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1998 articles

October 202624

Case ReportDermatology

Oral mucous membrane pemphigoid as a window to systemic autoimmunity: two cases associated with rheumatoid arthritis and Sjögren's disease.

Two women presented with oral mucous membrane pemphigoid (MMP) in the setting of systemic autoimmunity. A 68-year-old woman with longstanding rheumatoid arthritis had recurrent oral ulcerations confirmed as MMP on…

Einstein (Sao Paulo)Oct 19, 2026Read case
Clinical ResearchPhysical Medicine & Rehabilitation

Loop Taping for Heel Fat Pad Syndrome: A Crossover Pilot Randomized Controlled Trial.

This two-period crossover pilot randomized controlled trial assessed loop taping in adults with heel fat pad syndrome, comparing it with control taping in randomized order.

J Foot Ankle ResOct 19, 2026Read summary
Clinical ResearchGeriatricsOpen access

Outdoor cycling competence and balance control in older adults - cross-sectional analysis of the BiPerAge trial.

This exploratory cross-sectional analysis used baseline data from a two-center randomized controlled trial to examine balance and outdoor cycling competence in 116 community-dwelling adults aged ≥ 65 years who made at…

BMC GeriatrOct 19, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Efficacy and safety of ifupinostat in relapsed or refractory diffuse large B-cell lymphoma: a multicenter, single-arm phase 2 study.

This multicenter, single-arm phase 2 study evaluated intravenous ifupinostat monotherapy in patients with relapsed or refractory diffuse large B-cell lymphoma after at least two prior systemic therapy lines.

Signal Transduct Target TherOct 19, 2026Read summary
Clinical ResearchCardiology

Safety and effectiveness of the Vertex Pulmonary Embolectomy System in acute intermediate-risk pulmonary embolism: the SPIRARE II pivotal trial.

SPIRARE II was a prospective, single-arm, multicentre pivotal trial evaluating the Vertex Pulmonary Embolectomy System for aspiration thrombectomy in patients with acute intermediate-risk pulmonary embolism.

EuroInterventionOct 19, 2026Read summary
Clinical ResearchEndocrinology

Whole egg consumption effects on vitamin D and carotenoids bioavailability in pre- and post-menopausal females: a randomized crossover controlled feeding trial.

This randomized crossover controlled-feeding trial examined whether whole eggs eaten with a cooked vegetable meal altered postprandial nutrient absorption in 9 pre-menopausal and 8 post-menopausal females.

Food FunctOct 19, 2026Read summary
Clinical ResearchFamily Medicine

AI-Based Clinical Decision Support Systems in Primary Care: Systematic Review of Clinical Implementation.

This systematic review assessed the effectiveness and safety of AI-based clinical decision support systems (AI-CDSSs) used by health professionals in primary care, compared with usual care or non-AI decision support.

J Med Internet ResOct 19, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Effectiveness of physical, psychological, and alternative interventions for post-COVID-19 condition: a systematic review.

This systematic review of randomized controlled trials assessed supervised, face-to-face non-pharmacological interventions in adults with WHO-defined post-COVID-19 condition.

J Rehabil MedOct 19, 2026Read summary
Case ReportOphthalmologyOpen access

Descemet stripping only combined with cataract surgery and extended-depth-of-focus intraocular lens implantation: a surgical strategy and exploratory clinical evidence.

Three patients with Fuchs endothelial dystrophy, preserved peripheral endothelium, and visually significant cataract underwent combined Descemet stripping only, phacoemulsification, and implantation of a Vivity…

Int OphthalmolOct 19, 2026Read case
Case ReportCardiothoracic Surgery

Robotic resection of cardiac papillary fibroelastoma guided by three-dimensional transesophageal echocardiography: a case report.

A patient was diagnosed with a papillary fibroelastoma involving the mitral valve. Three-dimensional transesophageal echocardiography (3D TEE) was used to characterize the suspected lesion and assess its anatomy…

Einstein (Sao Paulo)Oct 19, 2026Read case
Clinical ResearchOrthopedic Surgery

Psychological Factors Associated with Function and Health-Related Quality of Life Outcomes following Total Hip or Knee Arthroplasty: An Umbrella Review of Systematic Reviews.

This umbrella review synthesised high-quality evidence from systematic reviews on psychological factors associated with function and health-related quality of life after total hip or knee arthroplasty.

JBJS RevOct 19, 2026Read summary
Clinical ResearchDermatology

Long-term efficacy of lebrikizumab in treating head, neck and face involvement in patients with moderate-to-severe atopic dermatitis.

This post hoc analysis of phase III trials assessed head, neck, and face (HNF) outcomes with lebrikizumab in adolescents and adults with moderate-to-severe atopic dermatitis.

J Dermatolog TreatOct 19, 2026Read summary
Clinical ResearchPsychiatry

Incorporating Data From Text Messages and Email Into Psychotherapy: Randomized Controlled Trial.

This randomized controlled trial examined whether reviewing personalized text-message data before psychotherapy sessions improved outcomes for 101 adults and older adults receiving treatment for primary depression or…

JMIR Ment HealthOct 19, 2026Read summary
Clinical ResearchOphthalmology

Cost-effectiveness of monotherapy and combination therapy for myopia control in Chinese children.

This network meta-analysis and decision-analytic Markov model assessed the cost-effectiveness of 16 myopia-control strategies for Chinese children and adolescents, modelling eight-year-old children over eight years.

J Glob HealthOct 19, 2026Read summary
Clinical ResearchDermatology

Efficacy and safety of subcutaneous efgartigimod with prednisone in moderate-to-severe pemphigus (ADDRESS): a global, phase III, randomised controlled, double-blind trial.

ADDRESS was a global, phase III, multicentre, randomised, double-blind, placebo-controlled trial of adults with newly diagnosed or relapsing moderate-to-severe pemphigus.

Br J DermatolOct 19, 2026Read summary
Clinical ResearchNeurology

Association of dietary choline intake with cognitive decline and related outcomes: a systematic review and dose-response meta-analysis of observational studies.

This systematic review and dose-response meta-analysis examined observational evidence on dietary choline intake and cognitive decline or related outcomes.

Food FunctOct 19, 2026Read summary
Case ReportInfectious DiseasesOpen access

Clinical Recovery Following Conservative Management of a Large Presumed Brain Abscess with a Concomitant Streptococcus intermedius Lung Abscess in a Severely Malnourished Young Adult in a Resource-Limited Setting: A Case Report.

A severely malnourished 22-year-old man presented with progressive left-sided weakness after weeks of productive cough, fever, and weight loss. Examination showed impaired consciousness and flaccid hemiplegia.

Int Med Case Rep JOct 19, 2026Read case
Clinical ResearchEmergency Medicine

Technological Integration in Triage With AI and Machine Learning Compared With Conventional Triage and Narrative Synthesis of Telehealth for Patient Prioritization in Emergency and Acute Care Settings: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed AI- and machine-learning-assisted triage alongside tele-triage and digital tools in emergency and acute care.

J Med Internet ResOct 19, 2026Read summary
Clinical ResearchInfectious Diseases

Evaluating the impact of conditional micro-incentives on linkage to HIV care in rural South Africa: results from the Home-Based Intervention to Test and Start (HITS) trial.

The HITS real-world randomized trial assessed whether conditional food vouchers improved linkage to HIV care after home-based testing in rural KwaZulu-Natal, South Africa.

Health Policy PlanOct 19, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Walnut consumption improves mood and is associated with increased urinary excretion of 5-hydroxyindoleacetic acid and urolithins in a randomized crossover trial.

This 18-week open-label randomized crossover trial assessed whether daily walnut consumption affected mood and urinary metabolites in 31 healthy young adults.

Food FunctOct 19, 2026Read summary
Case ReportRheumatology

SARS-CoV2-induced Schnitzler syndrome, inflammatory flare and successful treatment by anakinra during pregnancy: a case report.

A pregnant woman in her early 40s with established Schnitzler syndrome developed urticaria, musculoskeletal symptoms and elevated inflammatory markers during SARS-CoV-2 infection, consistent with an inflammatory flare.

Swiss Med WklyOct 19, 2026Read case
Clinical ResearchOncology (Medical)Open access

Comparative efficacy of interventions for preventing chemotherapy-induced alopecia: a systematic review and network meta-analysis.

This systematic review and network meta-analysis compared preventive interventions for chemotherapy-induced alopecia in cancer patients, including 12 randomized trials with 736 participants and nine intervention groups.

Support Care CancerOct 19, 2026Read summary
Clinical ResearchEmergency Medicine

POCUS Image Archiving in Emergency Medicine: A Systematic Review of Clinical and Financial Impacts.

This systematic review assessed clinical, operational, and financial outcomes of archiving point-of-care ultrasound (POCUS) images in electronic health records in emergency departments.

Ultrasound QOct 19, 2026Read summary
Clinical ResearchOrthopedic Surgery

Clinical and functional outcomes of aquatic plyometrics in adolescent patellofemoral pain syndrome: a dual-arm randomized controlled trial.

This dual-arm randomized controlled trial compared aquatic plyometric exercises with conventional exercises in 56 adolescents aged 10–18 years with patellofemoral pain syndrome.

J Rehabil MedOct 19, 2026Read summary

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