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1566 articles

October 202624

Clinical ResearchPulmonology

Effects of high-dose supplemental oxygen therapy on pulmonary haemodynamics at 3250 m in high-altitude residents at risk for pulmonary hypertension.

This open-label, non-randomised trial investigated the effects of high-dose supplemental oxygen therapy (SOT) on pulmonary haemodynamics in Kyrgyz highlanders at 3250 m with elevated systolic pulmonary artery pressure…

BMJ Open Respir ResOct 1, 2026Read summary
Clinical ResearchOncology (Medical)

Toripalimab consolidation after chemoradiotherapy in limited-stage small cell lung cancer: a phase II, randomized controlled study (GASTO-1052A).

This phase II randomized controlled trial evaluated the efficacy and safety of toripalimab consolidation after chemoradiotherapy in patients with limited-stage small cell lung cancer (LS-SCLC).

J Immunother CancerOct 1, 2026Read summary
Clinical ResearchHematology

Felzartamab plus lenalidomide-dexamethasone versus lenalidomide-dexamethasone for relapsed or refractory multiple myeloma: an open-label, parallel-controlled, randomised, phase 3 trial.

This phase 3 randomized trial evaluated the efficacy of felzartamab combined with lenalidomide-dexamethasone versus lenalidomide-dexamethasone alone in Chinese patients with relapsed or refractory multiple myeloma.

Lancet HaematolOct 1, 2026Read summary
Clinical ResearchHematology

Rilzabrutinib, an oral Bruton tyrosine kinase inhibitor, in patients with warm autoimmune haemolytic anaemia: a prospective, single-arm, multicentre, phase 2b safety and clinical activity study (LUMINA 2).

The LUMINA 2 study evaluated the safety and clinical activity of rilzabrutinib, a Bruton tyrosine kinase inhibitor, in adults with warm autoimmune haemolytic anaemia.

Lancet HaematolOct 1, 2026Read summary
Clinical ResearchOrthopedic Surgery

Wound dehiscence following biportal endoscopic versus microscopic spine surgery for single-level lumbar decompression: a post hoc analysis of two randomized controlled trials.

This post hoc analysis of two randomized controlled trials compared wound dehiscence rates between biportal endoscopic spine surgery (BESS) and microscopic spine surgery (MSS) in 211 patients undergoing single-level…

Neurosurg FocusOct 1, 2026Read summary
Case ReportNeurosurgery

A hypertensive response to irrigation: endoscopic repair of a ventral spinal CSF leak.

A 36-year-old woman with recurrent spontaneous intracranial hypotension due to a ventral T11-12 CSF leak underwent endoscopic repair.

Neurosurg FocusOct 1, 2026Read case
Clinical ResearchEndocrinologyOpen access

Reporting Gaps in mHealth Intervention Studies for Adults With Diabetes: Systematic Review.

This systematic review evaluated the reporting completeness of 144 randomized controlled trials (RCTs) on mHealth interventions for adults with diabetes using the mERA checklist.

JMIR Mhealth UhealthOct 1, 2026Read summary
Clinical ResearchPediatricsOpen access

Efficacy of nebulized salbutamol in transient tachypnea of the newborn: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy of nebulized salbutamol in improving clinical outcomes for infants with transient tachypnea of the newborn (TTN).

PLoS OneOct 1, 2026Read summary
Case ReportNephrology

Resistant Hypertension Secondary to Renal Arteriovenous Malformation: A Case of Cure After Nephrectomy.

A 33-year-old woman with longstanding uncontrolled hypertension requiring five antihypertensive agents was evaluated for refractory blood pressure control.

Am J Case RepOct 1, 2026Read case
Clinical ResearchPsychiatry

Negative affect influences the computations underlying food choice in bulimia nervosa.

This randomized controlled trial examined how negative affect influences food choice dynamics in 25 women with bulimia nervosa (BN) and 21 healthy controls.

ElifeOct 1, 2026Read summary
Clinical ResearchUrologyOpen access

Remote robotic urological surgery with the Toumai® System across 25-7,000 km: a systematic review and single-arm meta-analysis of technical success and reported safety.

To summarize the early clinical experience with the Toumai ® robotic system in remote urological surgery and to descriptively synthesize technical success, perioperative outcomes, and network performance, while…

J Robot SurgOct 1, 2026Read summary
Clinical ResearchPsychiatryOpen access

Neural correlates of acute task-related stress in humans: a systematic review and coordinate-based ALE meta-analysis.

This systematic review and ALE meta-analysis examined the neural correlates of acute task-related stress using task-based fMRI studies.

Brain Imaging BehavOct 1, 2026Read summary
Case ReportNephrologyOpen access

Resolution of restless legs syndrome after postdilution online hemodiafiltration using a vitamin E-bonded polysulfone membrane: a report of two cases.

Two patients with long-standing, refractory restless legs syndrome underwent high-efficiency online hemodiafiltration but did not achieve sufficient symptom relief.

J Artif OrgansOct 1, 2026Read case
Clinical ResearchNeurologyOpen access

MicroRNAs Regulation of Axon Sprouting in Peripheral Nerve Regeneration: A Systematic Review.

This systematic review examines the role of microRNAs (miRNAs) in peripheral nerve regeneration, focusing on miR-21, miR-133b, miR-124, and miR-30b.

Mol NeurobiolOct 1, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Network meta-analysis of robotic ventral and incisional hernia repair techniques: intraperitoneal, preperitoneal, retromuscular, and sublay approaches.

This network meta-analysis evaluated the efficacy and safety of various robotic ventral and incisional hernia repair techniques in 9,348 adults.

HerniaOct 1, 2026Read summary
Clinical ResearchEndocrinologyOpen access

The role of vitamin D signalling in β cell apoptosis: a systematic review.

This systematic review examined the role of vitamin D signalling in pancreatic β-cell apoptosis, analyzing 26 studies across various models.

ApoptosisOct 1, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Cellular, Acellular, and Matrix-Like Placental Products for Diabetic Foot Ulcers: A 12-Week Randomised-Trial Meta-Analysis.

This meta-analysis evaluated the effectiveness of placental-derived cellular, acellular, and matrix-like products (CAMPs) as adjuncts to standard care for diabetic foot ulcers (DFUs) in adults.

Int Wound JOct 1, 2026Read summary
Clinical ResearchPsychiatry

Age- and sex-specific trends in Canadian mental health from 2003 to 2024: a repeated cross-sectional meta-regression analysis.

This meta-analysis examined trends in mental health outcomes in Canada from 2003 to 2024, using data from the Canadian Community Health Survey.

Epidemiol Psychiatr SciOct 1, 2026Read summary
Clinical ResearchDermatologyOpen access

New Primary and Secondary Prevention Measures for Cutaneous Melanoma: A Systematic Review.

This systematic review evaluated recent evidence on primary and secondary prevention strategies for cutaneous melanoma, analyzing 24 studies.

Cancer Rep (Hoboken)Oct 1, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Neuro-linguistic programming for postoperative pain management: A randomized controlled trial.

This randomized controlled trial evaluated the impact of a single neuro-linguistic programming (NLP) session on postoperative pain management in 76 women after cesarean delivery.

Afr J Reprod HealthOct 1, 2026Read summary
Clinical ResearchHematologyOpen access

Low-Dose Cytarabine Plus G-CSF Induction in Pediatric M2 Acute Myeloid Leukemia: A Multicenter Study.

This multicenter randomized controlled trial analyzed the efficacy and safety of low-dose chemotherapy (LDC) versus standard-dose chemotherapy (SDC) in 221 children with M2 acute myeloid leukemia.

Cancer MedOct 1, 2026Read summary
Case ReportCardiology

Apheresis-Triggered Torsades De Pointes in Congenital Long QT Syndrome Type 2: Citrate-Related Arrhythmia Risk and Safe Modality Switching During Myasthenic Crisis.

A 44-year-old woman with congenital long QT syndrome Type 2 presented in myasthenic crisis due to anti-MuSK-positive myasthenia gravis.

J Clin ApherOct 1, 2026Read case
Clinical ResearchGeneral Surgery

LigaSure versus conventional excisional haemorrhoidectomy: A systematic review and meta-analysis with trial sequential analysis of randomised controlled trials.

This systematic review and meta-analysis evaluated 43 randomized controlled trials involving 3,277 participants to compare LigaSure with conventional excisional haemorrhoidectomy.

Colorectal DisOct 1, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Carbon nanoparticle-Fe (II) complex for ferroptosis therapy in refractory solid tumors: a phase I trial.

This phase I trial evaluated the safety and preliminary efficacy of a carbon nanoparticle-Fe (II) complex (CNSI-Fe) in 19 patients with refractory solid tumors.

Signal Transduct Target TherOct 1, 2026Read summary

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