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1616 articles
October 202624
PD-1/ PD-l1 Inhibitors and Stereotactic Radiosurgery for Brain Metastases: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed efficacy and toxicity when PD-1/PD-L1 inhibitors were combined with stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy (FSRT) for…
Systematic review and meta-analysis on comparing treatment approaches of cervical fractures in ankylosing spondylitis to determine improvement in outcomes.
This systematic review and meta-analysis compared anterior, posterior, and combined surgical approaches for cervical fractures in patients with ankylosing spondylitis.
Symptom duration and postoperative outcomes in degenerative cervical myelopathy: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether symptom duration is associated with outcomes after surgery for degenerative cervical myelopathy (DCM).
Genetic correlates of corticobasal degeneration: a systematic review and meta-analysis.
This PRISMA-guided systematic review and meta-analysis synthesized genetic association studies of corticobasal degeneration (CBD), including 22 studies published between 2001 and 2025.
Inferolateral ST-Segment Elevation Myocardial Infarction Secondary to Suspected Coronary Embolism in a Patient with Paroxysmal Atrial Fibrillation: A Case Report.
A 76-year-old man with paroxysmal atrial fibrillation presented with acute substernal chest pain and inferolateral ST-segment elevation myocardial infarction.
Anatomical Correction of Adult Intestinal Malrotation Using Kareem's Procedure: A Case Report.
A 26-year-old woman presented with sudden severe colicky central abdominal pain, non-bilious vomiting, and complete constipation; she had experienced a similar self-limited episode a month earlier.
Local ancestry-aware genome-wide meta-analysis uncovers novel genetic loci for sickle cell disease nephropathy.
This local ancestry-aware genome-wide association meta-analysis examined estimated glomerular filtration rate in participants from two well-characterized adult sickle cell disease cohorts, seeking genetic loci…
Denecimig (Mim8) prophylaxis once every 2 weeks for hemophilia A with or without inhibitors: 26-week results from FRONTIER4.
This open-label extension study evaluated every-2-week (Q2W) denecimig prophylaxis in patients aged ≥12 years with hemophilia A, with or without inhibitors, who had previously received denecimig in a phase 2 study and…
Approach to the patient with APS-1/APECED.
This article presents five cases of autoimmune polyendocrine syndrome type 1 (APS-1/APECED), a disorder caused by impaired immune tolerance and typically associated with biallelic AIRE variants.
Bone phenotype of patients with genetic forms of lipodystrophy: a systematic review of literature.
This systematic review examined bone manifestations in people with genetic lipodystrophies, using human studies identified through searches of PubMed, EMBASE, and the Cochrane Library.
The extra X chromosome and autoimmune susceptibility in Klinefelter syndrome.
This systematic review and meta-analysis assessed autoimmune susceptibility in people with Klinefelter syndrome (47,XXY), using studies of autoimmune disease and serological markers.
Dysregulation of glycogen metabolism in cardiomyopathy caused by glycogenin-1 (GYG1) missense variants.
The report describes a new case of glycogen storage disease type 15 (GSD15), alongside analysis of heart explants from two previously reported patients.
Retatrutide and lipid and metabolite profiles in participants with obesity with or without type 2 diabetes.
This post hoc exploratory analysis of two randomized, placebo-controlled phase 2 trials examined fasting plasma metabolite and lipid changes with retatrutide in participants with obesity, with or without type 2…
Chios Mastic in Well-Controlled Hypertension: Findings From the HYPER-MASTIC Randomized Controlled Trial.
This double-blind, randomized, placebo-controlled trial assessed whether Chios mastic provides additional cardiovascular benefits in 106 adults with stable, well-controlled hypertension.
Sleep apnea-hypopnea in children: Evidence that Lize Tongqi decoction with acupuncture, moxibustion, and Xinwu acupoint stimulation is superior to standard Western treatment using montelucast/mometasone furoate.
This randomized controlled trial compared a combined traditional Chinese medicine and acupuncture-based regimen with montelukast plus mometasone in 60 children with snoring (mean age 7.9 years).
Tranilast/roxithromycin with topical tacrolimus in refractory atopic facial eczema: Case report.
A 30-year-old man with atopic dermatitis had facial eczema and severe itching that persisted despite conventional treatment, including oral betamethasone.
Tislelizumab-induced hyperamylasemia: Case report and safety analysis using the FAERS database.
A 69-year-old patient developed hyperamylasemia after six cycles of combination immunotherapy with pemetrexed, tislelizumab, and carboplatin. The authors attributed the elevated amylase to tislelizumab.
Crystalline κ light-chain proximal tubulopathy and Auer rod-like inclusions presenting as Fanconi syndrome: A case report.
A 53-year-old man presented with Fanconi syndrome, with hypokalemia, hypophosphatemia, mild metabolic acidosis, and renal glucosuria.
Variability in belumosudil exposure due to coadministration of voriconazole and isavuconazole in a patient with chronic graft-versus-host disease: Case report.
A man in his 50s with steroid-refractory pulmonary chronic graft-versus-host disease after cord blood transplantation received belumosudil, increased from 200 mg once daily to 200 mg twice daily.
Cardiac arrest in an adolescent following an overdose of antidepressants comprising sertraline, quetiapine fumarate, and lamotrigine: Case report.
An 11-year-old with depression ingested large quantities of sertraline (3 g), quetiapine fumarate (5 g), and lamotrigine (3 g).
Large Carinal Chondrosarcoma: Resection of the Main Carina, Distal Trachea, and Orifices of the Mainstem Bronchi and Construction of a New Carina.
A 23-year-old man presented with dyspnea, fatigue, and cough. CT showed a lobulated mass anterior to the distal trachea and main carina; bronchoscopy demonstrated carinal widening, significant stenosis of both mainstem…
Psychological factors impeding the progress of labor: case observations and the need for a multidisciplinary approach.
This report describes four labor cases with impaired or arrested progression and psychological factors, without identifiable obstetric pathology.
Participant Characteristics Associated With Loneliness Reduction During a Digital Social Robot Intervention Among Older Adults Living Alone in Japan: Secondary Analysis of a Randomized Controlled Trial.
This secondary analysis of a randomized controlled trial examined whether participant characteristics were associated with changes in loneliness during a digital social robot intervention among community-dwelling older…
Artificial intelligence-enhanced electrocardiography for predicting mortality and major adverse cardiovascular events: A systematic review and narrative synthesis.
This systematic review and narrative synthesis evaluated AI-enabled 12-lead or single-lead ECG models for predicting all-cause mortality, cardiovascular mortality, and major adverse cardiovascular events in adults.
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