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1616 articles

October 202624

Case ReportMedical Genetics

Beyond Hereditary Haemorrhagic Telangiectasia (HHT): Capillary Malformation-Arteriovenous Syndrome (CM-AVM).

An asymptomatic woman in her forties was referred for suspected hereditary haemorrhagic telangiectasia (HHT) after mucocutaneous telangiectasia was noted on her face, lips and hands.

Ir Med JOct 22, 2026Read case
Case ReportEmergency Medicine

Pulmonary embolism mimicking myocardial ischemia in an Emergency Department.

A man in his seventies presented to the emergency department with sudden central chest pain radiating to both arms and diaphoresis, raising concern for myocardial ischemia.

Ir Med JOct 22, 2026Read case
Case ReportInfectious Diseases

Simple Site, Serious Sequelae: Septic Emboli from a Peripheral Cannula.

A young woman developed right arm pain and pleuritic chest pain after a recent hospitalisation, with marked inflammation (CRP 296 mg/L, WCC 13.7 ×10⁹/L).

Ir Med JOct 22, 2026Read case
Case ReportRheumatologyOpen access

Avoiding Diagnostic Overshadowing: A Case Series on Cervical Myelopathy in Patients with Fibromyalgia.

Three patients referred to a multidisciplinary chronic pain clinic for fibromyalgia evaluation had substantial physical and neurological impairment.

Int Med Case Rep JOct 22, 2026Read case
Case ReportObstetrics & Gynecology

A Cluster of Anencephaly Cases: The Potential Preventative Role of Folic Acid Fortification.

Over two weeks, a peripheral maternity unit identified four fetuses with severely abnormal cranial views on ultrasound; three cases were described.

Ir Med JOct 22, 2026Read case
Case ReportNeurosurgeryOpen access

Unexpected Right-Sided Nerve Root Variant During L4-L5 Microdiscectomy and Decompression: A Case Report Highlighting Diagnostic and Intraoperative Challenges.

A 45-year-old woman presented with predominantly right-sided leg numbness and paresthesia, radiating pain, and preserved strength.

Int Med Case Rep JOct 22, 2026Read case
Clinical ResearchOrthopedic SurgeryOpen access

Mid-term clinical outcomes and isokinetic performance after primary total knee arthroplasty within a modified ERAS protocol: a single-blinded randomized controlled trial.

This prospective, single-blinded randomized controlled trial compared a modified Enhanced Recovery After Surgery (ERAS) protocol with conventional perioperative care in 58 patients undergoing primary total knee…

BMC Musculoskelet DisordOct 22, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Outcomes of Mindful Mood Balance for Moms, online mindfulness-based cognitive therapy for perinatal depressive relapse prevention in the USA: a two-arm, single-blind, pragmatic randomised clinical trial.

This single-blind, pragmatic randomised clinical trial tested a web-based mindfulness-based cognitive therapy programme plus usual care against usual care alone in euthymic pregnant women with recurrent depression and…

Lancet Public HealthOct 21, 2026Read summary
Clinical ResearchEmergency Medicine

A multifaceted intervention to increase bystander CPR rates after out-of-hospital cardiac arrest in France: a stepped-wedge, cluster-randomised, controlled trial.

This stepped-wedge, cluster-randomised controlled trial assessed a coordinated intervention to increase bystander CPR before EMS arrival among adults with non-traumatic out-of-hospital cardiac arrest in France.

Lancet Public HealthOct 21, 2026Read summary
Case ReportCardiology

Spiked Helmet Sign in the Early Post-Heart Transplantation Period: A Dramatic STEMI Mimic in a Structurally Normal Donor Heart.

A 36-year-old woman with severe dilated cardiomyopathy underwent heart transplantation and subsequently developed subarachnoid hemorrhage and septic shock.

Ann Noninvasive ElectrocardiolOct 21, 2026Read case
Clinical ResearchGastroenterology

Effects of Aerobic Exercise on Autonomic and Endothelial Function and Splanchnic Hemodynamics in Compensated Cirrhosis: RCT Study.

This parallel-group randomised controlled trial assessed 16 weeks of moderate-intensity aerobic exercise plus nutritional consultation versus nutritional consultation alone in 50 sedentary patients with compensated…

Liver IntOct 21, 2026Read summary
Clinical ResearchEndocrinology

Excess Liver Fat in Type 2 Diabetes Stratified by Intrapancreatic Fat Deposition: A Meta-Analysis of Dual-Organ MRI Studies.

This meta-analysis pooled dual-organ MRI studies comparing liver fat content (LFC) in people with type 2 diabetes (T2DM) and non-diabetic controls, and examined whether study-level intrapancreatic fat deposition (IPFD)…

Liver IntOct 21, 2026Read summary
Clinical ResearchEndocrinology

From Alert to Action: Electronic Practice Advisory Improves DSMES Referrals Over 18 Months.

This cluster-randomized controlled trial in primary care practices in central North Carolina tested whether an electronic health record best practice advisory (BPA) increased referrals to diabetes self-management…

Diabetes CareOct 21, 2026Read summary
Clinical ResearchRheumatology

Calorie-Restricted DASH, Carbohydrate-Restricted, and Low-Purine Diets for Weight Loss and Urate Control in Men With Overweight or Obesity and Hyperuricemia: A Randomized Trial.

This 12-week, open-label, active-comparator randomized trial compared calorie-restricted carbohydrate-restricted, DASH, and low-purine balanced diets in 102 men with overweight or obesity and hyperuricemia.

Diabetes CareOct 21, 2026Read summary
Clinical ResearchEndocrinology

The Effect of Obesity on the α-Cell Response to Hyperglycemia in the Presence of Amino Acids.

This randomized, two-occasion study examined how amino acids affect glucagon suppression during graded glucose infusion in lean participants and participants with obesity, with or without hepatic steatosis.

DiabetesOct 21, 2026Read summary
Clinical ResearchEndocrinology

Evaluating Improvement in Pain and Sensory Function When Using High-Frequency (10-kHz) Spinal Cord Stimulation in Individuals With Painful Diabetic Neuropathy: A Multicenter Randomized Controlled Trial (PDN-Sensory).

The multicenter randomized controlled PDN-Sensory trial evaluated 10-kHz spinal cord stimulation (SCS) plus conventional medical management (CMM) versus CMM alone in people with painful diabetic neuropathy.

Diabetes CareOct 21, 2026Read summary
Case ReportOphthalmology

METASTATIC UROTHELIAL CARCINOMA OF THE BLADDER TO THE RETINA: A CLINICOPATHOLOGIC CORRELATION AND REVIEW OF THE LITERATURE.

A patient with urothelial carcinoma of the bladder had a large yellow-white lesion in the superotemporal retina of the left eye.

RetinaOct 21, 2026Read case
Clinical ResearchEndocrinology

Baseline Serum Metabolites as Predictors of Teplizumab Response in Individuals With Type 1 Diabetes.

This analysis examined whether baseline serum metabolites could predict response to teplizumab in 41 people newly diagnosed with type 1 diabetes who participated in the randomized AbATE trial.

DiabetesOct 21, 2026Read summary
Clinical ResearchOphthalmology

EVALUATING THE EFFICACY AND SAFETY OF TOPICAL DIFLUPREDNATE IN PATIENTS WITH CHRONIC CENTRAL SEROUS CHORIORETINOPATHY.

This pilot, open-label randomized controlled trial compared topical difluprednate, oral eplerenone, and observation in adults with chronic or relapsing central serous chorioretinopathy.

RetinaOct 21, 2026Read summary
Clinical ResearchOphthalmology

EFFICACY AND SAFETY OF SUBTHRESHOLD LASER IN PATIENTS WITH ACUTE CENTRAL SEROUS CHORIORETINOPATHY: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed the efficacy and safety of subthreshold laser for acute central serous chorioretinopathy (CSC), including six randomized controlled trials with 401 participants.

RetinaOct 21, 2026Read summary
Clinical ResearchOphthalmology

ULTRAWIDE-FIELD COLOR FUNDUS IMAGES AND ARTIFICIAL INTELLIGENCE FOR DIAGNOSIS OF DIABETIC RETINOPATHY: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed artificial intelligence (AI) for diabetic retinopathy (DR) evaluation using ultrawide-field fundus images.

RetinaOct 21, 2026Read summary
Case ReportCardiology

Aspiration Thrombectomy for High-Risk Pulmonary Embolism With Life-Threatening Anemia and Active Uterine Bleeding: A Case Report.

A 48-year-old woman presented with shock, critical anemia (hemoglobin 41 g/L), and ongoing uterine bleeding associated with adenomyosis.

Am J Case RepOct 21, 2026Read case
Case ReportDermatology

5-Aminolevulinic acid-based photodynamic therapy used as a long-term management approach for refractory lichen sclerosus.

A 37-year-old man with more than 10 years of genital lichen sclerosus had recurrence after surgical resection, which left permanent anatomical deformity.

J Dermatolog TreatOct 21, 2026Read case
Clinical ResearchPreventive Medicine / Public HealthOpen access

Evaluating a multi-vaccine respiratory immunization strategy involving SARS-CoV-2, pneumococcal, and influenza vaccines in adults: A randomized, open-label, multicenter, controlled, non-inferiority Phase IV trial in China.

This randomized, open-label, multicenter Phase IV trial in China assessed immunogenicity and safety when adults aged ≥18 years received an inactivated SARS-CoV-2 vaccine with PPV23 and IIV4, compared with separate…

Hum Vaccin ImmunotherOct 21, 2026Read summary

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