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2000 articles
October 202624
Three-week ileostomy closure after colorectal surgery: a multicenter randomized trial of technical and postoperative outcomes.
This prospective multicenter randomized trial compared ileostomy closure at 3 weeks with conventional delayed closure in 224 patients after restorative colorectal resection.
Assessing stigma and perceptions of respectful care in Malawi's index case testing program: Findings from a cluster randomized controlled trial.
This cluster randomized controlled trial assessed whether enhanced stigma-reduction training improved healthcare worker (HCW) attitudes and client experiences in Malawi’s HIV index case testing program.
Four weeks of isometric handgrip training results in lower awake ambulatory blood pressure compared with control: a randomized clinical trial.
This randomized controlled trial compared handgrip and knee-extension isometric training with control in 67 adults with controlled hypertension receiving antihypertensive medication.
Intrauterine Mepivacaine Instillation vs Placebo for Pain During IUD Placement: A Randomized Clinical Trial.
This multicentre, double-blind, randomised, placebo-controlled trial tested intrauterine mepivacaine before IUD placement in nulliparous individuals aged 18 to 31 years at 11 Swedish clinics.
Isolated Disturbance of Consciousness as Initial Presentation of Staphylococcus aureus Endocarditis: A Case Report With Brief Literature Review.
A man in his 50s presented with isolated disturbance of consciousness and no reported fever, although his admission temperature was 38°C.
Long-term remission of severe psoriasis following CD19-directed chimeric antigen receptor T-cell therapy for follicular lymphoma.
A 60-year-old woman with a 49-year history of severe plaque psoriasis received autologous CD19-directed CAR-T therapy for follicular lymphoma.
The follicular microbiome in hair-follicle-associated inflammatory diseases: a systematic review.
This systematic review qualitatively synthesized culture-independent studies of the bacterial hair-follicle microbiome in inflammatory hair-follicle-associated diseases.
Haemodynamic and Respiratory Effects of Dexmedetomidine as an Adjuvant to Oxycodone Patient-Controlled Analgesia After Lumbar Spinal Fusion: A Post Hoc Analysis of the DoseRespDex Randomised Controlled Trial.
This post hoc analysis of a randomised, double-blind, placebo-controlled trial examined haemodynamic and respiratory effects of dexmedetomidine added to oxycodone patient-controlled analgesia in 98 adults undergoing…
Revascularization in Asymptomatic Carotid Artery Stenosis With Hemodynamic Impairment and Cognitive Outcomes: The CREST-H Substudy of the CREST-2 Randomized Clinical Trial.
This multicenter substudy of a phase 3 randomized clinical trial examined whether baseline cerebral hemodynamic impairment modified cognitive outcomes after carotid revascularization in adults with high-grade…
Safety and efficacy of dual immune checkpoint inhibition for melanoma brain metastases and its comparison to ICI monotherapy: A systematic review and meta-analysis.
This PRISMA-based systematic review and meta-analysis pooled prospective and retrospective studies of adults with cutaneous or mucosal melanoma brain metastases treated with dual immune checkpoint inhibition (ICI), and…
Exposure to antidepressant and antipsychotic medicines in pregnant women and risk of gestational diabetes: a systematic review and meta-analysis of observational studies.
This systematic review and meta-analysis pooled observational studies of gestational diabetes mellitus (GDM) among pregnant women exposed to antidepressants or antipsychotics.
Family Resilience and Coping in Disasters, Pandemics, and Large-Scale Crises: A Systematic Review.
This systematic review synthesized peer-reviewed research on family resilience and coping during disasters, pandemics, and sustained adversity.
Are intervention effects on fruit and vegetable intake maintained after 48 months of follow-up? A randomised controlled community trial.
This randomised controlled community trial assessed whether increases in fruit and vegetable (FV) intake after a 7-month transtheoretical model-based intervention were maintained among users of a Brazilian primary…
Evaluating gain and loss-framed mobile messaging to improve maternal health service uptake: A cluster randomized controlled trial in Jimma, Ethiopia.
This three-arm cluster-randomized controlled trial assessed whether gain- or loss-framed SMS messaging improved maternal health service use among 588 pregnant women in Jimma Zone, Ethiopia.
Association of Screen Time With Physical and Mental Health in University Students: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined screen-time duration and physical and mental health outcomes in university students aged 17 years or older.
Non-recurrent laryngeal nerve with dual branch pattern and merging: a rare anatomical variant encountered during right hemithyroidectomy.
A woman in her 50s underwent right hemithyroidectomy for a benign compressive multinodular goitre. The recurrent laryngeal nerve was not found in its expected tracheo-oesophageal groove position.
Interleukin-6 and C-reactive protein prognostic value following acute coronary syndrome.
This post hoc prognostic analysis of the multicentre ODYSSEY OUTCOMES randomised trial examined hsCRP and IL-6 in 11,817 patients with recent acute coronary syndrome.
Fertility Treatment and Risk of Melanoma: A Certainty-Rated Systematic Review and Meta-Analysis of 3,733,499 Women.
This certainty-rated systematic review and random-effects meta-analysis examined observational evidence on fertility treatment and incident melanoma in women.
Bilateral Xanthogranulomatous Pyelonephritis in a Patient With Spina Bifida and Neurogenic Bladder: A Case Report.
A 30-year-old man with spina bifida and neurogenic bladder managed by intermittent catheterization presented with respiratory distress, profound anemia, and declining function.
Oxalate Nephropathy in a patient with Neuroendocrine tumor receiving Long-acting Octreotide.
A 55-year-old man with metastatic somatostatin receptor-positive neuroendocrine tumour received long-acting octreotide and, later, four cycles of 177 Lu-DOTA-TATE peptide receptor radionuclide therapy (PRRT).
Individual Effects of Angiotensin II Receptor Blockers on Major Adverse Cardiovascular Events: A Systematic Review and Network Meta-Analysis.
This systematic review and random-effects network meta-analysis compared angiotensin II receptor blockers (ARBs) for cardiovascular outcomes in randomized trials not primarily designed to study heart failure.
From Bench to Bedside: Evaluating the Accuracy of Clinical Sensory Testing in Detecting Somatosensory Disorders. A Systematic Review.
This systematic review assessed the diagnostic accuracy of clinical sensory tests (CSTs) for somatosensory disorders across populations and conditions, comparing test results with reference standards.
"What a beautiful gift, life": Dignity therapy and the making of a legacy in a patient with grade 4 glioblastoma.
A man in his mid-40s with grade 4 glioblastoma of the corpus callosum received psycho-oncological support from diagnosis, with parallel support for his caregiver.
Previously Unrecognized Distinct Laryngeal Lesions During Lazertinib Therapy in EGFR-Mutated NSCLC: A Case Series.
Four patients with non-small cell lung cancer developed new voice changes or a globus sensation while receiving lazertinib-based therapy.
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