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785 articles
September 202624
Early Exclusive Enteral Feeding in Preterm Infants: A Meta-Analysis.
This meta-analysis evaluated early exclusive enteral feeding (EEF) versus progressive enteral feeding (PEF) in preterm infants across 11 randomized controlled trials involving 3145 participants.
Liver Fat Changes in Patients With Type 2 Diabetes by Presence of Genetic Hepatic Steatosis: A Post Hoc Analysis of SURPASS-3 MRI.
This post hoc analysis of the SURPASS-3 MRI trial examined the impact of the PNPLA3 I148M genetic variant on liver fat content (LFC) changes in insulin-naïve patients with type 2 diabetes treated with tirzepatide.
Prevalence of Hepatitis B Virus Infection in Cameroon: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed the prevalence of hepatitis B virus (HBV) infection in Cameroon, analyzing 100 studies.
Characterising the Economic Burden of Functional Dyspepsia: A Cost-of-Illness Study of Direct and Indirect Costs.
This randomized controlled trial assessed the economic burden of functional dyspepsia (FD) in 73 patients, focusing on direct and indirect costs.
Novel SLC10A2 variants induce primary bile acid malabsorption and dysbiosis with IBD-like features.
We describe biochemically and functionally validated primary bile acid malabsorption caused by novel biallelic SLC10A2 variants in a child initially diagnosed with Crohn's disease.
Moderate consumption of a polyphenolic-enriched wine attenuates alcohol-associated alterations in hepatic biomarkers in overweight subjects: a randomized clinical trial.
This randomized controlled trial evaluated the effects of a polyphenol-enriched red wine on hepatic biomarkers in overweight adults.
Gastrointestinal Interoception and Relapse in Anorexia Nervosa.
This randomized controlled trial examined gastrointestinal interoception in 62 weight-restored females with anorexia nervosa (AN) compared to 57 healthy controls.
A Phase Ib/IIa Study of Fostrox in Combination with Lenvatinib as Second-line Therapy in Patients with Advanced Hepatocellular Carcinoma.
This multicenter, single-arm Phase Ib/IIa study evaluated the combination of fostroxacitabine bralpamide (fostrox) and lenvatinib in 21 patients with advanced hepatocellular carcinoma (HCC) who progressed on prior…
Ultrasound criteria for transmural healing and response in Crohn's disease: a systematic review of definitions and thresholds.
This systematic review evaluated definitions of transmural healing (TMH) and transmural response (TMR) in Crohn's disease, analyzing 83 studies involving 8033 patients.
The Epidemiology of PRSS1 Hereditary Pancreatitis and Its Clinical Implications: A Systematic Review.
This systematic review examined the epidemiology and clinical implications of PRSS1 hereditary pancreatitis (HP) across 68 studies.
Five-year efficacy and safety of guselkumab for moderately to severely active Crohn's disease: Results from the phase 2 GALAXI 1 trial.
The phase 2 GALAXI 1 trial assessed the long-term efficacy and safety of guselkumab in patients with moderately to severely active Crohn's disease.
Endoscopic Ultrasound-Guided Transluminal Drainage of Walled-Off Necrosis Using Naso-Cystic Drain With Metal Stent Versus Metal Stent Alone: A Randomized Controlled Pilot Study.
This randomized controlled pilot study evaluated the efficacy of endoscopic ultrasound-guided drainage with nasocystic drainage (NCD) versus without NCD in 40 patients with symptomatic walled-off necrosis (WON).
Incidence and predictors of surgical recurrence after primary ileocolic resection in Crohn ileitis: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the incidence and predictors of surgical recurrence after primary ileocolic resection (ICR) in patients with Crohn disease.
The prevalence of abdominal computed tomography imaging findings in patients with inflammatory bowel disease who present to the emergency department: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the prevalence of abdominal CT imaging findings in patients with inflammatory bowel disease (IBD) presenting to the emergency department.
Incidence of acne in patients with inflammatory bowel disease treated with Janus kinase inhibitors: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the incidence of acne in 9902 patients with inflammatory bowel disease (IBD) treated with Janus kinase (JAK) inhibitors.
The Great Imitator: Syphilitic Hepatitis Presenting as a Mimic to Autoimmune Liver Disease.
A 34-year-old male on PrEP for HIV presented with epigastric pain and constitutional symptoms. Laboratory tests showed elevated liver enzymes and positive smooth muscle antibodies, suggesting autoimmune hepatitis.
Acute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies.
This systematic review evaluated the acute effects of non-oil-seed pulses on cardiometabolic health parameters in humans. It found that 28 of 40 studies reported lower glucose responses and 16 of 24 studies reported…
Proficiency in Esophageal Peroral Endoscopic Myotomy: A Meta-Analysis of Learning Curves.
This meta-analysis evaluated the learning curve of peroral endoscopic myotomy (POEM) across 3197 procedures. It found that proficiency in procedure speed was achieved during the 20-40 phase of learning, with mean…
Performance, Efficacy, and Safety of Lubiprostone in Bowel Preparation Regimens: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the efficacy and safety of lubiprostone as an adjunct to bowel preparation for colonoscopy in 1322 patients across eight randomized controlled trials.
Effects of Acute Low- and Moderate-Dose Alcohol on Chronic Disease-Related Biomarkers in Healthy Light and Heavy Drinkers.
This randomized controlled trial examined the effects of low-dose (0.35 g/kg) and moderate-dose (0.60 g/kg) alcohol on disease-related biomarkers in 32 healthy adults, both light and heavy drinkers.
Immune Checkpoint Inhibitor-Induced Pancreatitis.
A case report described five female patients who developed immune checkpoint inhibitor-induced pancreatitis (ICIPI) after receiving combination ICI therapy.
Effect of Age and Age-Defined Menopausal Status on Linaclotide Efficacy and Safety in Adults With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation: Post Hoc Analyses of Phase 2b/3 Studies.
This post hoc analysis of eight randomized, placebo-controlled trials evaluated linaclotide's efficacy and safety in adults with irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation…
Impact of evidence-based feeding protocols on clinical outcomes and nutritional delivery in critically ill adults: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of evidence-based feeding protocols on clinical outcomes and nutritional delivery in critically ill adults.
Systematic review and meta-analysis on key controversies in the management of diverticular disease: a multi-society collaboration.
This systematic review and meta-analysis evaluated the management of diverticular disease, focusing on symptomatic uncomplicated diverticular disease (SUDD), uncomplicated diverticulitis, and complicated diverticulitis.
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