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751 articles
August 202624
Food intake sequence affects postprandial metabolic, hormonal, and appetite responses in healthy male football players: A randomised crossover trial.
This randomized crossover trial examined the effects of food intake sequence on postprandial responses in 14 highly trained male football players.
Dulaglutide vs insulin in adolescents with thalassaemia-induced diabetes: effect on metabolism and atherogenesis (DIADEMA).
The DIADEMA trial compared dulaglutide to insulin in adolescents (10-18 years) with thalassaemia-induced diabetes. After 24 weeks, dulaglutide significantly reduced glycaemic variability (CV decreased from 39.45% to…
Aldosterone-renin ratio and plasma renin activity as biomarkers for treatment response in resistant hypertension.
This post hoc analysis of a randomized controlled trial assessed the relationship between baseline aldosterone-renin ratio (ARR) and plasma renin activity (PRA) with treatment response in 114 patients with resistant…
Effects of Vascular Photobiomodulation on Glycemic Control in Patients With Type II Diabetes Mellitus: A Prospective Single-Arm Clinical Study.
This prospective, single-arm clinical study evaluated vascular photobiomodulation (VPBM) alongside ongoing metformin therapy in people with type 2 diabetes.
Targeted Assessment in High-Risk Patients With Diabetes to Identify Undiagnosed Heart Failure (TARTAN-HF).
TARTAN-HF was a prospective, multicenter, unblinded randomized controlled trial of community-based adults aged ≥40 years with type 1 or type 2 diabetes, at least one additional heart failure (HF) risk factor, and no…
Technology choice, glycemic control and patient-reported outcome measures in adults with type 1 diabetes: A randomized crossover trial comparing a smart insulin pen with an automated insulin delivery system (EBIACE-1).
This randomized crossover trial evaluated glycemic outcomes and patient-reported outcomes in 31 adults with type 1 diabetes using a smart insulin pen (SIP) versus an automated insulin delivery (AID) system.
Neuromuscular electrical stimulation protocols for glycaemic control in adults with type 2 diabetes mellitus: a systematic review.
This systematic review evaluated the effects of neuromuscular electrical stimulation (NMES) on glycaemic control in adults with type 2 diabetes mellitus (T2DM).
Effect of Semaglutide on the Inflammatory Biomarker High-Sensitivity CRP in Patients With Established Cardiovascular Disease and Overweight or Obesity in SELECT: A Prespecified Secondary Analysis.
This prespecified secondary analysis of the SELECT trial evaluated the impact of semaglutide on high-sensitivity C-reactive protein (hsCRP) levels in 17,604 patients with established cardiovascular disease and obesity.
A multi-centre study of belatacept and sirolimus for islet transplantation.
This phase II, multi-centre clinical trial evaluated the efficacy of belatacept and sirolimus (bela/siro) in islet transplantation for type 1 diabetes.
The effectiveness of digital health interventions for type 2 diabetes in underserved populations: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of digital health interventions (DHIs) on glycemic control in underserved adults with type 2 diabetes across 12 randomized controlled trials involving 1835…
Long-term safety of oral orforglipron in Japanese participants with type 2 diabetes (ACHIEVE-J): a multicentre, randomised, open-label, parallel-group phase 3 trial.
This multicentre, randomised, open-label phase 3 trial evaluated the long-term safety of oral orforglipron in Japanese adults with type 2 diabetes.
Vegetable-First Meal Sequence Suppresses Postprandial Glycaemic Excursions and Variability in Young Women With High-Risk Phenotype for Early-Onset Type 2 Diabetes: A 4-Arm Randomized Crossover Trial With Continuous Glucose Monitoring.
This randomized crossover trial assessed whether meal order affects glucose profiles in 33 healthy Korean women, using continuous glucose monitoring after three days of repeated interventions.
Body Composition Remodelling During GLP-1-Based Therapy: A Systematic Review and Meta-Analysis Using a Hierarchical Physiological Framework.
This systematic review and meta-analysis assessed longitudinal changes in body composition during GLP-1 receptor agonist or dual incretin therapy in adults.
Retatrutide-Associated Improvements in Cardiovascular Risk Biomarkers in Adults With Obesity With or Without Type 2 Diabetes.
This post hoc analysis of two randomised, double-blind, placebo-controlled phase 2 trials assessed lipoprotein and inflammatory biomarkers in adults with overweight or obesity, with or without type 2 diabetes, treated…
Oleanolic Acid-Enriched Olive Oil Attenuates Kidney Function Decline in Patients With Type 2 Diabetes: Results From the OLTRAD Randomised Controlled Trial.
This prespecified, exploratory secondary analysis of the OLTRAD randomised controlled trial assessed kidney outcomes in 97 patients with type 2 diabetes assigned to oleanolic acid (OA)-enriched or control olive oil for…
Efficacy of Luseogliflozin Added to Semaglutide in Patients With Metabolic Dysfunction-Associated Steatohepatitis and Type 2 Diabetes Mellitus: A Randomised, Open-Label Trial.
This 52-week, open-label, randomised, parallel-group trial in Japan compared luseogliflozin plus semaglutide with semaglutide alone in adults with biopsy-proven MASH and type 2 diabetes.
Fatty Liver Index and Differential Glycemic Responses to Ipragliflozin Versus Sitagliptin Over 52 Weeks: An Exploratory Post Hoc Analysis of the Niigata Ipragliflozin and Sitagliptin With Metformin (N-ISM) Study.
This exploratory post hoc analysis of a 52-week randomised trial examined whether fatty liver index (FLI) was associated with different glycemic responses to ipragliflozin versus sitagliptin added to metformin in…
Association between thyroid peroxidase antibody positivity and the risk of perinatal depression: a meta-analysis.
This meta-analysis assessed whether thyroid peroxidase antibody (TPOAb) positivity is associated with perinatal depression (PND), combining cohort, case-control, and cross-sectional studies.
Three Generations of X-Linked Hypophosphataemia: The Inter-generational Impact of Burosumab Across the Lifespan.
This case report describes three generations of a family affected by X-linked hypophosphataemia (XLH), each receiving burosumab therapy at different life stages.
Effect of a 6-month low-carbohydrate diet on the circulating fatty acid composition in patients with type 2 diabetes: a secondary analysis of an open-label randomized controlled trial.
This open-label randomized controlled trial investigated the effects of a 6-month low-carbohydrate diet (LCD) on circulating fatty acid composition in 71 adults with type 2 diabetes.
Molecular stability overrides size in giant pediatric pheochromocytoma.
A 16-year-old female presented with severe hypertension and hyperglycemia, initially misdiagnosed with essential hypertension and type 2 diabetes.
Glycaemic variation and atrial fibrillation burden and progression in individuals without diabetes undergoing continuous rhythm monitoring.
This randomized controlled trial analyzed 884 participants without diabetes from the LOOP Study to assess the relationship between glycaemic variation and atrial fibrillation (AF) burden.
Comparing efficacy in glycaemic control and pregnancy outcomes between continuous glucose monitoring and self-monitoring of blood glucose in pregnancies complicated by gestational diabetes mellitus: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of continuous glucose monitoring (CGM) versus self-monitoring of blood glucose (SMBG) in 5,650 pregnant women with gestational diabetes mellitus (GDM).
Neonatal Hyperthyroidism: Case Report and Literature Review.
A late preterm infant presented with thyrotoxicosis due to maternal Graves disease, which had been treated with radioactive iodine.
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