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2000 articles
October 202624
Psychological Interventions Targeting Auditory Hallucinations in Persons With Psychotic Disorders: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis assessed randomised trials of psychological and psychosocial interventions targeting auditory hallucinations in adults with schizophrenia spectrum disorders.
Modified tibiofibular synostosis vs. Burgess stump in a bilateral amputee: a case report.
A bilateral transtibial amputee had a modified tibiofibular synostosis (TFS) stump on the right and a conventional Burgess-type stump (BTS) on the left.
Anterior Stromal Melt Following Implantation of a Large Size Corneal Allogenic Intrastromal Ring Segment (CAIRS).
To report delayed anterior stromal melt following corneal allogenic intrastromal ring segment (CAIRS) implantation in a patient without known systemic or ocular risk factors.
First-line biologic and targeted synthetic DMARDs versus methotrexate in early rheumatoid arthritis: a meta-analysis of remission outcomes.
This systematic review and meta-analysis of randomized trials compared initial biologic and targeted synthetic DMARDs (b/tsDMARDs), alone or with methotrexate, against methotrexate in methotrexate-naïve adults with…
Longitudinal clinical outcomes after amyloid clearance in aducanumab phase 3 studies.
This exploratory analysis pooled participants from the randomized phase 3 ENGAGE and EMERGE aducanumab trials who entered a long-term extension or later redosing study.
Retrospective RNA Sequencing Reclassifies a Historical t(5;12) Eosinophilic Neoplasm From Presumed PDGFRB Rearrangement to ETV6::ACSL6.
A woman with a chronic eosinophilic myeloid neoplasm had a t(5;12) that raised suspicion of PDGFRB involvement, but contemporary testing did not identify a rearrangement and empiric imatinib produced no meaningful…
Effect of a Computer-Aided Device on Endoscopists' Biopsy Practice for Gastric Neoplasms: A Secondary Analysis of a Randomized Controlled Trial.
This secondary analysis of a randomized controlled trial compared AI-assisted with standard gastric screening, examining biopsy practice for documented lesions.
Digital health interventions for psychological and cognitive care in cancer patients and caregivers: A RE-AIM-based systematic review.
This PRISMA-guided systematic review assessed the internal and external validity of digital interventions for psychological and cognitive concerns among people with cancer, caregivers, and family members, using the…
Prevalence and Predictors of Depressive Symptom Trajectories in Older Adults: A Systematic Review.
This systematic review examined longitudinal patterns of depressive symptoms and their predictors among adults aged 60 years or older.
Resolution of restless legs syndrome after postdilution online hemodiafiltration using a vitamin E-bonded polysulfone membrane: a report of two cases.
Two patients with long-standing, refractory restless legs syndrome underwent high-efficiency online hemodiafiltration but did not achieve sufficient symptom relief.
The role of vitamin D signalling in β cell apoptosis: a systematic review.
This systematic review examined the role of vitamin D signalling in pancreatic β-cell apoptosis, analyzing 26 studies across various models.
Phase 1 dose escalation and expansion trial of the bispecific CD47 inhibitor and CD40 agonist Fc-fusion protein SL-172154 (SIRPα-Fc-CD40L) in patients with higher-risk myelodysplastic syndrome or acute myeloid leukemia.
This Phase I clinical trial evaluated the safety and efficacy of the bispecific CD47 inhibitor SL-172154 combined with azacitidine (AZA) in patients with higher-risk myelodysplastic syndrome (HR-MDS) or acute myeloid…
Dose Considerations and Generalization Following Script Training for Poststroke Aphasia: A Randomized Factorial Clinical Trial.
This single-site, single-blind, 2 × 2 factorial randomized controlled trial examined how script length and session frequency affect treatment outcomes in 85 people with chronic poststroke aphasia.
Variants in CEP135 Cause Congenital Microcephaly and Primary Ciliary Dyskinesia.
Three children from two families presented with congenital microcephaly and chronic respiratory issues consistent with primary ciliary dyskinesia (PCD). Diagnostic testing revealed autosomal recessive variants in CEP135.
Calcitonin-negative 'MTC-like' thyroid paraganglioma revealing an SDHD-related hereditary paraganglioma syndrome: functional confirmation of a non-canonical splice-site variant.
A 36-year-old woman presented with a 20-mm thyroid nodule classified as EU-TIRADS 4 and Bethesda III, with normal serum calcitonin levels.
Psychoeducation for Youth at Clinical High-Risk of Psychosis.
This clinical trial evaluated the effects of psychoeducation on 54 youth at clinical high risk of psychosis. After 2-6 months, significant improvements were noted in attenuated psychotic symptoms, depression, and…
TMS-Derived Neurophysiological Measures of Corticospinal Excitability, Intracortical Excitability, and Interhemispheric Interactions Associated With Post-Stroke Motor Recovery: A Systematic Review.
This systematic review evaluated the relationship between TMS-derived neurophysiological measures and motor recovery in adults post-stroke, synthesizing data from 16 randomized controlled trials.
Updated Meta-Analysis of Left Atrial Appendage Closure Versus Oral Anticoagulation to Prevent Stroke in Atrial Fibrillation.
This systematic review and meta-analysis pooled six randomized controlled trials comparing percutaneous left atrial appendage closure (LAAC) with oral anticoagulation in 7028 patients with nonvalvular atrial…
Chlamydia psittaci Meningitis, Chile, 2023.
A 50-year-old farm worker in Chile presented with meningitis, which was confirmed to be caused by Chlamydia psittaci through cerebrospinal fluid quantitative real-time PCR and serology.
Health Economic & Implementation Determinants of Prehospital Stroke Triage Tools: A Systematic Review.
This systematic review evaluated health economic outcomes and implementation determinants of prehospital triage tools for suspected ischaemic stroke patients.
Sensory processing and executive functioning interaction in neurodevelopmental disorders and at-risk conditions: A systematic review and meta-analysis.
This systematic review and meta-analysis examined associations between sensory processing (SP) and executive functioning (EF) in children and adolescents aged 0–18 with neurodevelopmental disorders or at-risk…
Presentation and management of tislelizumab induced toxic optic neuropathy.
A woman with metastatic lung adenocarcinoma developed painless, progressive bilateral visual blurring after receiving second-line treatment with gemcitabine, carboplatin, and tislelizumab.
Who is getting better in treatment? Dynamics in risk processes as a signature of short-term suicide treatment response.
This analysis of adults receiving up to 12 sessions of suicide-focused therapy within a randomized clinical trial examined whether weekly patterns in suicide risk and resilience differed according to suicide attempts…
National and Subnational Trends in Ischemic Heart Disease Burden in Iran, 1990-2023: A Systematic Review.
This systematic review synthesized national and subnational evidence on ischemic heart disease (IHD) in Iran from 1990 to 2023, including model-based estimates and empirical studies.
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