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1502 articles

October 202624

Clinical ResearchOtolaryngology (ENT)

Adenotonsillectomy for children with mild sleep-disordered breathing: who benefits?

This secondary analysis of a 12-month, multicentre randomised trial examined children aged 3.0–12.9 years with mild sleep-disordered breathing, comparing early adenotonsillectomy (eAT) with watchful waiting and…

SleepOct 13, 2026Read summary
Case ReportNeurosurgery

Stroke thrombectomy of a mural thrombus in a severe dolichoectatic basilar artery with double parallel large stent retrievers and Sofia 88.

An older adult presented with severe acute ischemic stroke from a mural thrombus on the posterior wall of the mid-basilar artery.

J Neurointerv SurgOct 13, 2026Read case
Clinical ResearchPediatrics

Impact of a Dynamic Visualized Pain Assessment Tool on Pediatric Pain Management: A Stepped-Wedge Cluster Randomized Trial.

This stepped-wedge cluster randomized trial evaluated a dynamic visualized pain assessment tool across five clinical wards, involving 15 infants and 45 video segments spanning baseline, procedural pain, and…

J Vis ExpOct 13, 2026Read summary
Clinical ResearchCardiology

Early Discharge Strategy Including Subcutaneous Furosemide in Hospitalized Heart Failure.

This multicenter, open-label, randomized active-controlled trial in the United Kingdom studied 172 patients hospitalized with heart failure who still required parenteral diuretics.

J Am Coll CardiolOct 13, 2026Read summary
Clinical ResearchPulmonology

Machine Learning, Radiomics, and Clinical Models Predicting Checkpoint Inhibitor Pneumonitis in Lung Cancer: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed machine-learning, radiomics, deep-learning, and clinical models for predicting checkpoint inhibitor pneumonitis in people with lung cancer.

J Vis ExpOct 13, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Premenstrual Syndrome and Premenstrual Dysphoric Disorder: A Systematic Review of Academic Performance and Well-Being in University Students.

This systematic review synthesized 11 observational, cross-sectional studies of female medical and health sciences students published between January 2014 and December 2024.

J Vis ExpOct 13, 2026Read summary
Case ReportGastroenterology

PTCD and Peroral Electronic Cholangioscopy with Holmium Laser Lithotripsy for CBD Stones in a Super-Elderly Patient Post-Billroth II Gastrojejunostomy.

The management of impacted common bile duct stones in patients with prior Billroth II gastrectomy poses unique challenges. Altered gastrointestinal anatomy renders duodenoscope passage and biliary cannulation during…

J Vis ExpOct 13, 2026Read case
Case ReportPhysical Medicine & RehabilitationOpen access

Integrated physical, cognitive and psychological rehabilitation following multiple ACL reconstructions in a professional handball player: a case report.

A 31-year-old professional handball player with two ACL reconstructions, meniscal repairs, a postoperative knee infection, and multiple arthroscopic procedures had persistent knee instability, pain, and psychological…

J Med Case RepOct 13, 2026Read case
Case ReportPediatricsOpen access

Successful management of long-term venovenous ECMO for severe PARDS in a child with acute lymphoblastic leukemia.

A 5-year-old boy with low-risk B-cell acute lymphoblastic leukemia developed severe, refractory pediatric acute respiratory distress syndrome during induction therapy, with profound hypoxemia.

J Artif OrgansOct 13, 2026Read case
Case ReportNeurologyOpen access

Hemi-see-saw nystagmus with superimposed pendular oculopalatal tremor: case report and systematic review.

A 30-year-old man with a pontomedullary arteriovenous malformation presented with pendular hemi-see-saw nystagmus, right one-and-a-half syndrome, gaze-evoked nystagmus, ocular tilt reaction, incomplete Horner syndrome…

J NeurolOct 13, 2026Read case
Case ReportHematologyOpen access

Myeloid neoplasm with PDGFRA rearrangement presenting in blast-phase with basophilia.

An adult man from Southern Africa presented with progressive fatigue. Blood morphology showed marked basophilia and 21% myeloblasts, with flow cytometry supporting a provisional diagnosis of acute myeloid leukaemia with…

J HematopOct 13, 2026Read case
Clinical ResearchOncology (Medical)Open access

Application of a concise video to improve patient understanding of tumor genomic testing in community and academic practice settings.

This multicenter clinical trial evaluated a 3–4 minute educational video for patients undergoing standard-of-care tumor genomic testing (TGT), across cancer types and academic and community settings.

PLoS OneOct 13, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Factors associated with 1-year health-related quality of life after neck-specific exercise in chronic whiplash-associated disorders: an exploratory secondary analysis of a randomized controlled trial.

This exploratory secondary analysis of a prospective, assessor-blinded, multicentre randomised trial examined factors associated with health-related quality of life (HRQoL) after neck-specific exercise in 140 people…

BMC Musculoskelet DisordOct 13, 2026Read summary
Case ReportOphthalmologyOpen access

Extensive recurrent pterygium following photorefractive keratectomy: a case report.

A healthy 39-year-old man developed an extensive recurrent pterygium three months after uneventful photorefractive keratectomy (PRK), having undergone primary pterygium surgery two months before PRK.

BMC OphthalmolOct 13, 2026Read case
Clinical ResearchDermatology

Comparative efficacy of topical garlic extract and 20% podophyllin solution in the treatment of female genital warts: a triple-blind randomized clinical trial.

This triple-blind randomized clinical trial compared topical 5% garlic extract with 20% podophyllin in 74 women with genital warts, applied weekly for four weeks.

J Dermatolog TreatOct 12, 2026Read summary
Clinical ResearchCardiology

Impact of Extent of Coronary Artery Disease in Transcatheter Aortic Valve Replacement: A PRO-TAVI Substudy.

This post hoc substudy of the multicentre randomised PRO-TAVI trial examined whether coronary disease complexity, measured by SYNTAX score, was associated with outcomes among 466 patients with significant coronary…

JACC Cardiovasc IntervOct 12, 2026Read summary
Clinical ResearchCardiology

Immediate Versus Staged Complete Revascularization in Multivessel Disease and STEMI: A Meta-Analysis of Randomized Trials.

This frequentist meta-analysis of four multicentre randomised trials compared immediate with staged complete revascularization in 2,651 patients with STEMI and multivessel disease.

JACC Cardiovasc IntervOct 12, 2026Read summary
Clinical ResearchCardiology

Occlusion-Focused Triage vs Very-High-Risk NSTEMI Criteria: A DIFOCCULT-3 Substudy.

This substudy of the multicenter, cluster-randomized DIFOCCULT-3 trial compared occlusion/nonocclusion (OMI/NOMI) classification with the conventional STEMI/NSTEMI framework and guideline-defined very-high-risk NSTEMI…

JACC Cardiovasc IntervOct 12, 2026Read summary
Clinical ResearchInfectious Diseases

Predictors of immunological non-response despite virological suppression in people living with HIV on antiretroviral therapy: A systematic review and meta-analysis.

This systematic review and meta-analysis examined clinical, demographic and molecular predictors of inadequate CD4+ T-cell recovery despite viral suppression on antiretroviral therapy in people living with HIV.

PLoS OneOct 12, 2026Read summary
Clinical ResearchEndocrinology

Effectiveness of a self-management intervention on clinical outcomes among patients with type 2 diabetes at high risk for Diabetic Kidney Disease: A Randomised Controlled Trial.

This prospective, two-arm randomised controlled trial at a tertiary hospital in China evaluated a structured self-management programme in 134 adults with type 2 diabetes classified as at high risk of diabetic kidney…

PLoS OneOct 12, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Menstrual health challenges and associated barriers among tribal adolescent girls in India: A systematic review.

This systematic review synthesised quantitative, qualitative and mixed-methods research on menstrual health among tribal adolescent girls in India.

PLoS OneOct 12, 2026Read summary
Case ReportPathology (Anatomic & Clinical)

Hodgkin Lymphoma With Sarcoid-Like Reaction: Importance of Clinicopathological Correlation in Granulomatous Lymphadenopathy.

A 63-year-old man with systemic lymphadenopathy had a cervical lymph node biopsy showing epithelioid granulomas but no identifiable neoplastic cells, prompting an initial suspicion of sarcoidosis.

Am J Case RepOct 12, 2026Read case
Case ReportNephrologyOpen access

Early-onset autosomal dominant distal renal tubular acidosis caused by a de novo SLC4A1 R589C variant with growth failure and rickets.

A Japanese boy had marked growth failure from 6 months of age and was diagnosed with autosomal dominant distal renal tubular acidosis at 27 months.

CEN Case RepOct 12, 2026Read case
Case ReportPathology (Anatomic & Clinical)Open access

A case of immunofluorescence-negative light chain deposition disease diagnosed by mass spectrometry.

A 53-year-old man with kidney dysfunction and edema had nodular glomerular lesions on biopsy, but immunofluorescence did not show immunoglobulin or light-chain deposits.

CEN Case RepOct 12, 2026Read case

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