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785 articles

August 202624

Clinical ResearchGastroenterology

Meta-Analysis: Enhanced Liver Fibrosis (ELF) Test for Identifying Significant Fibrosis, Advanced Fibrosis, and Cirrhosis in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease.

This meta-analysis evaluated the Enhanced Liver Fibrosis (ELF) test for identifying significant fibrosis (≥F2), advanced fibrosis (≥F3), and cirrhosis (F4) in patients with metabolic dysfunction-associated steatotic…

Aliment Pharmacol TherAug 24, 2026Read summary
Clinical ResearchGastroenterology

Yukgunja-tang and Pyeongwi-san improve functional dyspepsia and modulate ghrelin dynamics: A multicenter randomized controlled trial.

This multicenter, assessor-blind randomized controlled trial compared Yukgunja-tang (YGJ) and Pyeongwi-san (PWS) with usual care (UC) in 140 patients with functional dyspepsia treated for 6 weeks.

J EthnopharmacolAug 24, 2026Read summary
Clinical ResearchOncology (Medical)

Chemoradiotherapy versus short-course radiotherapy for response-adapted organ preservation in early-stage and intermediate-stage rectal cancer (STAR-TREC): 12-month results of an international, multicentre, open-label, parallel-group, randomised, phase 2/3 trial.

The STAR-TREC trial evaluated long-course chemoradiotherapy (LCCRT) versus short-course radiotherapy (SCRT) for organ preservation in early-stage and intermediate-stage rectal cancer.

Lancet OncolAug 23, 2026Read summary
Clinical ResearchGastroenterology

Optimization of Minocycline-Containing Bismuth Quadruple Therapy for Helicobacter pylori Rescue Treatment: A Randomized Controlled Trial.

This randomized controlled trial evaluated the efficacy and safety of minocycline-containing bismuth quadruple therapy for Helicobacter pylori rescue treatment in 480 refractory patients.

J Gastroenterol HepatolAug 23, 2026Read summary
Clinical ResearchOncology (Medical)

Older adults with resectable gastric cancer undergoing perioperative chemotherapy or preoperative chemoradiotherapy plus perioperative chemotherapy: A secondary analysis of the AGITG TOPGEAR phase III trial.

This secondary analysis of the AGITG TOPGEAR phase III trial evaluated older adults (≥70 years) with resectable gastric cancer undergoing perioperative chemotherapy or chemoradiotherapy.

Eur J CancerAug 22, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Pharmacokinetics of IL-23p19 Inhibitors: A Systematic Review Across Immune-Mediated Inflammatory Diseases.

This systematic review evaluated the pharmacokinetics of IL-23p19 inhibitors across various immune-mediated inflammatory diseases, including inflammatory bowel disease (IBD).

Clin PharmacokinetAug 22, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Self-Directed Mikoto Simulator Training for Colonoscopy in Gastroenterology Trainees: An International Multicenter Randomized Trial.

This multicenter randomized trial evaluated the impact of self-directed mikoto simulator training on colonoscopy insertion performance among 12 gastroenterology trainees across Japan and Taiwan.

J Gastroenterol HepatolAug 21, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Long-term microbiome and clinical effects of a microbiome-guided personalized diet versus low-FODMAP diet in irritable bowel syndrome: A 12-month follow-up randomized controlled trial.

This multicenter randomized controlled trial evaluated the long-term effects of a microbiome-guided personalized diet (PD) versus a low-FODMAP diet (LFD) in adults with irritable bowel syndrome (IBS).

Gut MicrobesAug 20, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Effects of diabetes, obesity, and metabolic syndrome on alcohol-associated liver disease: A systematic review.

This systematic review evaluated the impact of cardiometabolic risk factors (CMRFs) on clinical outcomes in adults with alcohol-associated liver disease (ALD).

Hepatol CommunAug 20, 2026Read summary
Clinical ResearchGastroenterology

Hepatotoxicity of OBS: A review of the emerging PFOS substitute.

This systematic review evaluates the hepatotoxic effects of sodium perfluorononenyl oxobenzene sulfonate (OBS), an alternative to PFOS, across various studies.

Toxicol LettAug 19, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Efficacy, Safety, and Pharmacokinetics of Upadacitinib Among Patients in East Asia With Moderately to Severely Active Ulcerative Colitis: A Post Hoc Subanalysis of Randomized Phase 3 Studies.

This post hoc subanalysis of Phase 3 randomized trials evaluated the efficacy, safety, and pharmacokinetics of upadacitinib in East Asian patients with moderately to severely active ulcerative colitis.

J Gastroenterol HepatolAug 19, 2026Read summary
Clinical ResearchEndocrinology

Food intake sequence affects postprandial metabolic, hormonal, and appetite responses in healthy male football players: A randomised crossover trial.

This randomized crossover trial examined the effects of food intake sequence on postprandial responses in 14 highly trained male football players.

Clin Nutr ESPENAug 19, 2026Read summary
Clinical ResearchGastroenterology

Influence of artificial intelligence on the performance of endosonographers in detection of solid pancreatic tumors: a tandem randomized video study.

This randomized controlled trial evaluated the impact of an AI-based software system on endosonographers' performance in detecting solid pancreatic tumors (SPTs) using curated EUS videos.

EndoscopyAug 19, 2026Read summary
Clinical ResearchGastroenterology

Evaluating surgical management of primary achalasia-a systematic review and network meta-analysis of randomized clinical trials.

This systematic review and network meta-analysis evaluated the outcomes of various surgical interventions for primary achalasia in 1170 patients across 15 randomized clinical trials.

J Gastrointest SurgAug 19, 2026Read summary
Case ReportGastroenterology

Delayed Esophageal Perforation With Esophagomediastinal Fistula and Mediastinal Abscess Mimicking Malignancy on 18 F-FDG PET/CT After Hard Fish Chunk Impaction.

A 74-year-old woman with a pulmonary nodule showing interval growth on follow-up imaging presented with dysphagia and abdominal bloating.

Clin Nucl MedAug 19, 2026Read case
Case ReportOncology (Medical)

Cutibacterium avidum caused a liver abscess after transarterial chemoembolization for hepatocellular carcinoma.

An 83-year-old man developed a liver abscess following transarterial chemoembolization for recurrent hepatocellular carcinoma, presenting with fever 10 days post-procedure.

J Infect ChemotherAug 18, 2026Read case
Clinical ResearchGastroenterologyOpen access

Hemostatic Efficacy and Safety of the Hybrid Injector ClearCoajet in Endoscopic Mucosal Resection of Large Colorectal Polyps: A Multicenter Randomized Trial.

This multicenter randomized trial evaluated the hemostatic efficacy and safety of the ClearCoajet device during endoscopic mucosal resection of large colorectal polyps in 220 patients.

Dig Dis SciAug 18, 2026Read summary
Clinical ResearchGastroenterology

Consolidation Therapy of Probiotics With Rifaximin Prevent Relapse in Rifaximin-Responsive Diarrhea-Predominant Irritable Bowel Syndrome: A Multicenter Randomized Clinical Trial.

This multicenter randomized clinical trial evaluated the effectiveness of consolidation therapy with Medilac-S probiotics following rifaximin treatment in patients with diarrhea-predominant irritable bowel syndrome…

J Gastroenterol HepatolAug 18, 2026Read summary
Clinical ResearchEndocrinology

Efficacy of Luseogliflozin Added to Semaglutide in Patients With Metabolic Dysfunction-Associated Steatohepatitis and Type 2 Diabetes Mellitus: A Randomised, Open-Label Trial.

This 52-week, open-label, randomised, parallel-group trial in Japan compared luseogliflozin plus semaglutide with semaglutide alone in adults with biopsy-proven MASH and type 2 diabetes.

Diabetes Obes MetabAug 17, 2026Read summary
Clinical ResearchGastroenterology

Effectiveness of multitarget stool DNA versus faecal immunochemical testing alone in detecting colorectal cancer and advanced polyps: A systematic review.

This systematic review evaluated the effectiveness of multitarget stool DNA (mt-sDNA) compared to faecal immunochemical testing (FIT) for detecting colorectal cancer (CRC) and advanced polyps.

Cancer EpidemiolAug 14, 2026Read summary
Clinical ResearchGeneral Surgery

Defining Clinically Significant Radiographic Recurrence after Paraesophageal Hernia Repair: Post Hoc Analysis of Patient-Reported Outcomes and Reoperation from a Randomized Controlled Trial.

This post hoc analysis of a randomized controlled trial evaluated the correlation between radiographic recurrence size and reoperation rates as well as patient-reported outcomes in adults undergoing minimally invasive…

J Am Coll SurgAug 14, 2026Read summary
Clinical ResearchGastroenterology

Efficacy of probiotic and synbiotic supplementation on antibiotic use duration and risk of postoperative infection in patients undergoing gastrointestinal and cancer-related surgery: An umbrella review of meta-analyses.

This umbrella review assessed the impact of synbiotic and probiotic supplementation on antibiotic use duration and postoperative infection risk in patients undergoing gastrointestinal and cancer-related surgery.

Clin Nutr ESPENAug 14, 2026Read summary
Clinical ResearchGastroenterology

Association of computed tomography-derived body composition and complications after radical gastrectomy for gastric cancer: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the association between computed tomography-derived body composition parameters and postoperative complications (POCs) in gastric cancer patients.

Eur J RadiolAug 14, 2026Read summary
Clinical ResearchGeneral Surgery

Decision for preservation or ligation of aberrant left hepatic artery using fluorescence imaging in minimally invasive gastrectomy: a prospective nonrandomized comparative study.

This multicenter, prospective, nonrandomized comparative study evaluated the use of near-infrared fluorescence imaging to guide the preservation or ligation of the aberrant left hepatic artery (ALHA) during minimally…

J Gastrointest SurgAug 14, 2026Read summary

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