearchVascular SurgeryOpen access

Revascularization in Asymptomatic Carotid Artery Stenosis With Hemodynamic Impairment and Cognitive Outcomes: The CREST-H Substudy of the CREST-2 Randomized Clinical Trial.

This multicenter substudy of a phase 3 randomized clinical trial examined whether baseline cerebral hemodynamic impairment modified cognitive outcomes after carotid revascularization in adults with high-grade…

JAMAOct 27, 2026Read summary
Clinical ResearchDermatology

The follicular microbiome in hair-follicle-associated inflammatory diseases: a systematic review.

This systematic review qualitatively synthesized culture-independent studies of the bacterial hair-follicle microbiome in inflammatory hair-follicle-associated diseases.

Clin Exp DermatolOct 27, 2026Read summary
Case ReportUrologyOpen access

A rare twist after Ex-vivo RIRS: graft parenchymal urine leak in a living donor kidney.

A 29-year-old man received a living-donor kidney after ex-vivo retrograde intrarenal surgery (RIRS) to remove a 5 mm upper-pole calculus.

CEN Case RepOct 26, 2026Read case

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