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406 articles
June 202624
Barriers and facilitators to detoxification from opioid substitution treatment: A mixed-methods systematic review.
This mixed-methods systematic review examined barriers and facilitators to detoxification from opioid substitution treatment (OST) in individuals with opioid dependence.
The relationship between subjective (arousal and craving) and physiological (heart rate variability) stress- and alcohol cue-reactivity in young adults who engaged in hazardous drinking: a counterbalanced study.
This randomized controlled trial investigated the effects of stress and alcohol cues on craving and heart rate variability (HRV) in 56 young adults with hazardous drinking.
Effect of partial replacement of animal protein with plant protein on glycemic control in type 2 diabetes: Rationale, design, and protocol of a randomized clinical trial.
This randomized clinical trial investigates the impact of a plant-based diet with partial animal protein replacement on glycemic control in adults with type 2 diabetes and overweight/obesity.
Environmental Burden of Lead and Public Health Issues in Nigeria: A Systematic Review of Emerging Evidence.
This systematic review examined the environmental burden of lead exposure in Nigeria, highlighting severe contamination in artisanal mining areas and urban centers.
Early versus late oral anticoagulants after acute ischemic stroke in atrial fibrillation patients: a meta-analysis of randomized controlled trials.
This meta-analysis of randomized controlled trials evaluated the timing of oral anticoagulant (OAC) initiation in patients with atrial fibrillation (AF) after acute ischemic stroke.
Accuracy and precision of continuous, non-invasive blood pressure devices: a systematic review and meta-analyses.
This systematic review and six meta-analyses assessed continuous non-invasive blood pressure technologies against invasive arterial measurements in adults, using data from 65 studies.
Sero-Diagnosis of Scrub Typhus Infection in India: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the prevalence of scrub typhus among patients with acute febrile illness in India.
When the test lies: Fatal cryptococcosis and the prozone effect in advanced HIV infection.
A 37-year-old man with advanced HIV infection presented with altered mental status. Initial cryptococcal antigen (CrAg) tests on serum and cerebrospinal fluid (CSF) were negative.
The state urge to be physically active in anorexia nervosa: a systematic review of mechanisms and clinical implications.
This systematic review examined the State Urge to be Physically Active (SUPA) in individuals with anorexia nervosa (AN), analyzing 17 studies.
Stress ulcer prophylaxis in mechanically ventilated patients.
This meta-analysis evaluated the efficacy of proton pump inhibitors (PPI) versus histamine 2 receptor antagonists (H2RA) and placebo for upper gastrointestinal bleeding (UGIB) prophylaxis in mechanically ventilated…
Factors associated with the percentage of individuals who initiate and discontinue naltrexone as a relapse prevention pharmacotherapy in opioid use disorder: A systematic review, meta-analysis and meta-regression.
This systematic review and meta-analysis examined initiation and discontinuation rates of naltrexone for relapse prevention in opioid use disorder (OUD) among 124,016 individuals.
Impact of Different Exercise Modalities on Visceral Adipose Tissue in Normal Weight and Low-Overweight Individuals: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the impact of various exercise modalities on visceral adipose tissue (VAT) in adults with a BMI ≤27 kg/m².
Sodium Bicarbonate for Critically Ill Adults with Metabolic Acidosis and Shock.
This randomized controlled trial evaluated the effects of sodium bicarbonate in 500 critically ill adults with metabolic acidosis receiving vasopressors.
Risks Associated With Benzodiazepine Long-Term Use in Chronic Insomnia: A Systematic Review and (Network) Meta-Analysis.
This systematic review and meta-analysis evaluated the risks of long-term benzodiazepine use in adults with chronic insomnia, analyzing 27 studies.
Efficacy of lemborexant on sleep quality and neurocognitive outcomes among hospital rotating shift workers: A randomized, double-blind, placebo-controlled trial.
This randomized, double-blind, placebo-controlled trial evaluated the effects of lemborexant 5 mg on sleep quality and neurocognitive outcomes in rotating shift workers aged 20 to 60 years.
Efficacy and Safety Profile of a Triple Single-Pill Combination of Valsartan/Amlodipine/Chlorthalidone in Patients with Uncontrolled Hypertension.
This randomized, double-blind, multicenter Phase III trial assessed the efficacy and safety of a single-pill combination of valsartan/amlodipine/chlorthalidone in 294 patients with uncontrolled hypertension.
Effectiveness of oral care for the prevention of non-ventilator hospital-acquired pneumonia (HAPPEN): a multicentre, stepped-wedge, cluster-randomised trial in Australia.
The HAPPEN trial, a multicentre, stepped-wedge, cluster-randomised trial in Australia, evaluated the impact of enhanced oral care on non-ventilator hospital-acquired pneumonia (NV-HAP) incidence among hospitalized…
A GRADE-assessed systematic review and meta-analysis of randomized controlled trials evaluating the effects of olive leaf or olive pomace supplementation on cardiometabolic and anthropometric health markers.
This systematic review and meta-analysis evaluated the effects of olive leaf (OL) and olive pomace (OP) supplementation on cardiometabolic health in 1726 participants across 30 randomized controlled trials.
Body mass index and baricitinib treatment effect in hospitalized adults with COVID-19: A secondary analysis of ACTT-2.
This secondary analysis of the ACTT-2 randomized controlled trial evaluated the impact of body mass index (BMI) on the efficacy of baricitinib in hospitalized COVID-19 patients.
Digital health self-management support for stroke patients following discharge: A randomized controlled trial.
This randomized controlled trial evaluated a digital self-management support program for 183 stroke patients post-discharge in China.
Early-event pathways to 6-month death or dependency after ischemic stroke: Secondary analysis of the international stroke trial.
This secondary analysis of the International Stroke Trial examined early-event pathways to 6-month death or dependency in 19,285 ischemic stroke patients.
Resistance training and diabetes mellitus type 2: An umbrella review of systematic reviews and meta-analyses on glycemic and cardiometabolic outcomes.
This umbrella review assessed the effects of resistance training (RT) on glycemic and cardiometabolic outcomes in adults with type 2 diabetes (T2D) by analyzing 43 systematic reviews and meta-analyses.
Incidence and risk factors of sepsis-associated delirium in the intensive care unit: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the incidence and risk factors of sepsis-associated delirium (SAD) in ICU patients, analyzing data from 52 studies with 89,789 patients.
Obexelimab for the Treatment of IgG4-Related Disease.
This phase 3 randomized controlled trial evaluated obexelimab in 194 patients with active IgG4-related disease. The study found that obexelimab significantly prolonged the time to the first disease flare requiring…
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