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2000 articles
October 202624
Phase 3 Antifibrotic-Directed Therapy Outcomes in Idiopathic Pulmonary Fibrosis: Beyond FVC Decline.
This systematic review compared phase 3 randomized, placebo-controlled trials of antifibrotic-directed therapies in idiopathic pulmonary fibrosis (IPF), examining FVC decline, treatment discontinuation, and mortality.
Platelet-rich plasma for knee osteoarthritis: a systematic review and meta-analysis of structural outcomes.
This systematic review and meta-analysis assessed imaging-based structural outcomes after platelet-rich plasma (PRP) treatment in people with knee osteoarthritis.
Anaesthetic Management of a Child with Chromosome 7q32.1 Microdeletion Undergoing Ligation of Patent Processus Vaginalis.
A six-year-old boy with chromosome 7q32.1 microdeletion, autism spectrum disorder, attention deficit hyperactivity disorder, hypotonia and asthma underwent elective ligation of a patent processus vaginalis under general…
Pulmonary embolism mimicking myocardial ischemia in an Emergency Department.
A man in his seventies presented to the emergency department with sudden central chest pain radiating to both arms and diaphoresis, raising concern for myocardial ischemia.
Clinical and radiographic success of bioflex versus stainless steel crowns using the hall technique in primary molars: a 12-month randomized controlled trial.
This two-arm randomized controlled trial compared BioFlex crowns (BFCs) with stainless-steel crowns (SSCs), both placed using the Hall Technique, in healthy children aged 4–6 years with carious mandibular second primary…
Tuberculosis-Associated Longitudinally Extensive Transverse Myelitis.
A 51-year-old man with a year of chronic non-productive cough and about 20 days of fever and headache presented with encephalopathy but no focal neurological deficits.
Agreement Between In-Person and Telephone Application of the Informant Questionnaire on Cognitive Decline in the Elderly.
This methodological study assessed agreement between in-person and telephone administration of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), completed by caregivers or family members of older…
Avoiding Diagnostic Overshadowing: A Case Series on Cervical Myelopathy in Patients with Fibromyalgia.
Three patients referred to a multidisciplinary chronic pain clinic for fibromyalgia evaluation had substantial physical and neurological impairment.
Maternal and Neonatal Complications in Pregnant Women With Polyendocrine Metabolic Ovarian Syndrome: A Nested Prospective Cohort Study.
This prospective nested cohort study examined associations between polyendocrine metabolic ovarian syndrome (PMOS) and pregnancy outcomes among 3,645 pregnant women with risk factors for hyperglycemia enrolled in an…
Safety and immunogenicity of the 24-valent pneumococcal conjugate vaccine in healthy Chinese adults: two single-center, randomized, double-blind Phase 1 and Phase 2 trials.
Two single-center, randomized, double-blind Phase 1 and Phase 2 trials assessed the safety and immunogenicity of a 24-valent pneumococcal conjugate vaccine (PCV24) in healthy Chinese adults aged 18 years or older.
A case of lysozyme-induced nephropathy with improved renal function following treatment for chronic myelomonocytic leukemia.
A 75-year-old man with longstanding diabetes presented with weight loss and progressive anemia and was diagnosed with chronic myelomonocytic leukemia (CMML).
Combined transcutaneous electrical nerve stimulation and low-level laser photobiomodulation for postoperative pain after cesarean section: A randomized controlled trial.
This randomized controlled trial compared combined transcutaneous electrical nerve stimulation (TENS) and low-level laser photobiomodulation (PBM) with TENS alone, placebo, and control for postoperative recovery after…
Bolus-only versus bolus plus continuous infusion hydromorphone for refractory cancer pain: a prospective, multicenter, randomized noninferiority trial.
This prospective, multicenter, randomized noninferiority trial compared bolus-only patient-controlled intravenous hydromorphone analgesia with bolus plus continuous infusion in patients with refractory cancer pain.
Patterns and predictive factors of hearing loss following microvascular decompression for hemifacial spasm: a systematic review.
This systematic review and meta-analysis assessed the prevalence, patterns, and potential risk factors for hearing loss after microvascular decompression for hemifacial spasm.
Antidopaminergic Medications and Clinical Outcomes in Huntington Disease: Evidence From the PROOF-HD Placebo-Controlled Trial.
This post hoc analysis of the placebo arm of the randomized PROOF-HD trial examined associations between antidopaminergic medication (ADM) use and clinical outcomes in adults with Huntington disease.
Clinical performance of resin infiltration and different sealant modalities in noncavitated pits and fissures: a split-mouth randomized controlled trial.
This split-mouth randomized controlled trial compared resin infiltration, two sealant approaches, and their combination for noncavitated occlusal lesions in 128 permanent molars from 32 children aged 7–14 years.
Clinical safety, tolerability, and efficacy of fospropofol disodium for sedation: a systematic review.
This systematic review and meta-analysis assessed randomized trials of fospropofol for procedural and ICU sedation. It included 10 studies: six procedural-sedation trials and four ICU-sedation trials.
Minimally invasive management of pulmonary artery bleed in robotic left upper lobectomy.
A patient undergoing robotic left upper lobectomy for a Pancoast tumour developed an intraoperative pulmonary artery bleed.
Prediction of death by neurologic criteria in patients with non-traumatic acute brain injury: a systematic review and meta-analysis.
This systematic review and meta-analysis examined predictors of death by neurologic criteria (DNC) after non-traumatic acute brain injury.
Firstline treatment with ruxolitinib versus best available therapy in patients with polycythemia vera: results from the randomized RuxoBEAT trial.
The multicenter randomized RuxoBEAT trial compared first-line ruxolitinib (RUX) with best available therapy (BAT) in patients with polycythemia vera.
Simple Site, Serious Sequelae: Septic Emboli from a Peripheral Cannula.
A young woman developed right arm pain and pleuritic chest pain after a recent hospitalisation, with marked inflammation (CRP 296 mg/L, WCC 13.7 ×10⁹/L).
Mid-term clinical outcomes and isokinetic performance after primary total knee arthroplasty within a modified ERAS protocol: a single-blinded randomized controlled trial.
This prospective, single-blinded randomized controlled trial compared a modified Enhanced Recovery After Surgery (ERAS) protocol with conventional perioperative care in 58 patients undergoing primary total knee…
Combined Chatbot and Counselor Support for Smoking Cessation in China: A Pilot, Mobile-Based, Randomized Controlled Trial.
This two-arm, community-based randomized pilot trial in China assessed chatbot-supported smoking cessation and whether adding personalized counselor support might improve outcomes.
The effect of telephone-based education and counselling on stoma adjustment and complication severity in individuals with a colostomy: a randomised controlled trial.
This randomised controlled trial evaluated telephone-based education and counselling for people with a colostomy, compared with routine stoma care.
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