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1566 articles

September 202624

Case ReportNephrologyOpen access

When two rare diseases meet: atypical hemolytic uremic syndrome and alkaptonuria in two siblings.

Two brothers from a consanguineous family presented with recurrent episodes of atypical hemolytic uremic syndrome (aHUS) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury.

CEN Case RepSep 30, 2026Read case
Case ReportNephrologyOpen access

FAT1-associated membranous nephropathy after hematopoietic stem cell transplantation: a case report and review of the literature.

A 55-year-old man developed nephrotic syndrome 52 months post-allogeneic hematopoietic stem cell transplantation for acute lymphoblastic leukemia.

CEN Case RepSep 30, 2026Read case
Clinical ResearchGastroenterologyOpen access

16S rRNA Datasets of Gut Microbiota in Stent-Based Diverting Technique and Ileostomy from A Prospective, Open-Label, Multicenter Randomized Controlled Trial.

This study presents a 16S rRNA amplicon dataset from a multicenter randomized controlled trial involving 80 patients undergoing either a stent-based diverting technique (SDT) or ileostomy after rectal cancer surgery.

Sci DataSep 30, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Safety and efficacy of human gingiva-derived mesenchymal stem cells in patients with type 1 diabetes: a double-blind, randomized, placebo-controlled, phase 1 trial.

This phase 1 double-blind, randomized, placebo-controlled trial evaluated the safety and efficacy of human gingiva-derived mesenchymal stem cells (GMSCs) in 18 patients with type 1 diabetes mellitus (T1DM).

Signal Transduct Target TherSep 30, 2026Read summary
Clinical ResearchOncology (Medical)

Coffee consumption and head and neck cancer risk: a dose-response and site-specific meta-analysis.

This meta-analysis examined the relationship between coffee consumption and head and neck cancer (HNC) risk across 30 studies.

Eur J Cancer PrevSep 30, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Effect of early regional anesthesia on postoperative cognitive function and the perioperative stress response in patients with hip fractures: a randomized controlled trial.

This randomized controlled trial investigated the effect of anterior iliopsoas muscle space block (AIMSB) timing on postoperative delirium (POD) in 79 elderly patients undergoing total hip arthroplasty for fractures.

PeerJSep 30, 2026Read summary
Clinical ResearchGastroenterology

Efficacy and safety of tegoprazan-amoxicillin dual therapy versus bismuth-containing quadruple therapy for first-line Helicobacter pylori eradication: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the efficacy and safety of 14-day tegoprazan-amoxicillin dual therapy versus bismuth-containing quadruple therapy (BQT) for first-line Helicobacter pylori eradication…

Eur J Gastroenterol HepatolSep 30, 2026Read summary
Clinical ResearchGastroenterology

A meta-analysis of transjugular intrahepatic portosystemic shunt with or without embolization for esophageal and gastric variceal bleeding in decompensated liver cirrhosis.

This meta-analysis evaluated the efficacy of transjugular intrahepatic portosystemic shunt (TIPS) with or without embolization in 3079 patients with decompensated liver cirrhosis experiencing esophageal and gastric…

Eur J Gastroenterol HepatolSep 30, 2026Read summary
Clinical ResearchGastroenterology

Percutaneous catheter drainage versus needle aspiration for liver abscess: a systematic review and meta-analysis of efficacy and safety.

This systematic review and meta-analysis evaluated the efficacy and safety of percutaneous catheter drainage (PCD) versus needle aspiration (PNA) for liver abscesses in 1425 adults.

Eur J Gastroenterol HepatolSep 30, 2026Read summary
Clinical ResearchGastroenterology

Efficacy of pancreatic enzyme replacement therapy on exocrine pancreatic insufficiency: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy of pancreatic enzyme replacement therapy (PERT) in improving nutrient absorption in patients with exocrine pancreatic insufficiency (EPI).

Eur J Gastroenterol HepatolSep 30, 2026Read summary
Case ReportOtolaryngology (ENT)Open access

Pyogenic Granuloma in the Sinonasal Cavity: A Potential 38-Year Latency Following Foreign Body Entrapment.

A 43-year-old male presented with left-sided nasal obstruction, rhinorrhea, and hyposmia for two months. Endoscopic evaluation and imaging revealed a highly vascular mass on the left middle turbinate.

Int Med Case Rep JSep 30, 2026Read case
Case ReportAnesthesiologyOpen access

Dexketoprofen Trometamol Plus Sufentanil for Analgesia After Thoracoscopic Radical Resection of Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial.

Evidence for adding dexketoprofen trometamol to sufentanil-based patient-controlled intravenous analgesia (PCIA) after thoracoscopic radical resection of lung cancer remains limited.

Drug Des Devel TherSep 30, 2026Read case
Case ReportAnesthesiologyOpen access

Tegileridine versus Sufentanil for Patient-Controlled Intravenous Analgesia After Cesarean Delivery: A Randomized Double-Blind Trial.

Postoperative nausea and vomiting (PONV) remains one of the most common opioid-related adverse events after cesarean delivery despite multimodal analgesia.

Drug Des Devel TherSep 30, 2026Read case
Case ReportPediatricsOpen access

Thalamic Tuberculoma Presenting as Isolated Gait Disturbance Without Systemic or Meningeal Symptoms in a 2-Year-Old Child: A Case Report.

A 2-year-old boy presented with isolated gait disturbance and decreased power on the left side, without systemic or meningeal symptoms.

Int Med Case Rep JSep 30, 2026Read case
Clinical ResearchPulmonologyOpen access

A specialist-led interprofessional weaning program to prevent weaning failure in high-risk patients: the PRiVENT study.

The PRiVENT study evaluated a specialist-led interprofessional weaning program for high-risk mechanically ventilated patients in a multicenter, non-randomized trial.

Crit CareSep 30, 2026Read summary
Clinical ResearchPediatrics

The association between disability and mortality among children and adolescents: A systematic review and meta-analysis.

This systematic review and meta-analysis examined all-cause mortality among children and adolescents with disabilities compared to non-disabled peers, analyzing 29 studies with over 35 million participants.

PLoS MedSep 30, 2026Read summary
Clinical ResearchDermatology

Implementation of Total Body Photography for Skin Cancer Early Detection: A Systematic Review.

This systematic review examined how total body photography (TBP) has been implemented and used for skin cancer detection and surveillance across healthcare settings.

Int J DermatolSep 30, 2026Read summary
Clinical ResearchPediatrics

Does a Simple Touch Make a Difference? The Effect of Acupressure on Pain Scores in Infants Undergoing Cardiac Catheterization: A Randomized, Placebo-Controlled Trial.

This randomized, placebo-controlled trial evaluated acupressure in 60 infants aged 1–12 months with congenital heart disease undergoing cardiac catheterization.

J Cardiovasc NursSep 30, 2026Read summary
Clinical ResearchPsychiatry

Sex differences in the efficacy, acceptability, and tolerability of antipsychotics in people with acute schizophrenia: individual participant data pairwise, dose-response, and network meta-analyses.

This individual participant data pairwise, dose-response, and network meta-analysis examined sex differences in antipsychotic efficacy, acceptability, and tolerability in adults with acute schizophrenia.

Lancet PsychiatrySep 30, 2026Read summary
Clinical ResearchNeurosurgery

More than meets the eye: A meta-analysis of visual outcomes following clipping, coiling, and flow diversion for visually symptomatic paraclinoid aneurysms.

This PRISMA-compliant systematic review and random-effects meta-analysis compared visual outcomes after clipping, coiling, and flow diversion for paraclinoid aneurysms, drawing on 21 studies.

J Clin NeurosciSep 30, 2026Read summary
Clinical ResearchGastroenterology

8 weeks versus 12 weeks of sofosbuvir-velpatasvir for treatment-naive, non-cirrhotic, chronic hepatitis C (RESOLVE): a multicentre, open-label, non-inferiority, randomised controlled trial in India.

The RESOLVE multicentre, open-label, randomised non-inferiority trial compared 8 versus 12 weeks of daily sofosbuvir-velpatasvir in treatment-naive adults with chronic hepatitis C without cirrhosis at five publicly…

LancetSep 30, 2026Read summary
Clinical ResearchCardiology

Cardiovascular safety of orforglipron versus insulin glargine in adults with type 2 diabetes at increased cardiovascular risk (ACHIEVE-4): a phase 3, event-driven, randomised, open-label, non-inferiority, active comparator trial.

ACHIEVE-4 was a phase 3, event-driven, multicentre, randomised, open-label, active-comparator non-inferiority trial comparing once-daily oral orforglipron with titrated insulin glargine in adults with type 2 diabetes…

LancetSep 30, 2026Read summary
Clinical ResearchGastroenterology

Prognostic Models for Predicting the Severity and Mortality in People With Acute Pancreatitis - A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed how accurately four clinical scoring systems predict severe acute pancreatitis (SAP) and mortality in adults.

J Surg ResSep 30, 2026Read summary
Case ReportNeurology

Neurosyphilis Concurrently Presenting With Limbic Encephalitis and Normal Pressure Hydrocephalus: A Case Report.

A 47-year-old man presented with cognitive decline, gait disturbance, and urinary incontinence. Imaging revealed ventricular enlargement and high signal intensity in the medial temporal lobes.

Neuropsychopharmacol RepSep 29, 2026Read case

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