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1064 articles

September 20267

Clinical ResearchGeriatrics

The effect of vortioxetine on cognitive function in older adults with major depressive disorder: A systematic review.

This systematic review evaluated the effects of vortioxetine on cognitive function and depressive symptoms in older adults (≥65 years) with major depressive disorder.

J Affect DisordSep 1, 2026Read summary
Clinical ResearchNeurology

Plasma Biomarker Effects of Oral Valiltramiprosate/ALZ-801 in Early Alzheimer's Disease from Phase 3 and Phase 2 Trials: Analysis of Core Biomarkers and Correlations with Clinical and Neuroimaging Outcomes.

This study analyzed plasma biomarkers in APOE4 homozygotes with early Alzheimer's disease from Phase 3 and Phase 2 trials of valiltramiprosate/ALZ-801.

DrugsSep 1, 2026Read summary
Clinical ResearchPsychiatry

Clinician perspectives on specialist perinatal mental health service care pathways: An integrative review.

This systematic integrative review examined clinicians' perspectives on specialist perinatal mental health service care pathways.

Women BirthSep 1, 2026Read summary
Clinical ResearchPsychiatry

Comparative efficacy of interventions for transdiagnostic anhedonia: a network meta-analysis.

This network meta-analysis compared interventions for anhedonia across transdiagnostic populations, including people with major depressive disorder or schizophrenia and healthy individuals with trait anhedonia.

Psychiatry ResSep 1, 2026Read summary
Clinical ResearchPsychiatry

Effectiveness of nature therapies for treatment of posttraumatic stress disorder: A systematic review and exploratory meta-analysis.

This systematic review and exploratory meta-analysis assessed nature therapies for adults with posttraumatic stress disorder (PTSD). It included 11 studies with 654 participants; six contributed to the meta-analysis.

Complement Ther MedSep 1, 2026Read summary
Clinical ResearchPsychiatry

Predictors of engagement and response in cognitive behaviour therapy for psychosis: A systematic review.

This systematic review examined predictors of engagement with and response to cognitive behavioural therapy for psychosis (CBTp) across clinical high risk, first-episode psychosis, and schizophrenia populations.

Schizophr ResSep 1, 2026Read summary
Clinical ResearchPsychiatry

The efficacy of physical exercise on body mass index in schizophrenia patients: A systematic review and meta-analysis on exercise prescription, intensity, and delivery.

This systematic review and random-effects meta-analysis assessed randomised controlled trials of physical exercise and BMI in people with schizophrenia, including whether exercise type, delivery, intensity, and duration…

Schizophr ResSep 1, 2026Read summary

August 202617

Clinical ResearchPsychiatry

Pharmacotherapies for Co-Occurring Stimulant Use Disorder and Attention-Deficit/Hyperactivity Disorder: A Network Meta-Analysis.

This network meta-analysis evaluated pharmacotherapies for adults with co-occurring stimulant use disorder (StUD) and attention-deficit/hyperactivity disorder (ADHD).

J Clin PsychiatryAug 31, 2026Read summary
Clinical ResearchPsychiatryOpen access

Nonalcoholic Beverage Consumption and the Risk of Depression, Anxiety, and Stress: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the relationship between nonalcoholic beverage consumption and mental health outcomes, including depression and anxiety, across 59 studies with over 2 million…

Depress AnxietyAug 31, 2026Read summary
Clinical ResearchPsychiatry

Retinal electrophysiology in mood disorders: Toward clinically relevant biomarkers. A systematic review and meta-analysis.

This systematic review and meta-analysis examined retinal electrophysiology, specifically Electroretinography (ERG), in mood disorders such as major depressive disorder (MDD) and bipolar disorder (BD).

J Affect DisordAug 31, 2026Read summary
Clinical ResearchPsychiatryOpen access

Eating Compulsion Behavior Assessment in Patients Before and After Bariatric Surgery: A Systematic Review.

This systematic review examined 22 PubMed/Medline articles on compulsive eating and related psychological factors in patients before and after bariatric surgery.

Obes SurgAug 31, 2026Read summary
Clinical ResearchNeurologyOpen access

APOE in subjective cognitive decline: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prevalence of the APOE ε4 allele in individuals with subjective cognitive decline (SCD).

J NeurolAug 30, 2026Read summary
Clinical ResearchPsychiatry

Antidepressant effects of facial botulinum toxin a injections: Insights from randomized controlled trials.

This systematic review and meta-analysis evaluated the efficacy and safety of facial Botulinum toxin A (BoNT/A) injections in treating depressive disorders, involving 636 participants across eight randomized controlled…

J Affect DisordAug 30, 2026Read summary
Clinical ResearchPediatrics

Behavioral interventions for sleep problems in autistic children: A systematic review.

This systematic review evaluated the effectiveness of behavioral sleep interventions for sleep problems in autistic children under 18 years.

Sleep MedAug 29, 2026Read summary
Clinical ResearchPsychiatry

Clinical speech AI for schizophrenia: Diagnostic accuracy of speech- and language-based digital biomarkers in a PRISMA-DTA systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the diagnostic accuracy of speech- and language-based digital biomarkers for schizophrenia, analyzing 46 reports.

Int J Med InformAug 29, 2026Read summary
Clinical ResearchPsychiatryOpen access

Relationships between empathy, symptoms, and functioning in first episode psychosis.

This study examined associations between empathy, symptoms, and functioning in 100 people with first-episode psychosis (FEP) participating in a larger randomized controlled trial.

Schizophr ResAug 28, 2026Read summary
Clinical ResearchPsychiatry

Baseline inflammatory profile is associated with short-term antipsychotic-induced weight gain in first-episode psychosis: results from the OPTiMiSE study.

This analysis of the OPTiMiSE randomised trial examined whether baseline inflammatory markers were associated with short-term antipsychotic-induced weight gain in 208 people with first-episode psychosis treated with…

Schizophr ResAug 28, 2026Read summary
Clinical ResearchCardiology

Patient-reported outcome measures for depression or anxiety symptoms in patients with cardiovascular disease: A COSMIN systematic review.

This systematic review evaluated the methodological quality and measurement properties of patient-reported outcome measures (PROMs) for depression and anxiety in adults with cardiovascular disease (CVD).

J Psychosom ResAug 27, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Prevention of postpartum methamphetamine use with micronized progesterone trial (PROMPT): A pilot randomized controlled trial.

The PROMPT trial evaluated the feasibility and safety of micronized progesterone in preventing postpartum methamphetamine use among individuals with methamphetamine use disorder.

Drug Alcohol DependAug 27, 2026Read summary
Case ReportOncology (Medical)

Catatonia in a 13-Year-Old With T-Cell Lymphoblastic Lymphoma Following Intrathecal Methotrexate.

A 13-year-old girl with T-cell lymphoblastic lymphoma exhibited agitation, confusion, and catatonia five days after receiving intrathecal methotrexate.

J Pediatr Hematol OncolAug 27, 2026Read case
Clinical ResearchPsychiatry

Prevalence of Mental Disorders in Parents With Intellectual Disabilities: A Systematic Review.

This systematic review examined the prevalence of mental disorders in parents with intellectual disabilities (IDs) during pregnancy, postpartum, and parenthood, involving 42,207 individuals.

J Intellect Disabil ResAug 27, 2026Read summary
Clinical ResearchPsychiatry

Prevalence of depression, anxiety, and post-traumatic stress symptoms among black post-secondary students in North America: A systematic review and meta-analysis.

This systematic review and meta-analysis examined the prevalence of depression, anxiety, and PTSD symptoms among Black post-secondary students in North America.

Compr PsychiatryAug 26, 2026Read summary
Clinical ResearchPsychiatry

Open Dialogue versus treatment as usual for adults presenting in crisis to mental health services in England (the ODDESSI Trial): a multisite cluster-randomised trial.

The ODDESSI Trial, a multicenter cluster-randomised trial, evaluated the effectiveness of Open Dialogue versus treatment as usual for adults in crisis within mental health services in England.

Lancet PsychiatryAug 26, 2026Read summary
Clinical ResearchPsychiatry

Baseline emotional distress predicts psychological response to a social media reduction intervention in distressed youth: a precision mental health approach.

This randomized controlled trial investigated the impact of a social media use reduction intervention on anxiety and depressive symptoms in youth with varying levels of baseline emotional distress.

J Affect DisordAug 26, 2026Read summary

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