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1821 articles
September 202624
Unusual pelvic mass in a young adult: prostatic Ewing's sarcoma with distant metastases.
A man in his 20s presented with urinary obstruction, constipation, and leg pain. Imaging revealed a bulky pelvic mass from the prostate, leading to bilateral hydroureteronephrosis.
Pure Red Cell Aplasia Following Neoadjuvant Docetaxel/Carboplatin/Trastuzumab (TCbH) in a 45‑Year‑Old Woman With Breast Cancer Successfully Treated With Cyclosporine.
A 45-year-old woman with HER2-positive breast cancer developed pure red cell aplasia (PRCA) after neoadjuvant treatment with docetaxel/carboplatin/trastuzumab.
Fasting-induced metabolic reprogramming as a therapeutic vulnerability in cancer: a systematic mechanistic review of in vitro evidence.
This systematic review evaluated in vitro studies on fasting and fasting-mimicking interventions in cancer cell models. It found that fasting consistently reduced IGF-1 signaling and inhibited key metabolic pathways…
ATM mutations in myelodysplastic neoplasms, acute myeloid leukemia, and myeloproliferative neoplasms: a systematic review.
This systematic review evaluated the impact of ATM mutations in myelodysplastic neoplasms (MDS), acute myeloid leukemia (AML), and myeloproliferative neoplasms (MPN).
Meaning-centered psychotherapy for existential distress in advanced cancer: A culturally informed case report from Vietnam.
A 24-year-old Vietnamese woman with advanced cancer presented with severe depressive symptoms, emotional instability, and passive wishes for death.
Fourteen-Year Course of Multiple Recurrent and Distantly Metastatic Hepatic Epithelioid Hemangioendothelioma With Serial Ki-67 Evolution: A Case Report.
A 48-year-old woman with hepatic epithelioid hemangioendothelioma (HEHE) underwent right partial hepatectomy after a liver lesion was found incidentally. Histological analysis confirmed the diagnosis.
A case report on the management of sepsis complicated by eroded mixed hemorrhoids following breast cancer chemotherapy.
A 51-year-old female with stage IIIA breast cancer developed septicemia and eroded mixed hemorrhoids following chemotherapy. She presented with severe neutropenia and a high fever.
Mucinous adenocarcinoma presenting as adult colonic intussusception: A case report.
A 75-year-old woman with multiple comorbidities presented with hematochezia, abdominal distension, intermittent colicky pain, and weight loss.
Vision loss as the first manifestation of isolated cns relapse in CML blast crisis during flumatinib maintenance therapy: A case report.
A 65-year-old male with chronic myeloid leukemia in complete remission presented with progressive vision loss, indicating isolated CNS relapse.
Electronic patient-reported outcome platforms used in hematological cancers: a systematic review.
This systematic review examined electronic patient-reported outcome measures (ePROMs) in hematological cancers, identifying 14 platforms from 18 studies.
Intratumoral and Peritumoral Features for Predicting Microvascular Invasion in Hepatocellular Carcinoma: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed the effectiveness of radiomics-based models in predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC).
Radiotherapy versus observation following surgical resection of WHO grade 2 atypical meningioma (ROAM/EORTC-1308): an international, multicentre, open-label, phase 3, randomised controlled trial.
ROAM/EORTC-1308 was an international, multicentre, open-label, phase 3 randomised trial comparing adjuvant radiotherapy with observation after complete resection of newly diagnosed WHO grade 2 atypical meningioma.
Evaluating the Impact of CYP1A2 Inhibition on the Pharmacokinetics of Savolitinib: A Phase 1 Open-Label Study.
This Phase 1 open-label study assessed the effects of CYP1A2 inhibition by fluvoxamine on the pharmacokinetics of savolitinib in 16 healthy male volunteers.
Phase 1 Study of Anito-cel, a d-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma.
This phase 1 multicenter study evaluated the safety and efficacy of anitocabtagene autoleucel (anito-cel), a BCMA-directed CAR T-cell therapy, in 40 patients with relapsed or refractory multiple myeloma.
Immune Checkpoint Inhibition in Locally Advanced Periocular Squamous Cell Carcinoma (POLA-SCC).
A 75-year-old man presented with recurrent upper eyelid squamous cell carcinoma (SCC) that persisted despite multiple surgical excisions and reconstructive efforts, leading to significant eyelid dysfunction and visual…
Primary Orbital Melanoma: A Systematic Review of Clinical Characteristics, Management and Outcomes.
This systematic review evaluated clinical characteristics, management, and outcomes of 112 patients with histopathologically confirmed primary orbital melanoma (POM).
AdvanTIG-105: a phase I/Ib dose-expansion study of ociperlimab plus tislelizumab with or without chemotherapy in metastatic non-small cell lung cancer and extensive-stage small cell lung cancer.
The AdvanTIG-105 study evaluated the combination of ociperlimab and tislelizumab, with or without chemotherapy, in patients with metastatic non-small cell lung cancer (NSCLC) and extensive-stage small cell lung cancer…
Jejunal metastatic melanoma presenting with occult gastrointestinal haemorrhage and refractory anaemia.
An elderly man with a history of cutaneous melanoma presented with chronic iron-deficiency anemia and weight loss. Imaging and endoscopy failed to provide a definitive diagnosis, revealing only an aneurysmal jejunal…
Renal synovial sarcoma occurring synchronously with renal cell carcinoma.
A patient in his 50s presented with abdominal pain and hematuria, leading to the discovery of a primary biphasic synovial sarcoma of the kidney alongside synchronous clear cell renal cell carcinoma.
When immunotherapy mimics pancreatic cancer: mass-forming immune-related pancreatitis during neoadjuvant treatment for triple-negative breast cancer.
A woman with early triple-negative breast cancer developed four hypermetabolic pancreatic lesions after 4 months of neoadjuvant chemoimmunotherapy, initially suggestive of metastases.
Anaphylaxis to both pegfilgrastim and sargramostim in a patient with diffuse large B-cell lymphoma.
A woman in her early 60s with stage 3A diffuse large B-cell lymphoma experienced anaphylaxis to pegfilgrastim after her first cycle of R-CHOP chemotherapy, presenting with syncope and severe hypotension.
Classic mantle cell lymphoma with aberrant immunohistochemical expression of Fc receptor-like 4/immunoglobulin superfamily receptor translocation-associated 1.
A patient diagnosed with classic mantle cell lymphoma (MCL) presented with typical clinical, morphologic, immunophenotypic, and genetic features.
Kaposiform haemangioendothelioma presentation in hand in a paediatric patient.
A young female patient presented with progressive swelling and discoloration of the pulp of her right middle finger. Initially misdiagnosed as chronic osteomyelitis, further evaluation confirmed the diagnosis of…
Prognostic Value of the C-Reactive Protein-Albumin-Lymphocyte Index in Hepatobiliary and Pancreatic Cancers: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the prognostic value of the C-reactive protein-albumin-lymphocyte (CALLY) index in patients with hepatobiliary and pancreatic cancers.
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