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1704 articles

October 202624

Clinical ResearchPsychiatry

Cannabis use and subsequent onset of manic symptoms and bipolar disorder: A systematic review and meta-analysis.

This registered systematic review and meta-analysis examined longitudinal observational studies of people without prior bipolar disorder, comparing those exposed and unexposed to cannabis.

J Affect DisordOct 6, 2026Read summary
Clinical ResearchPsychiatry

Exercise to enhance antipsychotic effectiveness and mitigate metabolic harm: systematic review and meta-analysis.

This systematic review and meta-analysis pooled randomised controlled trials of supervised exercise in adults receiving antipsychotic medication for psychotic disorders.

J Affect DisordOct 6, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Maternal circulating cytokine and chemokine levels during pregnancy and risk of autism spectrum disorder in offspring: A systematic review and meta-analysis.

This systematic review and meta-analysis examined whether maternal blood cytokine and chemokine levels during pregnancy were associated with autism in offspring, drawing on seven human observational studies.

Neurosci Biobehav RevOct 6, 2026Read summary
Clinical ResearchGeneral Surgery

Hernia, mesh, microbes, and phage promise: Mapping 35 years of evidence through a systematic review.

This systematic review examined published evidence on microbiology and outcomes of hernia mesh infections, including studies from 1990–2025. Of 584 studies meeting inclusion criteria, 32 contributed to meta-analysis.

J Infect Public HealthOct 6, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Interactions between vaginal, periurethral and urinary microbiota in genitourinary syndrome of menopause and the effects of local estrogen therapy.

This prospective study characterized vaginal, periurethral, and bladder microbiota in postmenopausal women grouped by atrophy and symptom status, and assessed changes after 12 weeks of vaginal estriol.

MaturitasOct 6, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Long-Term Effects of Biliopancreatic Diversion (BPD), Biliopancreatic Diversion with Duodenal Switch (BPD-DS), and Single Anastomosis Duodeno‑Ileal Bypass with Sleeve Gastrectomy (SADI‑S) in Patients with Obesity: A Meta-Analysis.

This systematic review and meta-analysis assessed outcomes at 10 or more years after biliopancreatic diversion (BPD), BPD with duodenal switch (BPD-DS), and single-anastomosis duodeno-ileal bypass with sleeve…

Obes SurgOct 6, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Metabolic Bariatric Surgery for Cancer Prevention and Risk Reduction in Patients with Obesity: A GRADE-Based International Federation for the Surgery and Other Therapies for Obesity (IFSO) Position Statement.

This GRADE-based international position statement systematically reviewed evidence on metabolic bariatric surgery (MBS) and cancer incidence in adults with obesity, comparing surgery with non-surgical weight-loss…

Obes SurgOct 6, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Frequent Versus Single Active Bouts Differentially Affect Movement Behavior and Energy Balance in Adults With Overweight/Obesity.

This randomized controlled trial compared frequent short walking bouts with one continuous bout in 30 adults with overweight or obesity.

Obesity (Silver Spring)Oct 6, 2026Read summary
Clinical ResearchGeriatrics

The Effect of a Very Low-Carbohydrate Diet on Intermuscular Adipose Tissue and Muscle Function in Older Adults With Obesity.

This randomized controlled trial compared a weight-maintaining very low-carbohydrate diet (VLCD) with a low-fat diet (LFD) over 8 weeks in adults aged 60 years or older with obesity.

Obesity (Silver Spring)Oct 6, 2026Read summary
Clinical ResearchOncology (Medical)

MK-4002, a B-cell maturation antigen-targeting T-cell engager, in relapsed or refractory multiple myeloma: a first-in-human, open-label, phase 1 study.

This first-in-human, open-label, multicentre phase 1 study evaluated the safety, pharmacokinetics, and preliminary activity of the BCMA-targeting T-cell engager MK-4002 in adults with heavily pretreated relapsed or…

Lancet HaematolOct 6, 2026Read summary
Clinical ResearchNeurology

Bilateral gamma knife radiosurgery in severe essential tremor: a prospective trial.

This phase II prospective trial evaluated the safety and efficacy of staged bilateral Gamma Knife radiosurgery (GKS) of the ventral intermedius thalamic nucleus in 33 patients with severe essential tremor.

BrainOct 5, 2026Read summary
Case ReportObstetrics & Gynecology

World's first case report of live birth following autologous ovarian tissue cryopreservation and transplantation in a patient with colon carcinoma.

A 29-year-old woman with colon cancer underwent ovarian tissue cryopreservation prior to chemotherapy. After developing premature ovarian insufficiency, she received two transplantations of thawed ovarian cortex strips.

Gynecol EndocrinolOct 5, 2026Read case
Clinical ResearchPsychiatry

Systematic review and meta-analysis: the effectiveness of cognitive behavioral therapy and eye movement desensitization and reprocessing in children and adolescents.

This systematic review and meta-analysis evaluated the effectiveness of cognitive behavioral therapy (CBT) versus eye movement desensitization and reprocessing (EMDR) for treating PTSD in children and adolescents aged…

Eur J PsychotraumatolOct 5, 2026Read summary
Case ReportObstetrics & Gynecology

Navigating the unexpected: management of incidental severe Factor V deficiency in term pregnancy.

A primigravida was found to have severe Factor V deficiency (<1% activity) during routine preoperative evaluation for an elective caesarean section, despite being asymptomatic and having no bleeding history.

BMJ Case RepOct 5, 2026Read case
Case ReportOncology (Medical)

Adrenal metastasis from papillary thyroid cancer: staged surgical resection.

A man in his 70s with a history of papillary thyroid carcinoma presented with recurrence in the right cervical lymph nodes and a right adrenal mass measuring 5.7×6.5 cm. A CT-guided biopsy confirmed metastatic disease.

BMJ Case RepOct 5, 2026Read case
Case ReportGastroenterology

Gastrointestinal manifestations of IgA vasculitis guiding treatment in an adult patient.

A man in his 20s presented with abdominal pain, post-prandial vomiting, a purpuric rash, arthralgia, and hypertension. Urine studies indicated subnephrotic range proteinuria, and colonoscopy revealed ileal ulceration.

BMJ Case RepOct 5, 2026Read case
Case ReportEndocrinology

Refractory amiodarone-induced thyrotoxicosis causing malignant arrhythmias, treated with therapeutic plasma exchange-bridged thyroidectomy.

A man in his mid-60s with severe cardiomyopathy developed refractory amiodarone-induced thyrotoxicosis, leading to recurrent ventricular tachycardia.

BMJ Case RepOct 5, 2026Read case
Case ReportHematology

Reduced venesection requirement as a clue to occult colorectal cancer in hereditary haemochromatosis.

A man in his late 70s with hereditary haemochromatosis experienced an unexpected cessation of his usual venesection for iron management, despite no gastrointestinal symptoms or anemia.

BMJ Case RepOct 5, 2026Read case
Case ReportPediatrics

Cutaneous tumbu fly myiasis in a returning child traveller and a novel EMLA-assisted extraction technique in paediatric emergency care.

A toddler presented with cutaneous myiasis and cellulitis after traveling to Gambia, caused by Cordylobia anthropophaga. The case was managed using a novel non-operative technique involving eutectic mixture of local…

BMJ Case RepOct 5, 2026Read case
Case ReportDermatology

Cutaneous leukocytoclastic vasculitis with concurrent colitis of uncertain aetiology.

A female in her 20s presented with biopsy-confirmed cutaneous leukocytoclastic vasculitis and significant gastrointestinal symptoms, including recurrent rectal bleeding and abdominal pain.

BMJ Case RepOct 5, 2026Read case
Case ReportPediatrics

Comprehensive dental management of odontogenic infection and ankyloglossia under general anaesthesia in a medically complex child with intellectual disability.

A middle childhood child with moderate intellectual disability presented with pain and swelling in the right posterior mandibular area.

BMJ Case RepOct 5, 2026Read case
Case ReportUrology

Peritoneal loose body: an incidental finding, a challenging diagnosis and multimodal assessment to avoid resections.

A man in his early 40s presented with urinary symptoms and was found to have a right ureteric calculus, hydronephrosis, and a urinary tract infection.

BMJ Case RepOct 5, 2026Read case
Case ReportEndocrinology

Myxoedema coma in a patient with alcohol dependence: a diagnostic pitfall.

A man in his sixties with known hypothyroidism and alcohol dependence presented with profound hypothermia, refractory hypoglycaemia, hypoxia, and reduced consciousness.

BMJ Case RepOct 5, 2026Read case
Case ReportOphthalmology

Uveitis despite adalimumab therapy in Blau syndrome.

A middle childhood boy initially diagnosed with oligoarticular juvenile idiopathic arthritis presented with persistent arthritis, recurrent fever, and skin lesions.

BMJ Case RepOct 5, 2026Read case

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