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2000 articles
October 202624
Two Older Adult Patients With Anorexia and Cachexia Following Refractory Mycobacterium avium-intracellulare Complex Pulmonary Disease Given Acupuncture Treatment to Improve Appetite and Food Intake.
Two older adults with refractory cavitary Mycobacterium avium-intracellulare complex pulmonary disease developed severe anorexia, dyspnea associated with eating, and cachexia.
Long-term remission of severe psoriasis following CD19-directed chimeric antigen receptor T-cell therapy for follicular lymphoma.
A 60-year-old woman with a 49-year history of severe plaque psoriasis received autologous CD19-directed CAR-T therapy for follicular lymphoma.
Cost-effectiveness of recommended interventions for managing low back pain: A systematic review.
This systematic review assessed the cost-effectiveness of guideline-recommended interventions for non-specific low back pain compared with usual care.
The follicular microbiome in hair-follicle-associated inflammatory diseases: a systematic review.
This systematic review qualitatively synthesized culture-independent studies of the bacterial hair-follicle microbiome in inflammatory hair-follicle-associated diseases.
Three-week ileostomy closure after colorectal surgery: a multicenter randomized trial of technical and postoperative outcomes.
This prospective multicenter randomized trial compared ileostomy closure at 3 weeks with conventional delayed closure in 224 patients after restorative colorectal resection.
STRONG prehabilitation before elective ventral hernia repair: Learnings from recruitment challenges in a randomized controlled trial.
The multicentre, parallel-group STRONG-Hernia randomised controlled trial assessed intensive lifestyle prehabilitation before elective ventral hernia repair in adults with at least one risky smoking, nutrition, alcohol…
Disruption of the N-terminal domain in a STAT3 hyper-IgE syndrome variant causes disease by sequestering STAT3 in the cytoplasm.
A patient with a STAT3 R31Q variant presented with disseminated invasive aspergillosis involving the brain and lung, bronchiectasis, and elevated serum IgE, without nonimmune manifestations of hyper-IgE syndrome.
Permissive Blood Pressure Targets in Pediatric Critical Care: The PRESSURE Randomized Clinical Trial.
The multicenter, unblinded pragmatic randomized PRESSURE trial compared a permissive mean arterial pressure (MAP) target (greater than the fifth percentile for age) with usual physician-set targets in hypotensive…
Assessing stigma and perceptions of respectful care in Malawi's index case testing program: Findings from a cluster randomized controlled trial.
This cluster randomized controlled trial assessed whether enhanced stigma-reduction training improved healthcare worker (HCW) attitudes and client experiences in Malawi’s HIV index case testing program.
Ravulizumab monotherapy for anti-CFH antibody-associated aHUS in an elderly patient: a case report highlighting individualized clinical decision-making.
An 85-year-old man presented with acute kidney injury, thrombocytopenia, microangiopathic hemolytic anemia, and severe hypertension.
Fertility Treatment and Risk of Melanoma: A Certainty-Rated Systematic Review and Meta-Analysis of 3,733,499 Women.
This certainty-rated systematic review and random-effects meta-analysis examined observational evidence on fertility treatment and incident melanoma in women.
Are intervention effects on fruit and vegetable intake maintained after 48 months of follow-up? A randomised controlled community trial.
This randomised controlled community trial assessed whether increases in fruit and vegetable (FV) intake after a 7-month transtheoretical model-based intervention were maintained among users of a Brazilian primary…
Does the "switch the plane" strategy improve outcomes? Anterior vs. posterior repair for recurrence after prior inguinal hernia repair: a systematic review and meta-analysis.
This systematic review and meta-analysis examined outcomes of recurrent unilateral inguinal hernia repair by operative plane, including comparative studies of posterior versus repeat anterior repair after prior anterior…
From Bench to Bedside: Evaluating the Accuracy of Clinical Sensory Testing in Detecting Somatosensory Disorders. A Systematic Review.
This systematic review assessed the diagnostic accuracy of clinical sensory tests (CSTs) for somatosensory disorders across populations and conditions, comparing test results with reference standards.
Safety of low lipoprotein(a) levels: the FOURIER trial.
This analysis of the randomized, multicentre FOURIER trial examined associations between lipoprotein(a) [Lp(a)] levels and safety outcomes in patients with stable atherosclerotic cardiovascular disease receiving…
Dose-Response Effects of Exercise Training on Circulating Brain-Derived Neurotrophic Factor (BDNF): A Systematic Review and Meta-analysis of Randomised Controlled Trials.
This systematic review and meta-analysis pooled randomised controlled trials comparing chronic exercise with non-exercising controls to assess circulating brain-derived neurotrophic factor (BDNF).
An Individual Meta-Analysis of Psychological Treatments for Mood and Personality Disorders Using the Severity Diagnostic System of ICD-11.
This individual patient meta-analysis examined whether ICD-11 personality-disorder severity was associated with short-term outcomes in 1,384 patients from four randomised trials of psychological treatments, mainly…
Music-based interventions for people with kidney failure undergoing haemodialysis.
This Cochrane systematic review and meta-analysis assessed randomised trials of music-based interventions in people with kidney failure receiving haemodialysis.
A Short Evidence-Based, Belief-Focused Educational Video Improves Back Pain Beliefs but Not Lifting Behaviour in Healthy Office Workers: An Exploratory Randomised Controlled Trial.
This assessor-blind exploratory randomised controlled trial assigned 50 healthy office workers to a brief video about back pain beliefs and management or an anatomy-video control.
Consequences of opioid exposure in disease-free cancer survivors: A systematic literature review.
This systematic literature review examined the consequences of persistent opioid exposure after curative-intent treatment in disease-free cancer survivors.
The combination of simethicone and N-acetylcysteine in lidocaine ice popsicle compared with lidocaine ice popsicle alone in patients undergoing unsedated esophagogastroduodenoscopy: A prospective double-blind randomized controlled trial.
This single-centre, prospective, double-blind randomised controlled trial compared a lidocaine ice popsicle containing simethicone and N-acetylcysteine (NAC) with a conventional lidocaine popsicle in 374 adults…
Individual Effects of Angiotensin II Receptor Blockers on Major Adverse Cardiovascular Events: A Systematic Review and Network Meta-Analysis.
This systematic review and random-effects network meta-analysis compared angiotensin II receptor blockers (ARBs) for cardiovascular outcomes in randomized trials not primarily designed to study heart failure.
Outdoor risky play and health-related outcomes in children aged 3-12 years: A mixed-methods systematic review.
This mixed-methods systematic review synthesised evidence on outdoor risky play and health outcomes in children aged 3–12 years. It included 74 studies: 48 quantitative, 19 qualitative and 7 mixed-methods.
Adjunctive topical mitomycin C during endoscopic dilation for pediatric caustic esophageal stricture: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis assessed topical mitomycin C (MMC) added to endoscopic dilation for caustic esophageal stricture in children.
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