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1688 articles
October 202624
Dynamics and functional heterogeneity of FOXP3+ regulatory T cells in Trypanosoma cruzi infection: a systematic review.
This systematic review synthesised 27 studies of FOXP3+ regulatory T-cell (Treg) phenotype and function in human and experimental Trypanosoma cruzi infection: 9 human studies and 18 murine studies.
A case of renal hypouricemia type 1 associated with compound heterozygous URAT1/SLC22A12 variants A209V and F379L: clinical evidence for their pathogenic significance.
A 69-year-old woman was evaluated for renal dysfunction and hypouricemia. Testing showed serum uric acid of 0.7 mg/dL and a fractional urate clearance (Cua/Ccr) of 60.5%, alongside CKD stage G3b and a renal stone.
Continuous intrathecal therapy for refractory cancer pain: A systematic review and meta-analysis focusing on partially implanted devices.
This systematic review and meta-analysis assessed partially implanted intrathecal devices (PIDs) for adults with refractory cancer-related pain, comparing them with conventional medical management and, in comparative…
Blood pressure targets in adults with hypertension.
This publication is a protocol for a Cochrane intervention review, not a report of completed results. It sets out to assess lower blood pressure targets (≤ 135/85 mmHg) versus standard targets (≤ 140 to 160/90 to 100…
Home visits following hospital discharge for families with preterm and low-birthweight infants.
This Cochrane systematic review and meta-analysis assessed randomised trials of home visits after discharge for families of preterm or low-birthweight infants.
Extracting the Unexpected: A 35-mm Curved Nail as an Intraocular Foreign Body.
A 31-year-old man presented with left-eye pain and severe vision loss seven days after penetrating injury from a metallic object.
Effect of injectable platelet rich fibrin augmented with vitamin c compared to injectable platelet rich fibrin alone on healing of necrotic mature single rooted teeth with chronic periapical periodontitis following regenerative endodontic therapy (a randomized controlled trial).
This randomized controlled trial compared injectable platelet-rich fibrin (i-PRF) with and without vitamin C during regenerative endodontic treatment in 28 healthy patients with necrotic mature single-rooted teeth and…
Comparative perioperative outcomes of Hugo™ RAS versus laparoscopic and Da Vinci platforms for partial nephrectomy: a systematic review and meta-analysis.
This systematic review and meta-analysis compared Hugo™ RAS with da Vinci-assisted and laparoscopic partial nephrectomy. It included four observational cohort studies comprising 383 patients.
Robot-assisted ileal ureter replacement for complex ureteral strictures: a systematic review and single-arm meta-analysis of surgical and functional outcomes.
This systematic review and single-arm meta-analysis assessed surgical and functional outcomes after robot-assisted ileal ureter replacement (RIUR) in adults with complex ureteral strictures.
Stereotactic body radiotherapy versus conventional external beam radiotherapy for bone metastases: a meta-analysis.
This systematic review and meta-analysis compared stereotactic body radiotherapy (SBRT) with conventional external beam radiotherapy (cEBRT) for painful bone metastases, pooling comparative clinical studies using…
Predicting IGD treatment outcomes across interventions using a whole-brain functional connectome biomarker.
This clinical trial study examined whether resting-state whole-brain functional connectivity could predict symptom improvement in 90 individuals with internet gaming disorder (IGD) receiving mindfulness meditation…
Robotic Parenchyma-Preserving Pancreatic Resection for Focal Congenital Hyperinsulinism in an Infant.
An infant weighing 4.6 kg with focal congenital hyperinsulinism underwent robot-assisted, parenchyma-preserving pancreatic resection using indocyanine green, intraoperative ultrasound, and suture-based retraction.
Robotic-assisted versus conventional coronary artery bypass grafting: a systematic review, meta-analysis, and trial sequential analysis of 39,918 patients.
This systematic review and meta-analysis compared robotic-assisted with conventional coronary artery bypass grafting (CABG) across nine observational studies involving 39,918 patients.
Improvement in peripheral airway function after a 12-week exercise intervention in COPD.
This prospective, multicenter, single-arm non-randomized intervention study assessed lung function, exercise capacity and symptoms before and after a 12-week supervised exercise program in 62 people with COPD.
The effectiveness of guided botulinum toxin "A" injection to the masticatory muscles in the management of condylar and sub condylar fractures: a randomized controlled clinical trial.
This randomized controlled clinical trial compared ultrasound-guided botulinum toxin A injections into the masseter, temporalis and lateral pterygoid muscles plus closed reduction with closed reduction alone in 16…
Analgesic efficacy of uni-level erector spinae plane block in breast cancer surgery patients: a systematic review and Meta-analysis.
This systematic review and meta-analysis assessed uni-level erector spinae plane block (ESPB) as an adjunct to general anesthesia and opioids for breast cancer surgery.
Oral eplerenone in first-episode acute central serous chorioretinopathy: results of a double-masked randomized trial.
This double-masked, randomized, placebo-controlled trial evaluated oral eplerenone in 44 patients with first-episode acute central serous chorioretinopathy (CSCR).
Sustained potassium control and recurrent hyperkalemia during individualized potassium-guided sodium zirconium cyclosilicate titration in maintenance hemodialysis: a post hoc analysis of a randomized trial.
This exploratory post hoc analysis of a single-centre, open-label randomised trial assessed sustained potassium control with individualized potassium-guided sodium zirconium cyclosilicate (SZC) in 116 maintenance…
Progestogens, cervical cerclage, and cervical pessary for preventing preterm birth in asymptomatic singleton pregnancies with a sonographic short cervix and no previous history of spontaneous preterm birth: systematic review and bayesian network meta-analysis.
This systematic review and Bayesian network meta-analysis compared interventions to prevent preterm birth in asymptomatic women with singleton pregnancies, a sonographic short cervix, and no previous spontaneous preterm…
The Effects of Multimodal Communication Treatment With Discourse and Group Activities via Telepractice on People With Severe Nonfluent Aphasia: A Case Study.
Two people with severe nonfluent aphasia—one with Broca’s aphasia and one with global aphasia—received 10 weeks of telepractice multimodal communication treatment.
Use of Instructional Therapeutic Play during the preoperative nursing consultation of a child with orofacial clefts.
An 8-year-old girl with an orofacial cleft was preparing for cleft palate repair and expressed fear and anxiety about surgery, especially that she might not wake up after anesthesia.
Osteopathic manual therapy in fibromyalgia: a pilot study.
This pilot randomised controlled trial assessed whether adding osteopathic manual therapy to Clinical Pilates improved pain, symptom severity, pressure pain threshold, and sleep in 20 women with fibromyalgia.
Effectiveness of a fully digital mandibular advancement appliance compared with CPAP in the treatment of obstructive sleep apnea.
This crossover clinical study compared a fully digital mandibular advancement appliance (MAA) with CPAP in 20 adults with obstructive sleep apnea (OSA), confirmed by polysomnography and non-adherent to CPAP.
Brought with the wind: A case of melioidosis acquired in the United States presenting with multiple pulmonary nodules.
A Florida resident without recent international travel presented with fever, pleuritic chest pain, and hypoxia after severe weather.
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