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2000 articles
October 202624
Chatbot Intervention and Cancer Risk Knowledge in Adolescents and Young Adults With Cancer Predisposition: A Randomized Clinical Trial.
This multicentre randomized clinical trial evaluated whether a tailored electronic chatbot improved cancer-risk understanding among English-speaking adolescents and young adults aged 12 to 24 years with one of nine…
Back-Table Reduction of a Deceased Adult Donor Kidney for Transplantation Into a Small Child: A Six-Year Follow Up.
A 15-month-old boy with congenital nephrotic syndrome received a left kidney from a 46-year-old deceased donor. Due to size mismatch, the upper pole of the kidney was resected ex vivo, reducing its volume by one-third.
Meningococcal meningitis in patients under prolonged eculizumab therapy: Clinical and immunological observations from a case series.
Two patients undergoing prolonged eculizumab therapy developed meningococcal meningitis despite prior vaccination. The clinical presentation included typical symptoms of meningitis, and diagnostic workups confirmed the…
How I do it: meningioangiomatosis of the sylvian fissure. The need for a tailored functional neurosurgery.
A patient with drug-resistant epileptic seizures presented with meningioangiomatosis located in the right sylvian fissure, affecting the M1-M2 segments of the right middle cerebral artery.
Positive emotions and credibility: Understanding how a community-engaged online campaign featuring clinician testimonials improved rural vaccine promotion.
This four-arm randomized survey experiment tested the community-engaged Communities Confronting COVID-19 campaign among 1,364 rural U.S. residents.
The Acceptability and Experiences of Participating in a Preoperative Intentional Weight-Loss Programme From Diagnosis to Surgery for Colorectal Cancer.
This qualitative study, embedded in the CARE randomised controlled trial, explored how patients with colorectal cancer experienced an intensive, dietitian-supported weight-loss programme between diagnosis and surgery.
Pediatric Spinal Cord Astrocytoma With Granular Cell-Like Morphology and KIAA1549::BRAF Fusion.
A pediatric patient presented with a spinal cord tumor exhibiting prominent granular cell-like features, complicating the initial diagnosis.
Irritability in the Mix: An Exploratory Study of the Role of Irritability in Characterising Mood Disorders.
This randomized controlled trial explored the relationship between irritability and mixed states in 82 patients with bipolar disorder over 18 months.
Efficacy and Safety of Lorundrostat for Uncontrolled and Treatment-resistant Hypertension: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the efficacy and safety of lorundrostat in adults with uncontrolled or treatment-resistant hypertension.
Efficacy and Safety of CETP Inhibitors in Patients With Atherosclerotic Cardiovascular Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the efficacy and safety of cholesteryl ester transfer protein (CETP) inhibitors in 62,565 patients with atherosclerotic cardiovascular disease.
The predictive value of early-pregnancy mean platelet volume for preeclampsia: A meta-analysis.
This meta-analysis assessed whether mean platelet volume (MPV) measured before 20 weeks’ gestation is associated with subsequent preeclampsia.
Prednisone in the Management of Pericarditis: A Systematic Review.
This systematic review evaluated the use of oral corticosteroids, primarily prednisone, in adults with acute or recurrent pericarditis.
Lenalidomide-Related Diarrhea in Patients with Multiple Myeloma Is Associated with Gut Microbiota Dysbiosis and Disruption of the Bile Acid Pool.
This Phase II randomized controlled trial investigated the relationship between gut microbiota dysbiosis, bile acid pool disruption, and lenalidomide-related diarrhea (LRD) in patients with multiple myeloma.
Association of HRD Score With Efficacy of Neoadjuvant Short-Course Radiotherapy Plus Sequential Chemoimmunotherapy in pMMR Locally Advanced Rectal Cancer.
This Phase II clinical trial examined the relationship between homologous recombination deficiency (HRD) score and treatment response in 32 patients with mismatch repair-proficient locally advanced rectal cancer…
Diagnostic Accuracy of Circulating MicroRNAs for Coronary Artery Disease: An Updated Systematic Review and Meta-analysis.
This systematic review and meta-analysis evaluated the diagnostic accuracy of circulating microRNAs (miRNAs) for coronary artery disease (CAD) in 3,879 participants across 24 studies.
Female Soccer Players at High Risk of Injury Maintained Improved Knee Abduction Load 6 Months After Neuromuscular Training Program.
This randomized controlled trial evaluated the effects of a 6-week neuromuscular training (NMT) program on knee abduction moment (KAM) in 150 adolescent female soccer players.
A Composite Ovine Forestomach Matrix and Hyaluronic Acid CAMP for the Treatment of Full Thickness Wounds of the Foot in People With Diabetes: A Randomized Controlled Trial.
This randomized controlled trial evaluated the efficacy of a novel composite CAMP, OFM-HA, in treating full thickness diabetic foot ulcers (DFUs) in 143 patients.
Factors influencing access to green health prescribing in primary care for older adults - a qualitative systematic review.
This systematic review examined barriers and enablers to green health prescribing (GHP) for older adults with long-term conditions.
Evaluating plasma ferritin and suPAR as treatable traits for critically ill patients with COVID-19 treated with anakinra: an exploratory analysis of the immune modulation domain of the REMAP-CAP randomised clinical trial.
This exploratory analysis of the REMAP-CAP randomized clinical trial evaluated plasma ferritin and suPAR as potential treatable traits for anakinra in critically ill COVID-19 patients.
Portable Dynamometry Is Reliable for Measuring Knee and Ankle Strength in Daily Practice: Results From a Systematic Review With Meta-analysis and Evidence Gap Map Using the COSMIN Methodology.
This systematic review and meta-analysis evaluated the reliability and criterion validity of portable dynamometers for measuring knee and ankle muscle strength in both uninjured individuals and those with lower-limb…
Online stepped care for the treatment of posttraumatic stress disorder: A randomized controlled noninferiority trial.
This randomized controlled non-inferiority trial compared online stepped care with telehealth cognitive processing therapy (CPT) in 84 adults with PTSD or subthreshold PTSD.
Opioid-Sparing Analgesia After Laparoscopic Gastrectomy: Exploratory Clinical Outcomes and Cine-MRI Assessment of Small-Bowel Motility.
This randomized controlled trial evaluated opioid-sparing multimodal analgesia versus conventional opioid analgesia in 130 patients undergoing laparoscopic radical gastrectomy.
Use of a Synthetic Polylactic Acid Matrix for Pyoderma Gangrenosum: A Case Series.
This case series involved six patients with chronic, non-healing ulcers due to pyoderma gangrenosum, persisting for 6 months to 3 years.
Effects of Yoga on Rheumatoid Arthritis: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effects of yoga on psychological function and inflammation in individuals with rheumatoid arthritis (RA).
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