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2000 articles

October 202624

Clinical ResearchInfectious Diseases

Next-Generation Bed Nets to Control Malaria in Côte d'Ivoire.

This cluster-randomized clinical trial compared pyrethroid-only long-lasting insecticidal nets with piperonyl butoxide-pyrethroid (PBO-py) and chlorfenapyr-pyrethroid (CFP-py) nets in villages in Côte d'Ivoire.

NEJM EvidOct 27, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Effects of Whey Protein Supplementation on Muscle Damage, Hepatic Stress, and Inflammatory Markers in Power- and Endurance-Trained Athletes.

This randomized, double-blind, placebo-controlled trial examined 8 weeks of whey protein supplementation (30 g/day) in 59 male power- and endurance-trained athletes.

Eur J Sport SciOct 27, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Safety and efficacy of dual immune checkpoint inhibition for melanoma brain metastases and its comparison to ICI monotherapy: A systematic review and meta-analysis.

This PRISMA-based systematic review and meta-analysis pooled prospective and retrospective studies of adults with cutaneous or mucosal melanoma brain metastases treated with dual immune checkpoint inhibition (ICI), and…

Neurosurg RevOct 27, 2026Read summary
Clinical ResearchVascular SurgeryOpen access

Revascularization of Asymptomatic Carotid Artery Stenosis: Cognitive Results of the CREST-2 Randomized Trials.

This prespecified cognitive-outcomes analysis of the multicentre, randomised CREST-2 trials assessed patients aged 35 years or older with at least 70% asymptomatic carotid stenosis.

JAMAOct 27, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Cost-effectiveness of recommended interventions for managing low back pain: A systematic review.

This systematic review assessed the cost-effectiveness of guideline-recommended interventions for non-specific low back pain compared with usual care.

PLoS MedOct 27, 2026Read summary
Case ReportNephrologyOpen access

Ravulizumab monotherapy for anti-CFH antibody-associated aHUS in an elderly patient: a case report highlighting individualized clinical decision-making.

An 85-year-old man presented with acute kidney injury, thrombocytopenia, microangiopathic hemolytic anemia, and severe hypertension.

CEN Case RepOct 27, 2026Read case
Clinical ResearchOncology (Medical)Open access

Body image distress in women and men with advanced pancreatic cancer approaching death - post-hoc analyses from the MISTRAL-trial.

This post-hoc analysis of data from the MISTRAL trial examined changes in body image distress and weight worries among 125 women and men with pancreatic cancer during the six months before death.

Support Care CancerOct 27, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Closed percutaneous reduction versus mini-open sinus tarsi approach for fixation of displaced intra-articular calcaneal fractures: a systematic review and meta-analysis.

This systematic review and meta-analysis compared closed percutaneous reduction (PR) with the mini-open sinus tarsi approach (STA) for acute displaced intra-articular calcaneal fractures.

Eur J Orthop Surg TraumatolOct 27, 2026Read summary
Clinical ResearchPsychiatry

Combining Cognitive Training and Brain Stimulation: A Novel Approach to Address Disordered Eating and Antipsychotic-Induced Weight Gain in People With Severe Mental Illness.

This double-blind, parallel-group, sham-controlled randomised trial assessed the feasibility of combining Approach Bias Modification Training (ABMT) with real or sham transcranial direct current stimulation (tDCS) in…

Early Interv PsychiatryOct 27, 2026Read summary
Case ReportPediatricsOpen access

Reconstructive management of an extensive myelomeningocele defect using allogeneic fascia lata as temporary biological coverage: a case-based mini-review.

A term male newborn had a 16 × 10 cm thoracolumbosacral myelomeningocele with too little surrounding skin for tension-free primary closure.

Childs Nerv SystOct 27, 2026Read case
Clinical ResearchGeneral Surgery

Associating liver partition and portal vein ligation for staged hepatectomy procedure versus conventional two-stage hepatectomy for colorectal liver metastasis.

This Cochrane systematic review and meta-analysis assessed ALPPS versus conventional two-stage hepatectomy in adults with colorectal liver metastases and an estimated future liver remnant below 30% of total liver…

Cochrane Database Syst RevOct 27, 2026Read summary
Clinical ResearchFamily Medicine

An mHealth Stress Management Intervention for Latino Millennial Caregivers: Pilot Feasibility Randomized Controlled Trial.

This pilot feasibility randomized controlled trial evaluated a culturally tailored, automated mobile intervention for stress management and emotional regulation among Latino millennial caregivers in the United States.

JMIR Form ResOct 27, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

E-Cigarettes with and without Behavioral Support for Smoking Cessation.

This randomized controlled trial compared an e-cigarette starter pack alone, the starter pack plus multisession telephone-based behavioral support, and automated supportive messages among people who smoked and were…

NEJM EvidOct 27, 2026Read summary
Clinical ResearchInfectious Diseases

Measles transmission-related epidemiological parameter estimates: a systematic review and meta-analysis.

This systematic review and meta-analysis synthesized English- and French-language primary studies reporting measles transmission-related epidemiological parameters, identified through 14 May 2024.

Epidemiol InfectOct 27, 2026Read summary
Clinical ResearchDermatology

Efficacy and safety of icotrokinra for plaque psoriasis: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed icotrokinra, an oral IL-23 receptor antagonist, in adolescents and adults with moderate-to-severe plaque psoriasis.

Clin Exp DermatolOct 27, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Effectiveness of theory-based educational interventions on fertility and childbearing intentions: a systematic review and meta-analysis among Iranian populations.

This systematic review and meta-analysis assessed theory-based educational interventions and fertility or childbearing intentions among Iranian populations.

Hum Fertil (Camb)Oct 27, 2026Read summary
Clinical ResearchPsychiatryOpen access

Efficacy of Personalizing Cognitive Remediation for Schizophrenia by Targeting Impairments in Early Auditory Processing.

This randomized controlled trial tested whether personalizing cognitive remediation (CR) by baseline early auditory processing (EAP) status improved outcomes in 184 outpatient adults with schizophrenia.

Schizophr BullOct 27, 2026Read summary
Clinical ResearchGeneral Surgery

STRONG prehabilitation before elective ventral hernia repair: Learnings from recruitment challenges in a randomized controlled trial.

The multicentre, parallel-group STRONG-Hernia randomised controlled trial assessed intensive lifestyle prehabilitation before elective ventral hernia repair in adults with at least one risky smoking, nutrition, alcohol…

PLoS OneOct 27, 2026Read summary
Clinical ResearchNeurosurgery

Intra-wound Vancomycin Powder for Surgical Site Infection Prophylaxis in Spinal Surgery: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis examined intra-wound vancomycin powder at closure versus no powder in patients undergoing spinal surgery.

J Vis ExpOct 27, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Virtual reality surgical simulator training of residents and early-career surgeons for pedicle screw placement: a systematic review and meta-analysis.

This systematic review and meta-analysis included six randomized controlled trials comparing virtual reality (VR) simulation with conventional teaching for pedicle screw placement training in residents and early-career…

Eur J Orthop Surg TraumatolOct 27, 2026Read summary
Clinical ResearchPediatrics

Efficacy and safety of Lianhua Qingwen versus oseltamivir in children with influenza: a multicenter, randomized, double-blind, positive parallel-controlled study.

This multicenter, randomized, double-blind, positive-controlled trial compared Lianhua Qingwen (LHQW) with oseltamivir in children aged 3–14 years with influenza.

Pharm BiolOct 27, 2026Read summary
Clinical ResearchPediatricsOpen access

Permissive Blood Pressure Targets in Pediatric Critical Care: The PRESSURE Randomized Clinical Trial.

The multicenter, unblinded pragmatic randomized PRESSURE trial compared a permissive mean arterial pressure (MAP) target (greater than the fifth percentile for age) with usual physician-set targets in hypotensive…

JAMAOct 27, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Intrauterine Mepivacaine Instillation vs Placebo for Pain During IUD Placement: A Randomized Clinical Trial.

This multicentre, double-blind, randomised, placebo-controlled trial tested intrauterine mepivacaine before IUD placement in nulliparous individuals aged 18 to 31 years at 11 Swedish clinics.

JAMAOct 27, 2026Read summary
Case ReportGastroenterologyOpen access

Protein-losing enteropathy as a rare presentation of small bowel T-cell post-transplant lymphoproliferative disease.

A kidney transplant recipient developed episodic diarrhea, with initial investigations showing no bowel pathology. She later developed fluid retention associated with hypoalbuminemia, and technetium-99m human serum…

CEN Case RepOct 27, 2026Read case

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