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408 articles

June 202613

Clinical ResearchInfectious DiseasesOpen access

Safety and immunogenicity of a booster dose of COVAC-2, a Sepivac SWE™ adjuvanted SARS-CoV-2 recombinant protein vaccine in previously vaccinated healthy adults; a randomized controlled multicentre trial.

This Phase 1 randomized controlled trial assessed the safety and immunogenicity of the COVAC-2 vaccine as a heterologous booster in 60 previously vaccinated adults.

Hum Vaccin ImmunotherJun 10, 2026Read summary
Case ReportObstetrics & Gynecology

Journey from domestic violence to self-reliance: A case report from a tertiary care crisis center.

A 32-year-old married woman with two children experienced prolonged physical, emotional, and economic abuse by her husband, who had alcohol dependence.

Int J Gynaecol ObstetJun 10, 2026Read case
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Excess of post-resistance exercise energy expenditure: a comparison between morning and evening.

This randomized crossover trial examined the impact of morning versus evening resistance exercise on excess post-exercise energy expenditure (EPEEE) in 13 experienced male participants.

Eur J Appl PhysiolJun 6, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

A systematic review on parental vaccine hesitancy for childhood immunizations in the European region: Can findings be generalized?

This systematic review examined parental vaccine hesitancy (VH) for childhood immunizations across Europe, analyzing 49 articles published from 2015 to 2024.

Hum Vaccin ImmunotherJun 5, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Toxic trace elements in fish and seafood from North African coasts: A systematic review and meta-analysis of contamination levels and health risk assessment.

This systematic review and meta-analysis assessed contamination levels of toxic trace elements in fish and seafood from North African coasts.

Regul Toxicol PharmacolJun 5, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Decades of Research in the Chronic Disease Self-Management Program: A Systematic Review and Meta-Analysis of Long-Term Health Outcomes Across Countries.

This systematic review and meta-analysis evaluated the long-term health outcomes of the Chronic Disease Self-Management Program (CDSMP) across various countries, focusing on adults with chronic conditions.

Am J Public HealthJun 4, 2026Read summary
Clinical ResearchPsychiatry

The subjective effects of △9-tetrahydrocannabinol: A systematic review and dose-response meta-regression.

This systematic review and meta-analysis examined the subjective effects of Δ9-tetrahydrocannabinol (THC) in 1020 healthy individuals with infrequent cannabis use.

Neurosci Biobehav RevJun 3, 2026Read summary
Clinical ResearchEndocrinology

Evenly Distributing Daily Dietary Protein Across Three Meals Reduces Women's Snack Food Reinforcement and Intake of Energy-Dense Snack Foods During Weight Loss: A Randomized Controlled Trial.

This randomized controlled trial examined the impact of protein distribution on snack food reinforcement and intake among healthy women aged 20 to 44 with a BMI of 28 to 45.

J Acad Nutr DietJun 3, 2026Read summary
Clinical ResearchInfectious Diseases

Safety and immunogenicity of mRNA-based mpox vaccine candidate BNT166a: an open-label, dose-escalation, first-in-human trial.

This phase 1 open-label trial evaluated the safety and immunogenicity of the mRNA vaccine candidate BNT166a in healthy adults.

Lancet Infect DisJun 3, 2026Read summary
Clinical ResearchGeriatricsOpen access

Effects of exercise on metabolic risk, cardiovascular fitness, and body composition in elderly women of the past decade: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of exercise on metabolic risk, cardiovascular fitness, and body composition in healthy elderly women.

J Int Soc Sports NutrJun 2, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Immune correlates analysis in NextCOVE trial for a next-generation mRNA-1283 COVID-19 vaccine.

The Phase 3 NextCOVE trial evaluated the immune correlates of the mRNA-1283 COVID-19 vaccine in over 10,000 participants aged ≥12 years.

Hum Vaccin ImmunotherJun 1, 2026Read summary
Clinical ResearchInfectious Diseases

A pragmatic randomized trial to evaluate the vaccine effectiveness of bivalent RSV prefusion F vaccine for preventing RSV hospitalizations in adults (DAN-RSV): Trial design update.

The DAN-RSV trial is a pragmatic randomized controlled trial assessing the effectiveness of the bivalent RSV prefusion F vaccine in preventing RSV-related hospitalizations among adults.

Am Heart JJun 1, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Tobacco and cannabis use in the young 'Not in Employment, Education or Training' population: A systematic review and meta-analysis.

This systematic review and meta-analysis examined tobacco and cannabis use among NEET (Not in Employment, Education or Training) youth aged 15-29 years, comparing their usage patterns to those of employed youth and…

AddictionJun 1, 2026Read summary

May 202611

Clinical ResearchPreventive Medicine / Public HealthOpen access

Strategies implemented to increase HPV vaccine uptake and confidence among men who have sex with men and transgender people: A systematic review.

This systematic review evaluated interventions aimed at increasing HPV vaccine uptake and confidence among men who have sex with men (MSM) and transgender individuals.

Hum Vaccin ImmunotherMay 29, 2026Read summary
Clinical ResearchGeriatrics

Wearable devices for improving medication adherence in older adults with chronic conditions: A systematic review.

This systematic review evaluated the impact of wearable devices on medication adherence in adults aged 65 and older with chronic conditions.

Int J Med InformMay 28, 2026Read summary
Clinical ResearchFamily Medicine

Effectiveness of Telemedicine-Based Interventions in Primary Health Care: A Systematic Review in a Universal Health System.

This systematic review evaluated the effectiveness of telemedicine-based interventions in primary health care (PHC) across 22 studies.

Telemed J E HealthMay 27, 2026Read summary
Clinical ResearchInfectious Diseases

Nurse Practitioner-Led, Same-Day, Pre-exposure Prophylaxis Delivery Program for People Who Inject Drugs in the United States: Findings From a Pilot Randomized Controlled Trial.

This pilot randomized controlled trial evaluated a nurse practitioner-led, same-day PrEP delivery model (iRaPID) for HIV prevention among 44 HIV-seronegative people who inject drugs.

J Assoc Nurses AIDS CareMay 27, 2026Read summary
Clinical ResearchPediatricsOpen access

Immunogenicity and safety of an investigational quadrivalent measles, mumps, rubella, and varicella vaccine in children aged 4-6 years: A phase II, randomized, multi-country trial.

This phase II, randomized, multi-country trial evaluated the immunogenicity and safety of an investigational quadrivalent measles, mumps, rubella, and varicella vaccine (MMRVNS) in healthy children aged 4-6 years.

Hum Vaccin ImmunotherMay 26, 2026Read summary
Clinical ResearchNeurology

Association Between Air Pollution Exposure and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated the association between air pollution and the risk of hemorrhagic stroke.

Can J CardiolMay 26, 2026Read summary
Clinical ResearchGeriatricsOpen access

Applying Implementation Science Methods to Prospectively Track the Adaptation of an Evidence-Based Deprescribing Intervention for Use in a New Health System and Country.

This pragmatic clinical trial evaluated the adaptation of the STOP-FALLS deprescribing intervention for older adults within the Kaiser Permanente Washington health system.

Perm JMay 26, 2026Read summary
Clinical ResearchCardiology

Plasma metabolomic signatures of adults at elevated-cardiovascular disease risk show improvements in diet quality in response to medical nutrition therapy.

This randomized controlled trial report evaluated whether plasma metabolomic signatures developed in a controlled feeding study could track diet-quality changes during medical nutrition therapy (MNT).

Nutr Metab Cardiovasc DisMay 26, 2026Read summary
Clinical ResearchGeriatrics

Adherence and effectiveness of multicomponent exercise fall prevention programmes across delivery formats in community-dwelling older adults: a systematic review and multilevel meta-analysis.

This systematic review and multilevel meta-analysis evaluated the effectiveness of multicomponent exercise programmes for fall prevention in community-dwelling adults aged 60 and older.

Arch Gerontol GeriatrMay 20, 2026Read summary
Clinical ResearchInternal Medicine (General)

Interventions that strengthen the patient-clinician relationship improve healthcare outcomes: An updated systematic review and meta-analysis.

This systematic review and meta-analysis evaluated clinician-focused interventions aimed at strengthening patient-clinician relationships across 28 randomized controlled trials involving 18,046 patients.

Patient Educ CounsMay 20, 2026Read summary
Clinical ResearchGeriatrics

Determinants of social participation among community-dwelling older adults: A mixed-methods systematic review.

This mixed-methods systematic review examined determinants of social participation among community-dwelling older adults, analyzing 99 studies.

Int J Nurs StudMay 20, 2026Read summary

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