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1616 articles
October 202624
Ruxolitinib for the treatment of pediatric acute and chronic steroid-refractory graft-versus-host disease: Efficacy, safety, and outcomes.
This single-center retrospective study assessed ruxolitinib in children under 18 years with steroid-refractory graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Semaglutide modulates explore/exploit decision-making in major depressive disorder: A randomized clinical trial.
This secondary analysis of a randomized clinical trial examined whether semaglutide affected explore/exploit decision-making in 72 participants with major depressive disorder (MDD).
Ultra high-density, 4096-channel intraoperative neurophysiological brain mapping for functional localization of the human central sulcus.
During resection of a right parafalcine meningioma in a 56-year-old man, four flexible 1024-electrode micro-ECoG arrays were used to record somatosensory evoked potentials from the peri-Rolandic cortex during…
Co-occurrence of aortic dissection and polycystic kidney disease: a case report.
A 19-year-old Caucasian man with no known medical history collapsed during sexual intercourse and died. Post-mortem examination found hemopericardium and aortic dissection in association with polycystic kidney disease…
Seated Modified Liuzijue Training for Rehabilitation of a Patient with Respiratory Impairment During the Recovery Phase of Stroke: A Case Report.
A patient with respiratory impairment during stroke recovery also had motor dysfunction and balance limitations that made the traditional standing Liuzijue protocol unsuitable.
Extended Ceftriaxone Prophylaxis and Postoperative Inflammation and Infection-Related Symptoms After Ureteral Lithotripsy with Negative Urine Cultures.
This single-center exploratory study, reported as randomized, compared extended preoperative ceftriaxone with a single prophylactic dose in 252 patients with negative urine cultures undergoing rigid ureteroscopic…
Additional Functional Exercise Training Improves Knee Recovery After Meniscus Repair: A Randomized Controlled Trial.
This prospective randomized controlled trial assessed whether functional exercise training (FET) added to conventional rehabilitation improves recovery after meniscus repair.
Thermographic outcomes of auricular laser acupuncture and auricular seed acupressure in older adults with chronic shoulder pain: an exploratory nonrandomized, nonconcurrent comparison.
This exploratory, open-label, nonrandomized comparison studied 20 adults aged 60–90 years with chronic shoulder pain, allocated by order of entry to auricular laser acupuncture or seed acupressure.
"The Effect of Forgiveness Psychoeducation on Death Anxiety, Caregiver Burden, and Forgiveness Tendencies in Caregivers of Patients at the End of Life: A Randomized Controlled Trial": Şahin 49(3) May/June 2026.
This randomized controlled trial evaluated forgiveness psychoeducation for 56 caregivers of patients at the end of life, with 28 assigned to the intervention and 28 to a no-intervention control group.
Effectiveness and safety of atorvastatin/ ezetimibe fixed-dose combination in hypercholesterolemia: a systematic review and network meta-analysis.
This systematic review and network meta-analysis compared atorvastatin alone with atorvastatin/ezetimibe free-equivalent and fixed-dose combinations in people with hypercholesterolemia.
Phase 2 trial to evaluate the safety and immunogenicity of a 25-valent pneumococcal conjugate vaccine (IVT-PCV25) in infants.
This double-blind, randomised phase 2 trial in 421 healthy infants in the Philippines compared three dose-ranging formulations of the 25-valent pneumococcal conjugate vaccine IVT-PCV25 with licensed Prevnar-20.
The Improvement in the Clinical Management of Patients Undergoing Palliative Care After Training the Primary Care Team by a Specialized Team: A Systematic Review.
This systematic review assessed whether palliative care training for healthcare professionals in primary care improves symptom assessment and clinical management. Eight studies with varied designs were included.
Bronchial Thermoplasty in Severe Asthma: Bridging Randomised and Real-World Evidence: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed bronchial thermoplasty (BT) efficacy and safety in adults with severe uncontrolled asthma, analysing randomised controlled trials (RCTs) separately from observational…
Prophylactic Low-Dose Esketamine for Prevention of Intraoperative Penile Erection During Ureteroscopic Surgery Under General Anesthesia: A Randomized, Double-Blind, Placebo-Controlled Trial.
Intraoperative penile erection (IPE) during ureteroscopic surgery may interrupt surgical procedures and increase the risk of urethral injury.
Natural History and Therapeutic Response in Ophthalmic Plasminogen Deficiency: Two Cases and Call for Registry-Based Data.
The report describes two patients with type 1 plasminogen deficiency and ligneous conjunctivitis. A 65-year-old woman with untreated disease had recurrent conjunctivitis, ultimately requiring enucleation, and developed…
Impact of violence on HIV outcomes among female sex workers: A global systematic review and meta-analysis.
This global systematic review and meta-analysis examined associations between violence and HIV outcomes among female sex workers (FSW). It included 94 studies, 226 estimates and 186,613 FSWs across 39 countries.
Direct and indirect entomological efficacy of Targeted Indoor Residual Spraying against Aedes aegypti in Iquitos, Peru.
This entomological cluster-randomized controlled trial in Iquitos, Peru, compared targeted indoor residual spraying (TIRS) with standard Ministry of Health vector-control activities.
Endometrial ablation plus levonorgestrel-releasing intrauterine system versus endometrial ablation alone in women with heavy menstrual bleeding in The Netherlands (MIRA2): a multicentre, open-label, randomised, controlled, superiority trial.
MIRA2 was a multicentre, open-label, randomised controlled superiority trial in women younger than 60 years with heavy menstrual bleeding eligible for endometrial ablation.
Disease-free survival and overall survival after neoadjuvant immunotherapy in mismatch repair-deficient colon cancer in the Netherlands: results of the single-arm, multicentre, phase 2, NICHE-2 trial.
This single-arm, multicentre phase 2 trial assessed neoadjuvant ipilimumab plus nivolumab followed by surgery in previously untreated patients with resectable stage 2 or 3 mismatch repair-deficient colon cancer.
A Systematic Review of Complications Following Elective Foot and Ankle Surgery.
This systematic review synthesized complication profiles and risk factors in adults undergoing elective foot and ankle surgery.
Teclistamab Induced a Profound Hematologic Response in Light Chain Deposition Disease With Probable Cardiac Involvement.
A 63-year-old man had κ-light chain deposition disease involving the kidneys, with probable cardiac involvement. After an initial response to daratumumab-pomalidomide-dexamethasone, he developed hematologic relapse.
Primary intracranial sarcoma, DICER1-mutant: 5 cases highlighting variable clinical and molecular features.
The report describes five patients aged 6 to 40 years with primary intracranial sarcoma, DICER1-mutant, identified through methylation profiling and/or sequencing.
Selective recovery effects of short-term beetroot juice supplementation after exercise-induced muscle damage in trained female volleyball players.
This randomized, double-blind, placebo-controlled crossover trial examined short-term beetroot juice (BRJ) supplementation after exercise-induced muscle damage in trained female university volleyball players.
Placebo effects of caffeine on sport performance: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether deceptively describing a placebo as caffeine affects sport performance in healthy adults.
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