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751 articles
September 202617
Effects of Pharmacological GIP Infusion on Insulin, Glucagon, and Cardiovascular Responses During Hyperglycemia in Type 2 Diabetes.
This randomized controlled trial investigated the effects of intravenous GIP infusion on glucose homeostasis and cardiovascular responses in ten individuals with type 2 diabetes.
Type 1 Diabetes Driven by Residual Recipient T Cells After Hematopoietic Cell Transplantation: A Case Report.
A patient developed type 1 diabetes following haploidentical hematopoietic cell transplantation. Analysis revealed an expanded population of islet-specific CD4+ T cells in the recipient, predominantly restricted by…
Predicting the Path to Attrition: Multidomain Risk Assessment in Diabetic Foot Ulcer Offloading Randomized Controlled Trials.
This secondary analysis of a 12-week randomized controlled trial examined whether baseline wound, functional, and psychosocial measures predicted attrition among people with diabetic foot ulcers using offloading boots.
Clinical and Biochemical Recovery From Immune Checkpoint Inhibitor-Induced Diabetes With Seroconversion of GAD Antibodies.
A patient with melanoma developed abrupt-onset symptomatic hyperglycemia and mild ketosis after treatment with ipilimumab and nivolumab, indicating immune checkpoint inhibitor-induced diabetes (ICI-D).
Ketone Bodies Derived From Medium-Chain Triglycerides Support Brain Metabolism and Function Under Hypoglycemia in Type 1 Diabetes Mellitus.
This randomized controlled trial investigated the effects of medium-chain triglycerides (MCTs) on brain metabolism during hypoglycemia in individuals with type 1 diabetes mellitus (T1DM).
Real-Time Continuous Glucose Monitoring Among People With Type 2 Diabetes and End-Stage Kidney Failure Undergoing Maintenance Hemodialysis: A Randomized Clinical Trial.
This randomized clinical trial evaluated the effectiveness of real-time continuous glucose monitoring (rtCGM) versus capillary blood glucose (CBG) testing in adults with type 2 diabetes and end-stage kidney failure…
Factors associated with aortic valve calcification in type 2 diabetes-a Steno INTEN-CT substudy.
This cross-sectional substudy of the Steno INTEN-CT trial examined factors linked to aortic valve calcification (AVC) in 4570 individuals with type 2 diabetes (T2D) aged 55-74.
Sensitivity to Endocrine Therapy Index Predicts Benefit from Weekly Adjuvant Paclitaxel for Hormone Receptor-Positive Breast Cancer in the GEICAM/9906 Trial.
This randomized controlled trial evaluated the predictive value of the sensitivity to endocrine therapy (SETER/PR) index for the benefit of weekly adjuvant paclitaxel in hormone receptor-positive breast cancer.
Iron overload disorders in adults: a comprehensive review of gonadal function, reproductive, and sexual health.
This systematic review examined gonadal function, fertility, sexual health, and pregnancy outcomes in adults with iron overload disorders, including thalassaemias, hereditary haemochromatosis, and transfusion-dependent…
Acute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies.
This systematic review evaluated the acute effects of non-oil-seed pulses on cardiometabolic health parameters in humans. It found that 28 of 40 studies reported lower glucose responses and 16 of 24 studies reported…
Dipeptidyl Peptidase-4 Inhibitors Improved Lipid Levels in Patients With Type 2 Diabetes: A Meta-analysis of Randomized Clinical Trials.
This meta-analysis evaluated the effects of dipeptidyl peptidase-4 inhibitors (DPP-4i) on lipid levels in patients with type 2 diabetes (T2D). The analysis included data from 95 randomized controlled trials.
Mediterranean Diet Reduces Inflammation in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the impact of the Mediterranean diet (MD) on inflammation and oxidative stress biomarkers in 3,476 adults across 33 randomized controlled trials.
Biological Pathways of Strength Preservation During Calorie Restriction-Induced Weight Loss Among Adults Without Obesity.
This randomized controlled trial analyzed the CALERIE study to identify molecular predictors of strength preservation during calorie restriction in healthy adults without obesity.
Insulin Efsitora Demonstrates Similar Efficacy and Safety Profiles to Insulin Icodec in Insulin-Experienced Individuals With Type 2 Diabetes Mellitus: Matching-Adjusted Indirect Comparisons of QWINT-3 Versus ONWARDS 2, and QWINT-4 Versus ONWARDS 4.
This matching-adjusted indirect treatment comparison assessed once-weekly insulin efsitora versus insulin icodec in insulin-experienced adults with type 2 diabetes, using data from the randomised QWINT-3 and ONWARDS 2…
Postprandial ultra-fast insulin versus mealtime fast-acting insulin in adults with cystic fibrosis-related diabetes: A randomized multicentre crossover trial.
This open-label, multicentre, randomized phase IV crossover trial compared postprandial ultra-fast-acting insulin (PP-UFI) with standard mealtime fast-acting insulin (MT-FI) in adults with cystic fibrosis-related…
Evaluating Whole Fruit Feijoa Powder for Type 2 Diabetes Risk Prevention: A Randomised Controlled Trial.
This randomised controlled trial tested whether daily whole fruit feijoa powder added to a low energy diet (LED) improved diabetes-risk markers in adults with overweight, predominantly obesity, and prediabetes.
Blood Metabolomic Signatures of 1-Hour Glucose Predict Cardiometabolic Risk.
This study examined whether fasting blood metabolomic signatures associated with 1-hour glucose during an oral glucose tolerance test also track glycemic changes and cardiometabolic risk.
August 20267
Association of tirzepatide with changes in OSA-related measures based on baseline characteristics - post hoc analyses of SURMOUNT-OSA.
This post hoc analysis of two Phase 3 randomized controlled trials evaluated the effects of tirzepatide on obstructive sleep apnea (OSA) measures in adults with moderate-to-severe OSA and obesity.
Calcitonin-negative medullary thyroid carcinoma in a young adult.
A young woman in her early 20s presented with a thyroid nodule and normal serum calcitonin levels, which typically indicate the absence of medullary thyroid carcinoma (MTC).
Dyadic Interventions on Diabetes Self-Management and Glycemic Control for Adults With Type 2 Diabetes: A Systematic Review.
This systematic review evaluated the effectiveness of family-dyad interventions on diabetes self-management and glycemic control in adults with Type 2 diabetes.
Mediterranean diet and metabolic outcomes in nafld/masld: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the effects of the Mediterranean diet on metabolic outcomes in patients with non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction associated steatotic…
Effect of sucrose-free brazzein-sweetened ice cream on continuously monitored glycemic response in patients with metabolic dysfunction-associated steatotic liver disease: A randomized controlled double-blind crossover trial.
This randomized controlled trial evaluated the glycemic response to ice cream sweetened with brazzein, a natural sweet protein, in 101 adults with metabolic dysfunction-associated steatotic liver disease (MASLD).
Glycaemic Changes After Semaglutide Discontinuation in Adults With Type 1 Diabetes Using Automated Insulin Delivery: Analysis of the ADJUST-T1D Extension Study.
This analysis of a 12-week extension to the ADJUST-T1D randomised controlled trial examined continuous glucose monitoring outcomes after semaglutide was stopped in adults with type 1 diabetes and obesity using automated…
Glycemic and safety outcomes of the insulin-only bionic pancreas in older adults and individuals with impaired awareness of Hypoglycemia: a post hoc analysis of a randomized pivotal trial.
This post hoc analysis of a randomized controlled trial evaluated the efficacy and safety of the iLet Bionic Pancreas in 96 older adults and individuals with impaired awareness of hypoglycemia.
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