Trending archive
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947 articles
September 20265
Acute Effects of Non-Oil-Seed Pulses on Parameters of Cardiometabolic Health: A Systematic Review of Human Intervention Studies.
This systematic review evaluated the acute effects of non-oil-seed pulses on cardiometabolic health parameters in humans. It found that 28 of 40 studies reported lower glucose responses and 16 of 24 studies reported…
Association Between Changes in Salt Intake and Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the relationship between salt intake and blood pressure across 43 randomized controlled trials.
Interventions to Reduce Sodium Consumption Through a Reduction in Salt Usage in Cooking-A Systematic Review and Meta-analysis.
This systematic review and meta-analysis evaluated interventions aimed at reducing salt usage in cooking among adults. The analysis included 13 studies, revealing a significant trend towards reduced sodium intake, with…
Mediterranean Diet Reduces Inflammation in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the impact of the Mediterranean diet (MD) on inflammation and oxidative stress biomarkers in 3,476 adults across 33 randomized controlled trials.
Blood Metabolomic Signatures of 1-Hour Glucose Predict Cardiometabolic Risk.
This study examined whether fasting blood metabolomic signatures associated with 1-hour glucose during an oral glucose tolerance test also track glycemic changes and cardiometabolic risk.
August 202619
Prognostic significance of stress hyperglycemia ratio in patients undergoing percutaneous coronary intervention: a dose-response meta-analysis.
This meta-analysis evaluated the prognostic significance of the stress hyperglycemia ratio (SHR) in 41,096 patients undergoing percutaneous coronary intervention (PCI).
Effect of Wearable Devices and 5G-Powered Remote Precision Rehabilitation on Vascular Function in Post-PCI Patients: An Analysis of the Associations Between FMS, Cardiorespiratory Fitness, and Arterial Stiffness.
This randomized controlled trial investigated the impact of 5G-powered remote rehabilitation on vascular function in 155 post-PCI patients.
Targeted left ventricular lead placement in biventricular pacing for heart failure: a national, multicentre, double-blind, randomised controlled trial in Denmark.
This multicentre, double-blind, randomised controlled trial evaluated the impact of targeted left ventricular lead placement at the site of latest electrical activation on heart failure outcomes in 1000 patients.
Subcentimeter Ileal Neuroendocrine Tumor Resection for Obscure Gastrointestinal Bleeding Followed by Pacemaker-Treated Sick Sinus Syndrome: A Case Report.
A 72-year-old man presented with melena and abdominal discomfort, with prior endoscopies yielding no diagnosis. Multiphase computed tomographic enterography identified an 11×8 mm enhancing nodule in the distal small…
Effect of Vutrisiran According to Baseline Tafamidis Use in Transthyretin Amyloidosis With Cardiomyopathy: Insights From HELIOS-B.
This randomized controlled trial evaluated the effects of vutrisiran in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM), stratified by baseline tafamidis use.
Influence of Disease-Modifying Therapy on the Efficacy of Vutrisiran in Transthyretin Cardiac Amyloidosis.
This randomized controlled trial evaluated the impact of concomitant disease-modifying therapies on the efficacy of vutrisiran in 654 patients with transthyretin amyloid cardiomyopathy (ATTR-CM).
A First-in-Human Study of Ulacamten, a Novel Cardiac Myosin Inhibitor for HFpEF.
This phase I randomized controlled trial evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ulacamten, a cardiac myosin inhibitor, in healthy adults.
Tricuspid-Valve Intervention in Heart Failure.
This multicenter randomized trial compared transcatheter tricuspid-valve repair plus medical therapy with medical therapy alone in 360 patients with symptomatic severe tricuspid regurgitation and increased risk of…
Natriuretic Peptide and Transthyretin and Their Relationship With Clinical Outcomes: Results From ATTRIBUTE-CM, a Randomized Controlled Trial.
This post hoc biomarker analysis of ATTRIBUTE-CM, a phase 3 randomized, double-blind, placebo-controlled trial, examined baseline NT-proBNP and serum transthyretin (sTTR) in 632 participants with transthyretin amyloid…
Comparative Effectiveness of Chlorthalidone Versus Hydrochlorothiazide and Dose-Response of Amiloride on Blood Pressure and Biochemical Parameters.
This 12-week factorial randomized clinical trial compared chlorthalidone 25 mg with hydrochlorothiazide 50 mg, and amiloride 5 mg with 10 mg, assessing office and ambulatory blood pressure and laboratory parameters.
Effects of semaglutide and empagliflozin on markers of endothelial function in persons with type 2 diabetes: A post hoc analysis of a randomized clinical trial.
This post-hoc analysis of a 32-week randomized trial evaluated the effects of semaglutide and empagliflozin on endothelial function markers in 120 participants with type 2 diabetes.
Prothrombin complex concentrate (PCC) vs. non-PCC strategies for warfarin reversal in left ventricular assist device recipients: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated prothrombin complex concentrate (PCC) versus non-PCC strategies for warfarin reversal in left ventricular assist device (LVAD) recipients.
Complete Revascularization Guided by Functional Coronary Angiography in STEMI.
This randomized controlled trial evaluated the effectiveness of complete coronary-artery revascularization guided by functional coronary angiography versus conventional angiography in patients with STEMI and multivessel…
Effects of acute and short-term grape seed extract supplementation on blood pressure responses to exercise in individuals at cardiometabolic risk: A randomised, double-blind, placebo-controlled exploratory crossover trial.
This randomized, double-blind, placebo-controlled crossover trial examined the effects of grape seed extract (GSE) supplementation on blood pressure responses to exercise in ten sedentary adults with elevated blood…
Atorvastatin, Cardiovascular Events, and Disability-free Survival in Older Adults.
This randomized controlled trial evaluated the effects of atorvastatin on cardiovascular events and disability-free survival in 9971 community-dwelling adults aged 70 and older without prior cardiovascular disease.
Effect of Aficamten on Cardiac Structure and Function in Patients With Symptomatic Nonobstructive Hypertrophic Cardiomyopathy.
This prespecified exploratory analysis of the phase 3, multicentre, randomised, placebo-controlled ACACIA-HCM trial examined serial echocardiographic changes in symptomatic patients with nonobstructive hypertrophic…
Milvexian with Antiplatelet Therapy after Acute Coronary Syndrome Event.
This phase 3, multicentre, randomised, placebo-controlled trial tested milvexian added to standard antiplatelet therapy in patients treated within 7 days after an acute coronary syndrome event.
Safety and lipoprotein(a)-lowering effects of Kylo-11, a non-canonical, long-duration small interfering RNA targeting lipoprotein(a): a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial.
This phase 1, randomized, double-blind, placebo-controlled trial evaluated the safety and lipoprotein(a)-lowering effects of Kylo-11 in 71 healthy adults aged 18-55 with elevated lipoprotein(a).
Bivalirudin Versus Heparin in Low and Non-Low Bleeding Risk Patients Undergoing Primary PCI for STEMI: The BRIGHT-4 Trial.
The BRIGHT-4 trial, a randomized controlled trial involving 6,016 STEMI patients undergoing primary PCI, compared bivalirudin with heparin.
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