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785 articles
August 202614
Modified endoscopic mucosal resection versus endoscopic submucosal dissection for rectal neuroendocrine tumors ≤10 mm: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the efficacy of modified endoscopic mucosal resection (m-EMR) versus endoscopic submucosal dissection (ESD) for rectal neuroendocrine tumors (r-NETs) ≤10 mm, involving…
Randomized Placebo-Controlled Trial of Psyllium Fiber in Functional Abdominal Pain Disorders in Children.
This randomized controlled trial evaluated the efficacy of psyllium fiber in children aged 5-18 with functional abdominal pain disorders (FAPD), including IBS and FAP-NOS.
Hepatic sarcoidosis presenting with portal hypertension without histologically established cirrhosis and reticular hepatic imaging features.
A 50-year-old man was evaluated after non-caseating granulomas were found incidentally on the liver surface during surgery.
Primary Hyperparathyroidism-Induced Acute Pancreatitis: Case Report and Systematic Review.
A 61-year-old man presented with acute pancreatitis and severe hypercalcemia, with total serum calcium of 3.54 μmol/L (14.16 mg/dL) and parathyroid hormone of 640.5 pg/mL.
Efficacy and safety of human albumin combined with furosemide in acute decompensated heart failure with hepatic dysfunction.
This randomized controlled trial evaluated the efficacy and safety of intravenous albumin combined with furosemide in 241 patients with acute decompensated heart failure and hepatic dysfunction.
Clinical Heterogeneity and Long-Term Outcomes of Pediatric Gastrointestinal Stromal Tumors: A Series of Four Patients Highlighting SDH-Deficient and SDH-Intact Subtypes.
This report details four pediatric patients with gastrointestinal stromal tumors (GISTs) over 19 years. Two patients had SDH-deficient tumors, with one experiencing metastatic relapse.
Modulatory role of Blastocystis-derived solubilized antigens in colorectal carcinogenesis: A systematic review.
This systematic review examined the immunomodulatory effects of Blastocystis-derived solubilized antigens (BSA) on colorectal cancer (CRC) using six experimental studies.
Metabolic ketosis attenuates NLRP3 inflammasome activation and is associated with improvements in hepatic steatosis and liver stiffness in MASLD: a pilot randomized controlled trial.
This pilot randomized controlled trial investigated the effects of a C8-enriched medium-chain fatty acid formulation on metabolic and hepatic outcomes in 20 participants with metabolic dysfunction-associated steatotic…
Neoadjuvant Chemoradiotherapy Versus Chemotherapy in Patients with Pancreatic Ductal Adenocarcinoma: A Systematic Review and Meta-analysis of Randomised Controlled Trials.
This systematic review and meta-analysis of randomised controlled trials compared neoadjuvant chemoradiotherapy (NACR) with neoadjuvant chemotherapy (NAC) in patients with pancreatic ductal adenocarcinoma.
S1P receptor modulators for moderate-to-severe ulcerative colitis: a systematic review, meta-analysis, and trial sequential analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of S1P receptor modulators in adults with moderate-to-severe ulcerative colitis, incorporating data from ten RCTs.
Clinical and genetic analysis of Liver-Predominant ornithine transcarbamylase deficiency caused by a novel de novo OTC sequence variant in a female child.
Ornithine transcarbamylase deficiency (OTCD) is the most common urea cycle disorder. Although the classical presentation is dominated by hyperammonemia-related neurological manifestations, some patients may present with…
Micro(nano)plastics as dynamic vectors for hazardous agents: Bridging environmental transport to health impacts.
This systematic review examines the environmental transport and health impacts of micro(nano)plastics (MNPs), highlighting their role as vectors for hazardous agents.
Potentially fatal hemorrhagic duodenal ulcers caused by cytomegalovirus infection complicating autoimmune hepatitis with acute liver failure, successfully treated with multiple interventional radiology procedures.
A patient treated with steroid pulse therapy for acute-onset autoimmune hepatitis progressed to acute liver failure. Liver failure improved after plasma exchange and continuous hemodiafiltration, but multiple duodenal…
Gastrointestinal Adverse Events Following Rotavirus Vaccination in Children: A Systematic Review.
This systematic review assessed gastrointestinal adverse events after RV1 and RV5 rotavirus vaccination in children, drawing on randomised trials, meta-analyses, and case reports published from 2007 onwards.
July 202610
Cost-of-Illness of Irritable Bowel Syndrome: A Systematic Review.
This systematic review analyzed the economic burden of irritable bowel syndrome (IBS) across 33 studies from 14 countries. It found that mean annual direct healthcare costs per patient varied significantly, from US$193…
Conventional Liver Retransplantation with Caval Replacement for Suprahepatic Inferior Vena Cava Stenosis Secondary to a Malpositioned TIPS: A Case Report.
A 64-year-old male with alcoholic cirrhosis and a history of TIPS placement developed refractory ascites and hepatic encephalopathy, leading to liver transplantation.
Tofogliflozin alters amino acid metabolism in gut microbiota linked to hepatic transcriptomic signatures in MASLD.
This prespecified sub-analysis of a randomized controlled trial examined gut microbiota–liver associations in participants with MASLD and type 2 diabetes treated with tofogliflozin or glimepiride.
Role of bioprocessing in modifying cardiometabolic outcomes of an oat-based dairy alternative in a randomised controlled clinical intervention.
This randomized controlled trial investigated the effects of fermented and non-fermented oat-based products on cardiometabolic outcomes in 56 adults with mild metabolic deterioration over 12 weeks.
Efficacy of molecular adsorbent recirculating system albumin dialysis in the treatment of hepatic encephalopathy associated with liver failure: a meta-analysis.
This meta-analysis evaluated the efficacy and safety of the molecular adsorbent recirculating system (MARS) in treating hepatic encephalopathy due to liver failure.
Gastric atrophy and gastric cancer: a meta-analytical assessment of risk and the influence of topographical distribution.
This meta-analysis evaluated the risk of gastric cancer associated with gastric atrophy in 21,006 patients across ten studies.
Disseminated echinococcosis with discordant serology: a rare case of molecularly confirmed Echinococcus granulosus sensu stricto G1 in Poland.
A 24-year-old man from Morocco, living in Poland, presented with abdominal distension, pain, and gastrointestinal obstruction.
Clinical Trial: Phase 3 Trial of Resmetirom Versus Placebo in Metabolic Dysfunction-Associated Steatohepatitis-Reanalysis of Fibrosis Stage 2-3 Subset.
This phase 3 randomized controlled trial analyzed the efficacy of resmetirom in patients with metabolic dysfunction-associated steatohepatitis (MASH) and F2 or F3 fibrosis.
Recombinant Human Thrombopoietin Reduces the Need for Platelet Transfusion in Patients With Chronic Liver Disease and Thrombocytopenia.
This multicenter, randomized, double-blind, placebo-controlled phase III trial evaluated recombinant human thrombopoietin (rhTPO) in 120 adults with chronic liver disease-related thrombocytopenia undergoing elective…
Multisystemic Anesthetic Management and Patient Blood Management in Urgent Liver Transplantation for Acute-on-Chronic Liver Failure: A Case Report.
A 42-year-old woman with chronic cholestatic liver disease developed acute-on-chronic liver failure, necessitating urgent liver transplantation.
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