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1502 articles
October 202624
Miro1 mediates skeletal muscle insulin resistance in type 2 diabetes.
This study investigated whether mitochondrial Rho GTPase 1 (Miro1) contributes to skeletal muscle insulin resistance in type 2 diabetes (T2D).
Effectiveness of digital educational technologies in knowledge acquisition for adolescent health promotion: a systematic review.
This systematic review assessed whether digital educational technologies improve health-promotion knowledge among adolescents.
Oral mucous membrane pemphigoid as a window to systemic autoimmunity: two cases associated with rheumatoid arthritis and Sjögren's disease.
Two women presented with oral mucous membrane pemphigoid (MMP) in the setting of systemic autoimmunity. A 68-year-old woman with longstanding rheumatoid arthritis had recurrent oral ulcerations confirmed as MMP on…
Robotic resection of cardiac papillary fibroelastoma guided by three-dimensional transesophageal echocardiography: a case report.
A patient was diagnosed with a papillary fibroelastoma involving the mitral valve. Three-dimensional transesophageal echocardiography (3D TEE) was used to characterize the suspected lesion and assess its anatomy…
Tranexamic acid in laparoscopic sleeve gastrectomy: bleeding control amid thrombotic concerns and hemodynamic instability: a randomized double-blinded clinical trial.
This randomized, double-blinded clinical trial assessed tranexamic acid (TXA) for perioperative bleeding prevention in 185 patients with morbid obesity undergoing elective laparoscopic sleeve gastrectomy.
Safety and effectiveness of the Vertex Pulmonary Embolectomy System in acute intermediate-risk pulmonary embolism: the SPIRARE II pivotal trial.
SPIRARE II was a prospective, single-arm, multicentre pivotal trial evaluating the Vertex Pulmonary Embolectomy System for aspiration thrombectomy in patients with acute intermediate-risk pulmonary embolism.
Coronary artery disease management in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis of randomised trials compared coronary revascularisation strategies in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI).
Conventional Skull Base Chordoma in a Ugandan Adult Male, Presenting with Prolonged Headache: A Case Report.
A 49-year-old man had more than a year of intermittent, progressively worsening headache and reported an episode of facial numbness, although facial sensation and the remainder of his neurological examination were…
Clinical Recovery Following Conservative Management of a Large Presumed Brain Abscess with a Concomitant Streptococcus intermedius Lung Abscess in a Severely Malnourished Young Adult in a Resource-Limited Setting: A Case Report.
A severely malnourished 22-year-old man presented with progressive left-sided weakness after weeks of productive cough, fever, and weight loss. Examination showed impaired consciousness and flaccid hemiplegia.
Comparative Pharmacokinetics and Safety of Orally Disintegrating and Conventional Tablet Formulations of Zastaprazan in Healthy Subjects.
This open-label, randomized, single-dose, three-period crossover study compared the pharmacokinetics and safety of 20 mg zastaprazan orally disintegrating tablets (ODTs), taken with or without water, with the…
Hepatitis A Virus (HAV) Recurrence and De Novo Hepatitis A Acquired at Time of Liver Transplantation: Comparison of Graft HAV Infection and Viral Kinetics.
Two liver transplant recipients developed hepatitis A virus (HAV) infection of the graft in different settings. A recipient transplanted for HAV-related acute liver failure had a rapid fall in serum HAV RNA after…
The Impact of Anaesthesia Method on the Use of Anaesthesia Department Resources in Total Knee Arthroplasty.
This randomised controlled trial compared spinal anaesthesia with general anaesthesia using total intravenous anaesthesia in 395 patients undergoing total knee arthroplasty.
Full-spectrum LED screen-bar lighting as an adjunct to artificial tears in visual display terminal-related dry eye: a randomized study.
This prospective, randomised, single-centre study assessed whether full-spectrum screen-bar lighting adds benefit to artificial tears in 66 participants with newly diagnosed visual display terminal-related dry eye and…
Magnetic resonance imaging vs computed tomography for baseline imaging evaluation in acute basilar artery occlusion.
This post hoc analysis of the ATTENTION trial compared baseline MRI with CT for patient selection in acute basilar-artery occlusion.
An Integrated Approach to MSI-High Colorectal Cancer Therapy in a Young Patient: A Clinical Case.
A 16-year-old male underwent appendectomy for presumed appendicitis, but persistent postoperative bowel obstruction led to CT detection of a descending-colon tumor and emergency Hartmann’s procedure.
Advances in physiotherapy for chronic low-back pain: a level I systematic review.
This level I systematic review qualitatively examined randomised controlled trials of physiotherapy programmes for chronic low-back pain (cLBP), identified through searches of PubMed, Web of Science and Embase in August…
Non-Relapse Mortality With Bispecific Antibodies in Hematologic Malignancies: A Dual Systematic Review and Pharmacovigilance Analysis.
This systematic review and meta-analysis, supplemented by a pharmacovigilance analysis of FAERS, assessed non-relapse mortality (NRM) and other toxicities with bispecific antibodies in relapsed/refractory hematologic…
Patient-Reported Outcomes after Distal Radius Fractures Differ Across Geographic and Cultural Populations: A Global Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis examined whether patient-reported outcomes after volar locking-plate fixation of adult distal radius fractures varied across cultural and geographic populations.
Gene-based association analysis of depression risk among European ancestry Parkinson's disease patients.
This gene-based association analysis and meta-analysis examined common and low-frequency genetic variants related to depression among European-ancestry patients with Parkinson’s disease (PD) in three population-based…
Tocilizumab for active rheumatoid arthritis in a patient with concomitant primary biliary cholangitis: a case based review.
A 59-year-old woman presented with highly active, seropositive rheumatoid arthritis and marked cholestatic biochemical activity. Evaluation identified active primary biliary cholangitis without advanced liver fibrosis.
Reducing period poverty through interventions, innovations, policies and multilevel barriers and facilitators: A systematic review.
This systematic review synthesised evidence on menstrual health interventions, innovations, policies, and barriers and facilitators related to period poverty in low-, middle-, and high-income countries.
Gamma-irradiated amniotic membrane graft as an adjuvant to posterior colporrhaphy: an exploratory prospective single-arm clinical trial.
This exploratory prospective, single-arm pilot clinical trial evaluated gamma-irradiated amniotic membrane grafting during posterior colporrhaphy in 25 women with posterior compartment prolapse.
Switching from Intravenous to Subcutaneous Infliximab in Children with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis synthesized six independent, largely observational cohorts of children with inflammatory bowel disease who switched from intravenous to subcutaneous infliximab (n = 173).
Microsurgical clipping versus Woven EndoBridge embolization for intracranial aneurysms: a systematic review and meta-analysis.
This systematic review and meta-analysis compared microsurgical clipping with Woven EndoBridge (WEB) embolization for ruptured and unruptured intracranial aneurysms.
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