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1064 articles
September 202624
Cognitive effects of ketamine and esketamine treatment for major depressive and bipolar disorder: a systematic review.
This systematic review assessed cognitive outcomes with ketamine and esketamine in adults with major depressive disorder, bipolar disorder, or treatment-resistant depression.
A systematic review of psychosocial interventions to increase adherence to medications for opioid use disorder.
This systematic review assessed randomized controlled trials of psychosocial interventions reporting medication adherence among people receiving medications for opioid use disorder (MOUD).
Feasibility and efficacy of an emotion-based online intervention for the treatment of anxiety and depression in people with cancer - Results of a randomized controlled trial.
This randomized controlled trial assessed the feasibility and efficacy of a 10-week emotion-based online psycho-oncological self-help intervention (epos) for adults with cancer who were receiving treatment or aftercare.
Remission status in persistent depressive disorder following acute treatment with psychotherapy plus medication or medication alone: A 2-year naturalistic follow-up.
This observational study followed patients with persistent depressive disorder (PDD) for two years after acute treatment with psychotherapy plus medication or medication alone.
Matrix metalloproteinase-9 is associated with CX3CL1 on tau and amyloid biomarker pathways in APOE4 carriers.
This randomized controlled trial investigated the relationship between matrix metalloproteinase-9 (MMP-9) and CX3CL1 in cerebrospinal fluid biomarkers for amyloid and tau in cognitively unimpaired APOE ε4 carriers…
The effects of artificial intelligence-based chatbots on mental health: A systematic review and three-level meta-analysis.
This systematic review and three-level random-effects meta-analysis assessed AI-based chatbot interventions for mental health across 16 eligible studies, incorporating 67 effect sizes.
Efficacy and neural mechanisms of transcranial direct current stimulation for social function in children and adolescents with autism spectrum disorder: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed transcranial direct current stimulation (tDCS) for social functioning and neurophysiological outcomes in children and adolescents with autism spectrum disorder.
Efficacy of efgartigimod in the treatment of autoimmune encephalitis: a systematic review.
Autoimmune encephalitis (AE) encompasses a group of inflammatory disorders of the brain parenchyma mediated by autoimmune mechanisms.
Behaviourally informed text message reminders to increase cervical screening attendance in people with severe mental illness: the OPTIMISE pilot randomised controlled trial.
This pilot randomized controlled trial evaluated the feasibility of enhanced text message reminders to improve cervical screening attendance among individuals with severe mental illness (SMI) aged 24-64.
Efficacy of prescription-eligible digital health applications for depression and generalized anxiety disorder in Germany: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of prescription-eligible digital health applications (DiGA) for depression and generalized anxiety disorder in Germany, analyzing 19 randomized controlled…
Acute psychosis unmasking severe non-ischaemic cardiomyopathy with biventricular thrombosis and cardioembolic cerebral infarcts.
A woman in her early 30s with a history of major depressive disorder and generalized anxiety disorder presented with progressive paranoia and auditory hallucinations.
A Mobile App for Student Veterans With Co-Occurring Academic and Psychiatric Concerns: Pilot Usability and Feasibility Study.
This pilot usability and feasibility study evaluated the VetEd mobile app designed for student veterans with co-occurring psychiatric concerns.
Toward personalized interventions for preventing depression in primary care: Qualitative and quantitative findings from the e-predictD pilot study.
The e-predictD pilot study evaluated a personalized intervention for preventing depression in primary care, involving 56 non-depressed patients at moderate-to-high risk.
Efficacy of tDCS-primed iTBS in major depressive disorder: A randomized, sham-controlled trial with exploratory resting motor threshold analyses.
This randomized, double-blind, sham-controlled trial evaluated the efficacy of cathodal transcranial direct current stimulation (tDCS) priming followed by intermittent theta burst stimulation (iTBS) in 76 patients with…
Brain serotonin transporter remains stable across seasons: A Bayesian and frequentist meta-analysis.
This meta-analysis examined seasonal variations in brain serotonin transporter (SERT) availability in healthy individuals using neuroimaging studies.
Dual-target deep brain stimulation for severe pediatric autism: Sustained core symptom reduction in a 12-month case study.
A 9-year-old girl with severe autism spectrum disorder (ASD) and intellectual disability underwent bilateral deep brain stimulation (DBS) targeting the anterior limb of the internal capsule and nucleus accumbens.
Diagnostic-mortality discordance in ischaemic heart disease among patients with schizophrenia: A systematic review and meta-analysis.
This systematic review and meta-analysis examined observational evidence on ischaemic heart disease (IHD) risk, diagnosis, and mortality among people with schizophrenia.
Predicting conversion from mild cognitive impairment to Alzheimer's disease: A systematic review of deep learning models for early-stage disease classification.
This PRISMA-guided systematic review assessed deep learning approaches for classifying Alzheimer’s disease stages and predicting conversion from mild cognitive impairment (MCI) to Alzheimer’s disease.
Burnout and secondary traumatic stress in child protection workers: Untangling the role of personal and work-related factors using meta-analysis.
This systematic review and meta-analysis examined personal and work-related factors associated with burnout and secondary traumatic stress (STS) among child protection workers.
The efficacy of modified psychodynamic psychotherapy for patients with schizophrenia-spectrum disorders in Germany: a prospective, single-centre, assessor-blinded, parallel-group, randomised controlled trial.
This randomized controlled trial evaluated the efficacy of Modified Psychodynamic Psychotherapy for Schizophrenia (MPP-S) combined with treatment as usual (TAU) in 130 outpatients with schizophrenia-spectrum disorders…
Comparative effectiveness of mood stabiliser monotherapy versus second-generation antipsychotic monotherapy versus combination therapy for continuation and maintenance treatment after a first episode of psychotic mania in North America, Chile, and Spain: a target trial emulation using data from the BD-CAUSAL Collaboration.
This pragmatic clinical trial evaluated the effectiveness of mood stabiliser monotherapy, second-generation antipsychotic monotherapy, and combination therapy in individuals aged 16 and older after a first episode of…
Effects of Digital Mental Health Screening Alone and With the Online MINDBODYSTRONG CBT-Based Program on Burnout, Depression, Anxiety, Healthy Behaviors, and Suicidal Ideation in at-Risk Nurses at 3- and 6-Months Post-Intervention: An RCT.
This randomized controlled trial evaluated the effects of a digital mental health screening program alone versus combined with the MINDBODYSTRONG CBT-based program on burnout, depression, anxiety, and suicidal ideation…
Association between sleep paralysis and anxiety: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the association between sleep paralysis and anxiety, involving 5568 participants across 11 studies.
Global prevalence and patterns of benzodiazepine use among adolescents and young adults: A systematic review and meta-analysis.
This systematic review and meta-analysis synthesised observational studies of benzodiazepine use among adolescents and young adults aged 16–30 years. Fifteen studies involving 7,235,912 participants were included.
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