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1502 articles

October 202624

Clinical ResearchGastroenterology

Finite Versus Indefinite Nucleos(t)ide Analogue Therapy in HBeAg‑Negative Chronic Hepatitis B: Meta‑Analysis of Randomized Trials.

This meta-analysis evaluated the efficacy and safety of finite versus continuous nucleos(t)ide analogue therapy in HBeAg-negative adults with chronic hepatitis B.

J Viral HepatOct 7, 2026Read summary
Clinical ResearchPediatrics

Synbiotic supplementation leads to gut microbiome communities with functional capacity linked to better brain white matter development in preterm infants.

This secondary analysis of a randomized controlled trial examined whether daily synbiotic and nutritional supplementation could shape gut microbiome function in very and extremely preterm infants, and how those…

Gut MicrobesOct 7, 2026Read summary
Clinical ResearchDermatology

Janus kinase inhibitors in the management of lichen planus: a systematic review.

Lichen planus (LP) is a chronic, lymphocytic, inflammatory skin disorder that can affect the skin, hair follicles, nails, and mucous membranes. It has limited treatment options.

Ann MedOct 7, 2026Read summary
Clinical ResearchPsychiatry

Early interventions for primary care patients with stress-related mental ill health: a randomised controlled non-inferiority trial of a nurse-led collaborative care intervention versus cognitive behavioural therapy.

This randomised controlled non-inferiority trial compared nurse-led collaborative care (CC) with psychologist-guided self-help cognitive behavioural therapy (GSH-CBT) in 172 adults with mild to moderate stress-related…

BMJ Ment HealthOct 7, 2026Read summary
Case ReportOncology (Medical)

Atypical presentations of Lhermitte's sign after treatment for human papillomavirus-associated oropharyngeal squamous cell carcinoma.

Two patients with human papillomavirus-associated oropharyngeal squamous cell carcinoma developed Lhermitte’s sign after chemoradiotherapy.

BMJ Case RepOct 7, 2026Read case
Case ReportNeurology

Fregoli syndrome in an adolescent with Moyamoya disease.

An early adolescent with known Moyamoya disease developed acute psychosis after a febrile illness accompanied by headache and vomiting.

BMJ Case RepOct 7, 2026Read case
Case ReportHematology

Fatal haemophagocytic lymphohistiocytosis and atypical haemolytic uraemic syndrome following coronavirus disease 2019 infection.

A previously healthy woman in her early 30s developed rash, fever and arthralgia three weeks after SARS-CoV-2 infection, followed by rapidly progressive multiorgan failure.

BMJ Case RepOct 7, 2026Read case
Case ReportOphthalmology

Time to improve laboratory protocols in microbial keratitis: broad-range Internal Transcribed Spacer sequencing in refractory culture-negative keratitis.

A woman in her 60s who wore soft contact lenses developed rapidly progressive microbial keratitis that did not respond to intensive empirical treatment.

BMJ Case RepOct 7, 2026Read case
Case ReportEndocrinology

Emerging risks of health optimisation: refractory nausea associated with peptide injections reported to contain retatrutide.

A woman in her mid-20s presented with five days of persistent nausea, repeated vomiting, loose stools and markedly reduced oral intake.

BMJ Case RepOct 7, 2026Read case
Case ReportGeneral Surgery

Meckel's diverticulum leading to axial torsion and volvulus of the small bowel.

A patient presented with small-bowel obstruction caused by a giant Meckel’s diverticulum measuring 22 cm × 11 cm × 9.8 cm. The diverticulum produced mass effect and was associated with axial torsion and volvulus of the…

BMJ Case RepOct 7, 2026Read case
Case ReportHematology

Idiopathic multicentric Castleman disease in an HIV-positive child.

A preadolescent girl with HIV presented with fever and unilateral facial and neck swelling. Examination showed generalised lymphadenopathy, hepatosplenomegaly, hypertension and haematuria, initially suggesting…

BMJ Case RepOct 7, 2026Read case
Case ReportPediatrics

Facial nerve palsy and hypertension; unusual presentation of apparent mineralocorticoid excess (AME) syndrome in a paediatric patient.

A boy in early childhood presented after two days of right-sided facial palsy and was found to have severe hypertension with end-organ damage.

BMJ Case RepOct 7, 2026Read case
Case ReportOphthalmology

Acute retinal necrosis refractory to treatment.

A woman in her 60s presented with hypertensive uveitis in the right eye, followed by vitritis and retinitis. An anterior chamber sample was positive for herpes simplex virus by PCR.

BMJ Case RepOct 7, 2026Read case
Case ReportMedical Genetics

Complex presentation of neonatal arthrogryposis multiplex congenita: insights into a multifactorial disorder.

A neonate with amyoplasia-type arthrogryposis multiplex congenita had bilateral talipes equinovarus, elbow contractures, ulnar wrist deviation and clinodactyly, with mild hip dysplasia and a small atrial septal defect.

BMJ Case RepOct 7, 2026Read case
Case ReportNeurology

Staged bilateral MR-guided focused ultrasound thalamotomy in a patient with cerebral cavernous malformations.

A man in his late 60s with medication-refractory essential tremor was found on preoperative MRI to have cavernous malformations in the left caudate head and basal ganglia, with an associated developmental venous anomaly…

BMJ Case RepOct 7, 2026Read case
Case ReportHematology

In vitro correction of venom-induced coagulopathy in Daboia russelii envenomation demonstrated using tranexamic acid-modified rotational thromboelastometry.

A man in his late 40s presented soon after Russell’s viper envenomation with local signs and a prolonged modified Lee and White clotting time, despite normal prothrombin and activated partial thromboplastin times.

BMJ Case RepOct 7, 2026Read case
Case ReportOncology (Medical)

Scleral perforation in a young adult with Burkitt lymphoma.

A man in his 20s with Burkitt lymphoma receiving chemotherapy was referred for lagophthalmos and left facial nerve palsy. Weeks later, he developed acute scleral perforation.

BMJ Case RepOct 7, 2026Read case
Case ReportOtolaryngology (ENT)

Silent danger behind the forehead: Pott's puffy tumour presenting without systemic symptoms.

A man in his 50s developed progressive, painless forehead swelling despite multiple courses of antibiotics, without systemic symptoms.

BMJ Case RepOct 7, 2026Read case
Clinical ResearchGeneral Surgery

Preoperative pathways in adults with multiple long-term conditions undergoing major surgery: a systematic review.

This systematic review examined preoperative interventions, pathways and protocols for adults with multiple long-term conditions (MLTCs) undergoing major surgery.

BMJ OpenOct 7, 2026Read summary
Clinical ResearchInfectious Diseases

HIV care cascade of adolescents and young adults in sub-Saharan Africa: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed progress toward the UNAIDS 95-95-95 targets among adolescents and young adults living with HIV in sub-Saharan Africa. It included 37 studies from 13 countries.

BMJ OpenOct 7, 2026Read summary
Clinical ResearchAnesthesiology

Effects of remimazolam versus propofol on cerebral oxygenation in elderly patients undergoing prone spine surgery: study protocol for a randomised controlled trial.

This article describes the protocol for a prospective, single-centre randomised controlled trial comparing remimazolam with propofol-based total intravenous anaesthesia in elderly patients undergoing elective thoracic…

BMJ OpenOct 7, 2026Read summary
Clinical ResearchPulmonology

Manual compared to automated closed-loop oxygen control strategies in hospitalised adults: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed randomised controlled trials comparing closed-loop oxygen control (CLOC) with manual adjustment in hospitalised adults receiving noninvasive oxygen.

Eur Respir RevOct 7, 2026Read summary
Clinical ResearchGeriatrics

Dose- and modality-specific effects of exercise on BDNF and depression in middle-aged and older adults with mild cognitive impairment: A Bayesian network meta-analysis.

This Bayesian network dose-response meta-analysis examined randomized controlled trials of exercise in adults aged 50 years or older with mild cognitive impairment (MCI), assessing peripheral brain-derived neurotrophic…

PLoS OneOct 7, 2026Read summary
Case ReportDermatology

A 45-Year-Old Woman With 30-Year History of a Nodule of the Earlobe Diagnosed as Lupus Vulgaris (Cutaneous Tuberculosis).

A 45-year-old woman had a painless, intermittently itchy lesion on her right earlobe for more than 30 years. It appeared as a red, thickened plaque with yellow papules and pustules.

Am J Case RepOct 7, 2026Read case

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