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1696 articles

September 202616

Clinical ResearchOncology (Medical)

Systemic and intracranial activity of antibody-drug conjugates in patients with non-small cell lung cancer and brain metastases: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed systemic and intracranial responses to antibody-drug conjugates (ADCs) in patients with non-small cell lung cancer and brain metastases.

Lung CancerSep 28, 2026Read summary
Clinical ResearchNeurology

Association between insular involvement and ECG abnormalities in ischemic stroke: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether insular involvement in ischemic stroke is associated with ECG abnormalities, using cohort and cross-sectional studies comparing patients with and without insular…

J Clin NeurosciSep 28, 2026Read summary
Clinical ResearchMedical Genetics

Efficacy and safety of garetosmab, an activin A-blocking antibody, in fibrodysplasia ossificans progressiva (OPTIMA): a randomised, double-blind, placebo-controlled, phase 3 trial.

OPTIMA was a multicentre, randomised, double-blind, placebo-controlled phase 3 trial assessing monthly intravenous garetosmab in adults with fibrodysplasia ossificans progressiva.

LancetSep 28, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Non-usage rates after paediatric cochlear implantation: A systematic review and meta-analysis.

This systematic review and meta-analysis examined long-term cochlear implant use among paediatric recipients, synthesising 29 studies involving 2,595 children.

Int J Pediatr OtorhinolaryngolSep 28, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

The effect of acute pain on proprioceptive performance: A systematic review and meta-analysis.

This systematic review and meta-analysis examined whether acute pain is associated with changes in behavioural proprioception measures.

J PainSep 28, 2026Read summary
Clinical ResearchNeurology

Prevalence of autoimmune comorbidities in aquaporin 4-immunoglobulin G positive neuromyelitis optica spectrum disorder: a systematic review and meta-analysis.

This systematic review and meta-analysis estimated the prevalence of autoimmune comorbidities among people with aquaporin-4-immunoglobulin G-positive neuromyelitis optica spectrum disorder.

Mult Scler Relat DisordSep 28, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Current Evidence on Periprocedural Flat-Panel CT in Endovascular Stroke Treatment: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined periprocedural flat-panel CT (FPCT) findings and clinical applications in patients undergoing endovascular stroke treatment.

StrokeSep 28, 2026Read summary
Case ReportCardiology

The "Spiked Helmet Sign" on Electrocardiogram Following Left Ventricular Assist Device Implantation: A Case Report.

A 68-year-old male with end-stage ischemic cardiomyopathy underwent left ventricular assist device (LVAD) implantation. Shortly after the procedure, his ECG displayed the 'Spiked Helmet Sign' alongside QTc prolongation.

Ann Noninvasive ElectrocardiolSep 27, 2026Read case
Clinical ResearchOncology (Medical)

External validation of the NADIR model for early prostate-specific antigen response prediction in enzalutamide-treated metastatic hormone-sensitive prostate cancer: An analysis of the ARCHES trial.

This validation study assessed the NADIR model's ability to predict early prostate-specific antigen (PSA) response in 558 enzalutamide-treated patients from the ARCHES trial.

CancerSep 27, 2026Read summary
Clinical ResearchNephrologyOpen access

Longitudinal impact of sodium bicarbonate therapy on health-related quality of life in pre-dialysis chronic kidney disease with metabolic acidosis: a pragmatic trial in Malaysia.

This pragmatic clinical trial evaluated the impact of sodium bicarbonate therapy on health-related quality of life (HRQoL) in 74 pre-dialysis chronic kidney disease (CKD) patients with metabolic acidosis over 18 months.

Qual Life ResSep 27, 2026Read summary
Case ReportMedical GeneticsOpen access

Phenotypic spectrum of 19p13.3 microdeletion: a fatal infant case with severe cardiomegaly and gastrointestinal manifestations.

An 8-month-old female infant presented with multisystemic complications, including congenital heart defects, limb anomalies, macrocephaly, and recurrent pulmonary infections.

Mol Biol RepSep 27, 2026Read case
Case ReportInfectious Diseases

Pulmonary Actinomycosis Diagnosed via BALF mNGS in a 53-Year-Old Nonsmoking Man With Pneumoconiosis and Penicillin-Induced Thrombocytopenia: A Case Report.

A 53-year-old nonsmoking man with pneumoconiosis presented with a month-long history of cough and hemoptysis. Imaging revealed bilateral upper-lung masses and lymphadenopathy, leading to a right upper lobectomy under…

Am J Case RepSep 27, 2026Read case
Clinical ResearchObstetrics & Gynecology

Determinants of preterm pre-eclampsia following low-dose aspirin prophylaxis: evidence from stepped-wedge cluster randomized trial in Asia.

This multicenter stepped-wedge cluster randomized trial studied 2919 high-risk pregnant women receiving low-dose aspirin prophylaxis to identify risk factors for preterm pre-eclampsia (PE).

Ultrasound Obstet GynecolSep 27, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Low-intensity pulsed ultrasound to facilitate uterine involution: prospective multicenter study on clinical efficacy and mechanistic insights.

This multicenter, randomized controlled trial evaluated the efficacy of low-intensity pulsed ultrasound (LIPUS) in promoting uterine involution post-delivery among 1,106 women.

Ultrasound Obstet GynecolSep 27, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Mindful eating as a supportive intervention for breast cancer survivors: a pilot randomized controlled trial.

This pilot randomized controlled trial assessed whether a six-session mindful eating intervention added to treatment-as-usual (TAU) improved eating behaviors and body composition in breast cancer survivors.

Breast CancerSep 27, 2026Read summary
Clinical ResearchCardiology

Cost-effectiveness of heart failure pharmacotherapy withdrawal in recovered atrial fibrillation mediated cardiomyopathy: analysis of the WITHDRAW-AF randomized clinical trial.

This economic analysis of the WITHDRAW-AF randomized clinical trial compared heart failure pharmacotherapy withdrawal with continuation in carefully selected patients with recovered atrial fibrillation-mediated…

Int J CardiolSep 27, 2026Read summary

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