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1688 articles
October 202624
Myeloid neoplasm with PDGFRA rearrangement presenting in blast-phase with basophilia.
An adult man from Southern Africa presented with progressive fatigue. Blood morphology showed marked basophilia and 21% myeloblasts, with flow cytometry supporting a provisional diagnosis of acute myeloid leukaemia with…
Application of a concise video to improve patient understanding of tumor genomic testing in community and academic practice settings.
This multicenter clinical trial evaluated a 3–4 minute educational video for patients undergoing standard-of-care tumor genomic testing (TGT), across cancer types and academic and community settings.
Factors associated with 1-year health-related quality of life after neck-specific exercise in chronic whiplash-associated disorders: an exploratory secondary analysis of a randomized controlled trial.
This exploratory secondary analysis of a prospective, assessor-blinded, multicentre randomised trial examined factors associated with health-related quality of life (HRQoL) after neck-specific exercise in 140 people…
Extensive recurrent pterygium following photorefractive keratectomy: a case report.
A healthy 39-year-old man developed an extensive recurrent pterygium three months after uneventful photorefractive keratectomy (PRK), having undergone primary pterygium surgery two months before PRK.
Safety and immunogenicity of Thailand Government Pharmaceutical Organization (GPO) produced, COVID-19 vaccine, 10 μg HXP-GPOVac: A Phase III, double-blind, randomized trial in comparison with VAXZEVRIA.
This phase III, double-blind, randomized active-controlled trial compared a single dose of Thailand-produced HXP-GPOVac with VAXZEVRIA in healthy or clinically stable Thai adults who had completed a two-dose COVID-19…
Effect of diet-induced plasma ceramide on human in vivo microvascular endothelial function.
This double-blind, randomized crossover trial examined whether a meal-induced rise in plasma ceramides impairs in vivo microvascular function in 23 healthy young adults.
Epigenetic insights into anti-tuberculosis drug-induced liver injury: A systematic review of DNA methylation as a potential biomarker.
This systematic review assessed whether DNA methylation patterns are associated with susceptibility to anti-tuberculosis drug-induced liver injury (ATDILI).
Bee Sting-Associated Kounis Syndrome Presenting as Myocardial Infarction: A Case Report and Systematic Review with Age-Based Analysis.
A 44-year-old man presented with myocardial infarction after a probable bee sting-associated allergic reaction and was considered to have Kounis syndrome, an acute coronary syndrome linked to hypersensitivity.
Comparative efficacy of topical garlic extract and 20% podophyllin solution in the treatment of female genital warts: a triple-blind randomized clinical trial.
This triple-blind randomized clinical trial compared topical 5% garlic extract with 20% podophyllin in 74 women with genital warts, applied weekly for four weeks.
Impact of Extent of Coronary Artery Disease in Transcatheter Aortic Valve Replacement: A PRO-TAVI Substudy.
This post hoc substudy of the multicentre randomised PRO-TAVI trial examined whether coronary disease complexity, measured by SYNTAX score, was associated with outcomes among 466 patients with significant coronary…
Immediate Versus Staged Complete Revascularization in Multivessel Disease and STEMI: A Meta-Analysis of Randomized Trials.
This frequentist meta-analysis of four multicentre randomised trials compared immediate with staged complete revascularization in 2,651 patients with STEMI and multivessel disease.
Occlusion-Focused Triage vs Very-High-Risk NSTEMI Criteria: A DIFOCCULT-3 Substudy.
This substudy of the multicenter, cluster-randomized DIFOCCULT-3 trial compared occlusion/nonocclusion (OMI/NOMI) classification with the conventional STEMI/NSTEMI framework and guideline-defined very-high-risk NSTEMI…
Predictors of immunological non-response despite virological suppression in people living with HIV on antiretroviral therapy: A systematic review and meta-analysis.
This systematic review and meta-analysis examined clinical, demographic and molecular predictors of inadequate CD4+ T-cell recovery despite viral suppression on antiretroviral therapy in people living with HIV.
Effectiveness of a self-management intervention on clinical outcomes among patients with type 2 diabetes at high risk for Diabetic Kidney Disease: A Randomised Controlled Trial.
This prospective, two-arm randomised controlled trial at a tertiary hospital in China evaluated a structured self-management programme in 134 adults with type 2 diabetes classified as at high risk of diabetic kidney…
Menstrual health challenges and associated barriers among tribal adolescent girls in India: A systematic review.
This systematic review synthesised quantitative, qualitative and mixed-methods research on menstrual health among tribal adolescent girls in India.
Hodgkin Lymphoma With Sarcoid-Like Reaction: Importance of Clinicopathological Correlation in Granulomatous Lymphadenopathy.
A 63-year-old man with systemic lymphadenopathy had a cervical lymph node biopsy showing epithelioid granulomas but no identifiable neoplastic cells, prompting an initial suspicion of sarcoidosis.
Early-onset autosomal dominant distal renal tubular acidosis caused by a de novo SLC4A1 R589C variant with growth failure and rickets.
A Japanese boy had marked growth failure from 6 months of age and was diagnosed with autosomal dominant distal renal tubular acidosis at 27 months.
A case of immunofluorescence-negative light chain deposition disease diagnosed by mass spectrometry.
A 53-year-old man with kidney dysfunction and edema had nodular glomerular lesions on biopsy, but immunofluorescence did not show immunoglobulin or light-chain deposits.
Postoperative acute kidney injury associated with cast nephropathy and marked renal interstitial plasma cell infiltration in multiple myeloma: a case report.
An 84-year-old man with smoldering multiple myeloma developed severe acute kidney injury after lumbar fixation for a burst fracture.
Delayed eculizumab therapy guided by markedly elevated soluble C5b-9 in a child with dialysis-requiring acute poststreptococcal glomerulonephritis: a case report.
A 9-year-old girl developed gross haematuria, oliguria and stage 3 acute kidney injury after an illness with vomiting and abdominal pain.
Next-generation pharmacological strategies for Parkinson's disease: a systematic literature review of symptom management and disease modification.
This PRISMA 2020 systematic literature review assessed pharmacological and emerging therapeutic strategies for symptom management and disease modification in Parkinson disease.
Resilience interventions for stress-related health outcomes in patients with cancer: Findings from a systematic review of randomized controlled trials.
This systematic review synthesized randomized controlled trials of resilience interventions for stress-related health outcomes in patients with cancer.
Anatomical variation in the cervical branch of the facial nerve: a systematic review.
There is a paucity of literature on the anatomical variations of the cervical branch of the facial nerve (CBFN). Poor awareness of its anatomy and variations risks intraoperative damage, misdiagnosis of facial nerve…
Laparoscopic and robotic management of symptomatic calyceal diverticula: a systematic review on behalf of YAU and EAU endourology.
This systematic review assessed laparoscopic and robot-assisted management of symptomatic calyceal diverticula. Nine studies were included in a qualitative synthesis.
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