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1616 articles
October 202624
Denecimig (Mim8) prophylaxis once every 2 weeks for hemophilia A with or without inhibitors: 26-week results from FRONTIER4.
This open-label extension study evaluated every-2-week (Q2W) denecimig prophylaxis in patients aged ≥12 years with hemophilia A, with or without inhibitors, who had previously received denecimig in a phase 2 study and…
Approach to the patient with APS-1/APECED.
This article presents five cases of autoimmune polyendocrine syndrome type 1 (APS-1/APECED), a disorder caused by impaired immune tolerance and typically associated with biallelic AIRE variants.
Bone phenotype of patients with genetic forms of lipodystrophy: a systematic review of literature.
This systematic review examined bone manifestations in people with genetic lipodystrophies, using human studies identified through searches of PubMed, EMBASE, and the Cochrane Library.
The extra X chromosome and autoimmune susceptibility in Klinefelter syndrome.
This systematic review and meta-analysis assessed autoimmune susceptibility in people with Klinefelter syndrome (47,XXY), using studies of autoimmune disease and serological markers.
Dysregulation of glycogen metabolism in cardiomyopathy caused by glycogenin-1 (GYG1) missense variants.
The report describes a new case of glycogen storage disease type 15 (GSD15), alongside analysis of heart explants from two previously reported patients.
Retatrutide and lipid and metabolite profiles in participants with obesity with or without type 2 diabetes.
This post hoc exploratory analysis of two randomized, placebo-controlled phase 2 trials examined fasting plasma metabolite and lipid changes with retatrutide in participants with obesity, with or without type 2…
Chios Mastic in Well-Controlled Hypertension: Findings From the HYPER-MASTIC Randomized Controlled Trial.
This double-blind, randomized, placebo-controlled trial assessed whether Chios mastic provides additional cardiovascular benefits in 106 adults with stable, well-controlled hypertension.
Sleep apnea-hypopnea in children: Evidence that Lize Tongqi decoction with acupuncture, moxibustion, and Xinwu acupoint stimulation is superior to standard Western treatment using montelucast/mometasone furoate.
This randomized controlled trial compared a combined traditional Chinese medicine and acupuncture-based regimen with montelukast plus mometasone in 60 children with snoring (mean age 7.9 years).
Tranilast/roxithromycin with topical tacrolimus in refractory atopic facial eczema: Case report.
A 30-year-old man with atopic dermatitis had facial eczema and severe itching that persisted despite conventional treatment, including oral betamethasone.
Tislelizumab-induced hyperamylasemia: Case report and safety analysis using the FAERS database.
A 69-year-old patient developed hyperamylasemia after six cycles of combination immunotherapy with pemetrexed, tislelizumab, and carboplatin. The authors attributed the elevated amylase to tislelizumab.
Crystalline κ light-chain proximal tubulopathy and Auer rod-like inclusions presenting as Fanconi syndrome: A case report.
A 53-year-old man presented with Fanconi syndrome, with hypokalemia, hypophosphatemia, mild metabolic acidosis, and renal glucosuria.
Variability in belumosudil exposure due to coadministration of voriconazole and isavuconazole in a patient with chronic graft-versus-host disease: Case report.
A man in his 50s with steroid-refractory pulmonary chronic graft-versus-host disease after cord blood transplantation received belumosudil, increased from 200 mg once daily to 200 mg twice daily.
Cardiac arrest in an adolescent following an overdose of antidepressants comprising sertraline, quetiapine fumarate, and lamotrigine: Case report.
An 11-year-old with depression ingested large quantities of sertraline (3 g), quetiapine fumarate (5 g), and lamotrigine (3 g).
Large Carinal Chondrosarcoma: Resection of the Main Carina, Distal Trachea, and Orifices of the Mainstem Bronchi and Construction of a New Carina.
A 23-year-old man presented with dyspnea, fatigue, and cough. CT showed a lobulated mass anterior to the distal trachea and main carina; bronchoscopy demonstrated carinal widening, significant stenosis of both mainstem…
Psychological factors impeding the progress of labor: case observations and the need for a multidisciplinary approach.
This report describes four labor cases with impaired or arrested progression and psychological factors, without identifiable obstetric pathology.
Participant Characteristics Associated With Loneliness Reduction During a Digital Social Robot Intervention Among Older Adults Living Alone in Japan: Secondary Analysis of a Randomized Controlled Trial.
This secondary analysis of a randomized controlled trial examined whether participant characteristics were associated with changes in loneliness during a digital social robot intervention among community-dwelling older…
Artificial intelligence-enhanced electrocardiography for predicting mortality and major adverse cardiovascular events: A systematic review and narrative synthesis.
This systematic review and narrative synthesis evaluated AI-enabled 12-lead or single-lead ECG models for predicting all-cause mortality, cardiovascular mortality, and major adverse cardiovascular events in adults.
SOX10 Expression in Primary Salivary Gland Tumors: A Meta-Analysis.
This PRISMA-guided systematic review and meta-analysis assessed SOX10 immunohistochemical expression across primary salivary gland tumors. It included 35 studies comprising 1146 histological and 35 cytological samples.
Management of extravasations of enfortumab vedotin and pembrolizumab: a case report and mini review of the current literature.
A 56-year-old patient with metastatic urothelial carcinoma developed extravasation of enfortumab vedotin and pembrolizumab during the first treatment cycle after the port catheter dislocated from the cephalic vein.
Effectiveness of different autologous platelet concentrates for orthodontic canine retraction following premolar extraction: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed platelet-rich plasma (PRP), injectable platelet-rich fibrin (i-PRF), and leukocyte-platelet-rich fibrin (L-PRF) for accelerating orthodontic canine retraction after…
Lymphoplasmacytic Lymphoma Involving Marrow-Containing Submandibular Heterotopic Ossification: A Case Report and Literature Review.
A 77-year-old man presented with a gradually enlarging, increasingly uncomfortable calcified nodule in the left submandibular region.
Safety and efficacy of a novel miniaturized robotic assisted surgery system in hysterectomy: a prospective, investigational device exemption clinical trial.
This prospective, multicentre, non-randomised Investigational Device Exemption trial assessed the safety and effectiveness of the MIRA miniaturized robotic system for benign hysterectomy.
Acute management of pelvic ring injuries: identifying common treatment principles across institutional algorithms.
This PRISMA-guided systematic review compared published institutional algorithms for acute pelvic ring injury management. Searches identified 25 studies describing algorithms, pathways, or protocols published from 2006…
Preoperative ureteral rest and outcomes of robot-assisted upper urinary tract reconstruction: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether preoperative ureteral rest is associated with outcomes after robot-assisted ureteral reconstruction or pyeloplasty.
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