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1719 articles
October 202624
Mediation Analysis of Urine Osmolality and Response to Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Assessment.
This post hoc analysis of the TEMPO 3:4 randomized controlled trial evaluated urine osmolality (Uosm) as a biomarker for long-term response to tolvaptan in patients with autosomal dominant polycystic kidney disease…
Efficacy and Safety of PD-1/PD-L1 Inhibitors Combined With Anti-Angiogenic Tyrosine Kinase Inhibitors for Recurrent or Metastatic Nasopharyngeal Carcinoma: A Systematic Review and Single-Arm Meta-Analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of PD-1/PD-L1 inhibitors combined with anti-angiogenic tyrosine kinase inhibitors in 357 patients with recurrent or metastatic nasopharyngeal…
Hereditary Spastic Paraplegia Type 11: A Comprehensive Case Report.
An 18-year-old woman with no significant medical history presented with a 2-year history of progressive weakness and stiffness in both lower limbs, leading to difficulty in walking.
A Mysterious Case of Giant Scalp Devil's Horn with Intracranial Extension Removed by Surgical Excision.
A 60-year-old male presented with altered consciousness, chronic headaches, blurred vision, and scalp swelling. Imaging revealed a giant cutaneous horn in the scalp with underlying bony erosion and intracranial…
The Urgent Surgical Outcome of Intracranial Subdural Empyema: A Case Presentation.
A patient presented unconscious due to intracranial subdural empyema, a severe brain infection. Urgent surgical intervention was performed, leading to a rapid recovery postoperatively.
Intermittent Pneumatic Compression in Patients with Postmastectomy Lymphedema: A Randomized Controlled Trial.
This randomized controlled trial evaluated the effects of intermittent pneumatic compression (IPC) combined with exercises on upper limb lymphedema in 21 patients post-mastectomy.
Association of Sarcopenia With Global, Motor, Cognitive, and Swallowing Function Prognosis in Stroke Patients: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the impact of sarcopenia on functional outcomes in stroke patients. Analyzing 36 cohort studies, it found that patients with sarcopenia had a significantly higher risk…
Human Infection with Japanese Encephalitis Virus Genotype V, China, 2025.
A human case of Japanese encephalitis virus genotype V (JEV GV) was confirmed in China through serological testing, sequencing, and quantitative reverse transcription PCR.
Chlamydia psittaci Meningitis, Chile, 2023.
A 50-year-old farm worker in Chile presented with meningitis, which was confirmed to be caused by Chlamydia psittaci through cerebrospinal fluid quantitative real-time PCR and serology.
Pharmacokinetic and Pharmacodynamic Drug-Drug Interactions Between Cofrogliptin and Metformin in Healthy Subjects: A Single-Center, Single-Arm, Phase I Study in China.
This single-center, single-arm Phase I study assessed drug-drug interactions between cofrogliptin and metformin in 22 healthy Chinese subjects.
A Phase I Study of Nimotuzumab Combined with Irinotecan in Chinese Patients with Advanced Solid Tumors.
This Phase I study assessed the pharmacokinetics and safety of nimotuzumab combined with irinotecan in Chinese patients with advanced solid tumors.
Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults.
This Phase I randomized controlled trial evaluated the pharmacokinetics, immunogenicity, and safety of REGN17092, a modified YTE antibody targeting SARS-CoV-2, in 40 healthy adults.
Buruli Ulcer Acquired From Ringtail Possum Rescue.
A patient presented with a Buruli ulcer, which was likely acquired from a scratch by a ringtail possum during a rescue attempt. This case highlights a newly recognized transmission route for Buruli ulcer.
Enhanced recovery after colorectal surgery in patients with inflammatory bowel disease to reduce hospital length of stay: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of enhanced recovery after surgery (ERAS) protocols on adult patients with inflammatory bowel disease (IBD).
Systematic Review and Meta-analysis of Group B Streptococcus Rectovaginal Colonization Rates and Serotype Distribution among Pregnant Women, Asia-Pacific Region, 2014-2025.
This systematic review and meta-analysis examined group B Streptococcus (GBS) rectovaginal colonization rates among 978,150 pregnant women in the Asia-Pacific region.
Meta-analysis of Maternal and Fetal Outcomes of Crimean-Congo Hemorrhagic Fever during Pregnancy.
This meta-analysis examined the maternal and fetal outcomes of Crimean-Congo hemorrhagic fever (CCHF) in 55 pregnancies. The study found a maternal mortality rate of 28.8% and a fetal loss rate of 57.4%.
Meta-analysis of Asymptomatic Monkeypox Virus Prevalence in Nonendemic Regions, 2022-2024.
This meta-analysis examined the prevalence of asymptomatic monkeypox virus (MPXV) detections in nonendemic regions from May 2022 to September 2024.
A Systematic Review and Meta-Analysis of the Prevention and Management of Pediatric Urinary Tract Infection and Suspected Urinary Tract Infection: Technical Report.
This systematic review and meta-analysis evaluated management strategies for pediatric urinary tract infections (UTIs) in children without known anatomic anomalies, including antibiotic duration and route, and the use…
A Systematic Review and Meta-Analysis of the Role of Ultrasonography for the Diagnosis of Vesicoureteral Reflux in Pediatric Patients Following Urinary Tract Infections: Technical Report.
This systematic review and meta-analysis evaluated the diagnostic accuracy of renal and bladder ultrasonography (RBUS) for detecting vesicoureteral reflux (VUR) in pediatric patients post-urinary tract infection (UTI).
Pediatric Literacy Promotion for Latino Families by Texts and Referrals: A 3-Arm RCT.
This randomized controlled trial evaluated two strategies to enhance literacy promotion among 630 Latino caregiver-infant dyads.
Behavioral Interventions in Pediatric Type 1 Diabetes Management: An Updated Meta-Analysis.
This updated meta-analysis evaluated the impact of behavioral interventions on hemoglobin A1C (HbA1C) in youths with type 1 diabetes (T1D) across 46 randomized controlled trials.
Hereditary TTP and Hemolytic Anemia in Newborns.
This case report discusses three siblings diagnosed with hereditary thrombotic thrombocytopenic purpura (hTTP) due to ADAMTS13 deficiency, presenting with severe jaundice at birth.
Black Pleural Effusion as a Rare Presentation of Serotype 3 Pneumococcal Empyema.
A previously healthy 6-year-old boy presented with severe pneumonia, leading to the discovery of a black pleural effusion during thoracentesis.
Spread and Sustainability of an Antimicrobial Stewardship Initiative Within a Pediatric Network.
This randomized controlled trial evaluated the sustainability of an antimicrobial stewardship initiative in a pediatric network, focusing on prescribing practices for skin and soft tissue infections (SSTI).
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