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1502 articles

October 202624

Clinical ResearchAnesthesiologyOpen access

Survival outcomes following total intravenous versus volatile anesthesia in esophagogastric cancer surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis compared total intravenous anesthesia (TIVA) with volatile anesthesia in adults undergoing curative surgery for esophageal or gastric cancer.

Langenbecks Arch SurgOct 7, 2026Read summary
Clinical ResearchHematologyOpen access

T-cell-redirecting therapies in early relapsed multiple myeloma: a systematic review and network meta-analysis.

This systematic review and network meta-analysis compared T-cell-redirecting regimens in randomized phase 3 trials involving patients with multiple myeloma after at least one prior line.

J Hematol OncolOct 7, 2026Read summary
Clinical ResearchPediatricsOpen access

Short- versus long-course antibiotic therapy in non-severe CAP in children: a systematic review and meta-analysis.

This systematic review and meta-analysis compared short-course (≤ 5 days) with longer (> 5 days) antibiotic therapy for non-severe community-acquired pneumonia in immunocompetent children.

Eur J PediatrOct 7, 2026Read summary
Clinical ResearchCardiology

EACTS Expert Consensus Document on aortic valve repair and valve-sparing aortic root replacement procedures.

This EACTS Expert Consensus Document critically reviews evidence on aortic valve repair and valve-sparing aortic root replacement for aortic regurgitation and proximal thoracic aortic aneurysms across age groups.

Eur J Cardiothorac SurgOct 7, 2026Read summary
Clinical ResearchPsychiatryOpen access

Anxiety and Depression in Athletes of Different Levels Without Current Injury: A Systematic Review With Meta-Analyses.

This systematic review and random-effects meta-analysis examined anxiety and depression in athletes across competitive levels, including those without current injury.

J Athl TrainOct 7, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Efficacy of direct-acting antiviral regimens for acute HCV infection: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed interferon-free dual direct-acting antiviral regimens for acute or recently acquired HCV infection.

Virol JOct 7, 2026Read summary
Clinical ResearchDermatology

Acrokeratosis paraneoplastica (Bazex syndrome): a systematic review and quantitative analysis of 106 cases.

Acrokeratosis paraneoplastica (Bazex syndrome) is an obligate paraneoplastic dermatosis characterized by symmetrical acral psoriasiform lesions and nail dystrophy.

OncologistOct 7, 2026Read summary
Clinical ResearchOncology (Medical)

Dose response relationship of medical cannabis and symptom control in patients with pancreatic cancer: an analysis of the CANPAN trial.

This analysis of the CANPAN pilot waitlist-control randomized trial examined cannabis use, patient-reported outcome completion, and THC dose-response among 32 cannabis-naïve patients with newly diagnosed locally…

OncologistOct 7, 2026Read summary
Clinical ResearchOncology (Medical)

Chemotherapy backbone and outcomes of immune checkpoint inhibitor combinations across solid tumors: a pan-tumor network meta-analysis.

This systematic review and network meta-analysis examined phase II–III randomised trials comparing first-line immune checkpoint inhibitor (ICI) plus chemotherapy with chemotherapy alone across solid tumours, assessing…

OncologistOct 7, 2026Read summary
Case ReportNeurologyOpen access

Probable vestibular paroxysmia mimicking benign paroxysmal positional vertigo of the superior semicircular canal in the presence of a neurovascular conflict: a case report and review of the literature.

A 52-year-old woman presented with positional vertigo and was initially diagnosed with right superior semicircular canal benign paroxysmal positional vertigo (BPPV).

J Med Case RepOct 7, 2026Read case
Case ReportPsychiatryOpen access

Managing 7-Hydroxymitragynine Use Disorder with Buprenorphine-Naloxone.

A patient who had used kratom to stop illicit opioids developed tolerance and transitioned to 7-hydroxymitragynine, believing the plant-derived product was safe.

Hawaii J Health Soc WelfOct 7, 2026Read case
Case ReportAnesthesiologyOpen access

Effect of a Single Subanesthetic Dose of Esketamine on Gastrointestinal Recovery After Laparoscopic Colorectal Cancer Surgery: A Randomized, Outcome-Assessor-Blinded, Placebo-Controlled Trial.

Postoperative gastrointestinal dysfunction (POGD) and Postoperative gastrointestinal intolerance (POGI) remain a critical challenge in abdominal surgery, particularly for colorectal cancer patients undergoing…

Drug Des Devel TherOct 7, 2026Read case
Clinical ResearchRheumatology

Prospective controlled study of the recombinant zoster vaccine in autoimmune rheumatic disease: robust seroconversion despite intravenous cyclophosphamide.

This subanalysis of a prospective, randomized, placebo-controlled trial assessed recombinant zoster vaccine (RZV) responses in patients with autoimmune rheumatic disease receiving intravenous cyclophosphamide (IVCYC)…

VaccineOct 7, 2026Read summary
Case ReportNeurologyOpen access

Multiple Sclerosis During Pregnancy and the Postpartum Period: Diagnostic and Multidisciplinary Challenges in Two Cases.

The report describes two pregnant women with progressive focal neurological symptoms and brain MRI abnormalities concerning for central nervous system demyelination.

Int Med Case Rep JOct 7, 2026Read case
Case ReportHematology

Successful treatment of hairy cell leukemia with TP53 abnormality using cladribine combined with low-dose rituximab: a case report and literature review.

An elderly man with classical hairy cell leukemia (HCL) had BRAF V600E positivity, a TP53 deletion detected by fluorescence in situ hybridization, and bone marrow fibrosis.

Anticancer DrugsOct 7, 2026Read case
Case ReportOncology (Medical)

Case report: successful use of repotrectinib in a ROS1 fusion-positive lung adenocarcinoma patient with severe renal insufficiency and prior tyrosine kinase inhibitor treatment failure.

A 69-year-old woman with advanced lung adenocarcinoma harboring an SDC4–ROS1 fusion had bilateral pulmonary lesions, mediastinal lymphadenopathy, and pleural effusions.

Anticancer DrugsOct 7, 2026Read case
Clinical ResearchRadiology (Diagnostic)

Fractal radiomics as a virtual biopsy in glioma: A systematic review and meta-analysis of molecular status, radiogenomic associations, and survival outcomes.

This systematic review and meta-analysis assessed whether fractal-based imaging features can predict molecular alterations and outcomes in glioma.

J Clin NeurosciOct 7, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Adult diagnostic reference levels in computed tomography: A systematic review and analysis of regional variability.

This systematic review examined adult computed tomography diagnostic reference levels (DRLs) across regions and examination types.

Eur J RadiolOct 7, 2026Read summary
Clinical ResearchUrology

MRI-derived radiomics for prostate cancer active surveillance: a systematic review.

This PRISMA 2020 systematic review assessed MRI-derived radiomic and artificial intelligence models for selecting men with prostate cancer for active surveillance, detecting clinically significant cancer at baseline…

Eur J RadiolOct 7, 2026Read summary
Clinical ResearchPsychiatry

Effectiveness of psychosocial interventions addressing informal caregivers' mental health: an umbrella systematic review with 26,481 participants.

This umbrella systematic review and random-effects meta-analysis assessed psychosocial interventions for the mental health of informal caregivers, grouped by care recipients’ clinical conditions.

Clin Psychol RevOct 7, 2026Read summary
Clinical ResearchNeurology

Challenging historical associations and reassuring women: an updated meta-analysis of multiple sclerosis relapse risk following assisted reproductive technology.

This systematic review and random-effects meta-analysis examined whether assisted reproductive technology (ART) is associated with multiple sclerosis (MS) relapses in women with MS or incident MS in previously healthy…

Mult Scler Relat DisordOct 7, 2026Read summary
Clinical ResearchNephrology

The effects of exercise on pulmonary function and respiratory muscle strength in patients with chronic kidney disease: a systematic review and meta-analysis.

This systematic review and meta-analysis examined experimental studies of exercise and respiratory outcomes in people with chronic kidney disease across disease stages. Thirteen studies contributed to the meta-analyses.

Respir MedOct 7, 2026Read summary
Clinical ResearchCardiology

Acute effects of volume-matched isometric exercise intensity on vascular function and autonomic regulation in men with elevated blood pressure.

This randomized controlled trial examined the acute effects of high-intensity isometric exercise (HIIE) versus low-intensity isometric exercise (LIIE) on cardiovascular function in 17 men with elevated blood pressure.

Clin Physiol Funct ImagingOct 6, 2026Read summary
Clinical ResearchHematologyOpen access

Infection burden in mismatched unrelated donor hematopoietic cell transplantation: results from the ACCESS trial.

The ACCESS trial evaluated infection burden in 268 adult patients undergoing HLA-mismatched unrelated donor hematopoietic cell transplantation (HCT) with posttransplant cyclophosphamide (PTCy) for graft-versus-host…

Blood AdvOct 6, 2026Read summary

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