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2000 articles
October 202624
Association between chronic opioid exposure and cardiovascular disease: a systematic review and meta-analysis.
This systematic review and meta-analysis examined associations between chronic opioid exposure—including opium use, opioid use disorder, and prescription opioids—and cardiovascular disease in human studies.
Treatment of Progressive Multifocal Leukoencephalopathy With Third-Party Allogeneic BK Virus T Cells.
This single-center phase 2 study evaluated third-party, partially HLA-matched BK virus-specific T cells in 37 patients with progressive multifocal leukoencephalopathy (PML), including 23 with hematologic malignancy.
IMPROVEMENT OF MACULOPATHY ASSOCIATED WITH CAVITARY OPTIC DISK ANOMALIES TREATED WITH TOPICAL ANTIGLAUCOMA MEDICATIONS.
Two young women developed worsening visual acuity associated with serous retinal detachment and maculopathy in the setting of cavitary optic disk anomalies.
Familial Glioma in a Father and Son: Integrated Genomic and Multi-compartment Proteomic Profiling.
A 60-year-old father and his 35-year-old son presented with gliomas. The father’s tumor was glioblastoma, IDH-wildtype, WHO grade 4, with an unmethylated MGMT promoter; the son’s was astrocytoma, IDH-mutant, WHO grade…
METALLIC RETINAL ARTERY EMBOLUS AFTER PIPELINE EMBOLIZATION DEVICE.
A 41-year-old woman who had undergone two Pipeline embolization device procedures for a left ophthalmic artery aneurysm was referred after an incidental refractile object was seen in the left macula.
COLOBOMA ASSOCIATED WITH VACTERL CHARACTERIZED BY ULTRA-WIDEFIELD OPTICAL COHERENCE TOMOGRAPHY.
A 34-week-old infant admitted for repair of type C tracheoesophageal fistula with esophageal atresia and management of pelviectasis and low conus medullaris underwent routine retinopathy of prematurity screening.
IDIOPATHIC ACUTE EXUDATIVE POLYMORPHOUS VITELLIFORM MACULOPATHY-CASE SERIES AND EXTENDED FEATURES.
Three subjects with idiopathic acute exudative polymorphous vitelliform maculopathy had bilateral localized serous macular detachments that coalesced into yellow-white vitelliform deposits with a hyperautofluorescent…
Real-Time Electronic Patient-Reported Outcome Monitoring With Digital Triage and Care-Team Integration in Early Breast Cancer: ENABLE Randomized Controlled Trial.
The multicenter, open-label ENABLE randomized controlled trial compared weekly electronic patient-reported outcome (ePRO) screening with rule-based triage and care-team alerts against an active app-based support…
Bilateral Iatrogenic Pneumothorax After Acupuncture in a 26-Year-Old Woman Presenting With Cough, Pleuritic Chest Pain, and Tachycardia: A Case Report.
A 26-year-old woman presented two days after trapezius-region acupuncture with persistent cough, pleuritic chest pain, and difficulty taking a full breath; she had coughed during the needling.
Subgroup Analysis of Pooled Phase 3 Efficacy Data From Two Randomized Trials of Gepotidacin Versus Nitrofurantoin in Uncomplicated Urinary Tract Infections (EAGLE-2 and EAGLE-3) Including Participants With Uropathogens Not-Susceptible to Nitrofurantoin.
This pooled subgroup analysis of two phase 3 randomized trials compared gepotidacin with nitrofurantoin in female participants aged ≥12 years with uncomplicated urinary tract infections.
IDIOPATHIC RETINITIS VASCULITIS ANEURYSMS AND NEURORETINITIS (IRVAN) TREATED WITH ADALIMUMAB: A CASE REPORT.
An adolescent with idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) was initially treated with panretinal photocoagulation and intravitreal ranibizumab in both eyes.
Comparative Effectiveness of Digital Exercise-Based Interventions for Improving Balance in Older Adults: Systematic Review and Network Meta-Analysis With GRADE Certainty of Evidence.
This systematic review and network meta-analysis compared five digital exercise-based approaches with conventional exercise (CE) and no treatment (NT) for balance in older adults.
Acute pericarditis caused by Kocuria kristinae with successful withdrawal from hemodialysis: a case report.
A 47-year-old man developed dialysis-dependent acute kidney injury after severe heatstroke. About a month later, imaging showed a marked increase in cardiothoracic ratio, and echocardiography demonstrated a substantial…
Home-based nurse-led self-management support for heart failure: a randomized controlled trial.
This parallel-group randomized controlled trial assessed a 12-week, nurse-led home programme of tailored self-management support and follow-up for adults aged 40–75 years with NYHA class I–III heart failure and ejection…
INTRARETINAL SCLEROCHOROIDAL VESSELS IN EYES WITH SEVERE CHORIORETINAL THINNING: HYPOTHESIS ON BRUCH's MEMBRANE FAILURE.
A retrospective case series described six eyes with advanced chorioretinal thinning from varied causes, including pathologic myopia, iatrogenic staphyloma, chronic anti-VEGF exposure, and nonmyopic macular atrophy.
Rapid-Onset Subacute Combined Degeneration After Short-Term, High-Dose Nitrous Oxide Use.
The title identifies a case of rapid-onset subacute combined degeneration (SCD) after short-term, high-dose recreational nitrous oxide use.
Abscopal-like Regression of Lung Metastases After Near-infrared Photoimmunotherapy Plus Nivolumab in Laryngeal Carcinoma.
A man in his 60s with recurrent laryngeal squamous cell carcinoma, base-of-tongue involvement, and multiple pulmonary metastases had progressed after several treatments, including platinum- and pembrolizumab-containing…
OPTIC DISK PIT: A TRIGGER FOR SECONDARY MULTIPLE EVANESCENT WHITE DOT SYNDROME.
A 41-year-old man with a right optic disk pit presented with right-eye visual loss and photopsia; visual acuity was 20/100.
Recurrent Nodular Lymphocyte Predominant Hodgkin Lymphoma with Diagnostic Evolution Over Two Decades.
A 51-year-old man had a nearly 20-year history of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), with multiple relapses and prolonged remissions.
HYDROXYCHLOROQUINE TOXICITY WITH SHORT DURATION OF HYDROXYCHLOROQUINE USE AND UNILATERAL BULL's EYE MACULOPATHY.
A 77-year-old Japanese woman presented with years of gradually worsening vision in her right eye. She had rheumatoid arthritis and had taken hydroxychloroquine 200 mg for five years, approximately 20 years earlier.
WHIPLASH MACULOPATHY: STRUCTURAL SEQUELAE AND THE CORRESPONDING VISUAL IMPAIRMENT, DOCUMENTED WITH OPTICAL COHERENCE TOMOGRAPHY.
A 55-year-old woman developed reduced vision in her left eye after a head-on collision. Examination showed subtle retinal pigment epithelium disruption; OCT demonstrated neurosensory detachment and intraretinal cysts.
Pseudodominant inheritance in paraplegin (SPG7)-associated CPEO-ataxia syndrome.
A 47-year-old man presented with progressive external ophthalmoplegia, ptosis, gait disturbance and spasticity. Over ten years, he developed slowly progressive spastic ataxia with ocular motor involvement and neurogenic…
Targeted BRAF /MEK inhibition as a salvage therapy for patients with metastatic melanoma harboring a BRAF L597R mutation: two case reports and review of the literature.
Two patients with metastatic melanoma harboring the BRAF L597R mutation had rapid clinical deterioration and disease progression after dual immune checkpoint inhibition.
Obesity and perioperative outcomes of robotic-assisted surgery for endometrial cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis compared perioperative outcomes after robotic-assisted surgery for endometrial cancer in patients classified as obese or non-obese by the original studies.
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